جستجوی مقالات مرتبط با کلیدواژه « phytochemical compounds » در نشریات گروه « زیست شناسی »

The poisonous substances in plants are mostly alkaloids, glycosides, organic acids, resins, resinoids, and mineral compounds. A poisonous plant is a plant that can be harmful or fatal to humans or other animals if touched or eaten in sufficient quantity. If used in small amounts and in the right proportion, these plants can be used as herbal medicines with medicinal properties. The beauty of these plants hides their toxicity. Scientific understanding of plant toxins and their effects has greatly increased. Poisonous plants that cause serious problems or even death are considered as "plant biological weapons". Knowledge about poisonous plants is still insufficient and it is very important to identify some species that cause poisoning and death in humans. The purpose of this article is to provide information about poisonous plants, existing toxic compounds and symptoms when consumed, as well as their medicinal uses.

Microalgae-based products are an emerging class in food and nutrients. Due to population growth and modernization of lifestyle, consumption of high-calorie foods has become common, which causes the problems such as obesity, heart disease and diabetes, which require the use of healthy foods containing vitamins, minerals, PUFA. For this reason, there has recently been a great deal of interest in separating new compounds from marine resources because of their health benefits. Among marine resources, algae are valuable resources with diverse structures of bioactive substances. Algae are important sources of phytochemicals with antioxidant properties that are directly and indirectly involved in the food industry. Many compounds such as carotenoids, phycobilin, unsaturated fatty acids, polysaccharides, vitamins and biologically active molecules that are important for use in human health have been identified in algae. Long-chain unsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid are very important for the body's metabolism in humans. Chorophylll and bryophyte algae are used to extract these essential fatty acids. Macro and microalgae have a wide range of genetic and biodiversity sources that increase their importance due to their high nutritional value, trace minerals, high protein content and unsaturated fatty acids have been used in human, animal and aquatic nutrition. Therefore, in the present study, the properties, that potential and application of algae for the preparation of beneficial foods are discussed.

In order to evaluate genetic diversity using phenotype and phytochemical properties of sweet violet (Viola odorata), 10 regions of Mazandaran and Golestan provinces were studied. Phytochemical traits such as phenol content, flavonoid, antioxidant capacity, chlorophyll a, chlorophyll b, total chlorophyll, and morphological characters of leaf size, petiole length, pedicel length, and root length were evaluated. Sari and Kosout genotypes had the highest chlorophyll b and total chlorophyll contents and the Sari ecotype had the highest flavonoid content. The highest level of antioxidant capacity was observed in Sari and Vari ecotypes. The ecotypes of Zanglab, Aq Cheshmeh, Tangeh Chehel Chai with lower height showed the highest total phenol contents. Results of morphological evaluation showed that ecotypes of Vari, Sar,i and kosout had the longest leaves and  ecotypes of Azni and Vari had the longest roots. Also, ecotypes of Vari, kosout, Tangeh Chehel Chai, and Zanglab had the highest petiole length and Tangeh Chehel Chai ecotype had the highest leaf number. Correlation of traits showed that leaf height, leaf width, petiole length, leaf number, leaf flavonoid, and leaf phenol contents of sweet violet decreased with increasing altitude. In general, Sari, Vari, and Kosoot ecotypes from Mazandaran province had superior genotypes for most of the traits that could be used for future breeding programs.

The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is one of the common factors of mortality worldwide in the 21st century. A lot of research is being done in the world with the aim of introducing new and effective SARS-COV-2 antiviral compounds, especially herbal compounds. The purpose of this study to screening main protease (Mpro) inhibitors and spike glycoprotein from among plant phenolic and terpenoid compounds using bioinformatics tools.Three dimension and chemical structures of virus proteins and plant phenolic and terpenoid compounds were retrieval from Protein Data Bank and Pubchem database respectively. Finally, plant compounds on the main protease (Mpro) and virus S virus, molecular docking was investigated using iGemdock 2.1 software and then,In the next step, physicochemical properties of the candidate plant compounds for permeability, solubility and gastrointestinal absorption were predicted using SwissADME software.4 terpenoid compounds, glycyrrhizic acid, Saikosaponin B2, Polyphyllin I and Withaferin A and 7 phenolic compounds, EGCG ، Rosmarinic acid ، Silibinin ، Chlorogenic acid ، Proanthocyanidin ، Procyanidin B2 , Anthocyanin with Strong binding energy compared to reference medicinal compounds such as Azithramycine and Remdesivir are good candidate for inhibiting spike Glycoprotein and the main protease of the virus (Mpro).According to results both phenolic and terpenoid compounds compared to standard chemical drugs had good inhibitory effects for Mpro proteinase and Spike glycoprotein virus and can be good candidates for in vitro and in vivo studies.