جستجوی مقالات مرتبط با کلیدواژه « Boldenone » در نشریات گروه « زیست شناسی »

In addition to their therapeutic purposes, steroids have been abused a lot and have had many side effects. Therefore, this study aims at investigating the effect of eight weeks of aerobic exercise on structural and biochemical changes in the heart tissue of male Wistar rats receiving therapeutic dosages and abuse of Boldenone steroid. Therefore, 49 male rats with 12 weeks of age and 190 g mean weight were divided into 7 groups: control group, sham, therapeutic dosage (2 mg / kg), abuse dosage (5 mg / kg), aerobic exercise, aerobic exercise + therapeutic dosage and aerobic exercise + abuse dosage. Injections were given in the same day of the week on the back of rats with a graduated insulin syringe and placebo was used. The aerobic protocol included running five days a week for eight weeks on a rodent treadmill at a speed of 30 meters per minute and 60 minutes training. The samples were first anesthetized and blood and tissue samples were transferred to the relevant laboratories. The results were also analyzed by SPSS software and one-way analysis of variance and Bonferroni post hoc test with a significance level of 0.05. The results showed that there was no significant difference between the groups in final weight gain and cardiac troponin (p <0.05). Also, plasma testosterone levels in steroid-receiving rats decreased significantly in both therapeutic and abusive dosages compared to the exercise groups (p <0.05). On the other hand, the amount of running distance in rodent aerobic function test in steroid and exercise groups was significantly higher than other groups (p <0.05). Generally, data showed that aerobic exercise can prevent the reduction of endogenous testosterone but it has no effect on cardiac troponin levels and rat weight. In addition, Boldenone steroid appears to be effective on increasing the aerobic function of rats.

Anabolic-androgenic steroids popular among athletes have many beneficial and harmful effects on the body. Therefore, the aim of this study was to explain the effect of 8 hours of moderate intensity resistance training with licorice and Boldenone extract on sperm cells, Sertoli and Leydig testicular tissue of male rats.

For the present experimental study, 40 8-week-old male rats weighing 20-220 g were selected and divided into 8 groups of 5, including healthy control, resistance training, and bulldon, Licorice, Boldenone + Licorice, Boldenone, Resistance Training, resistance training + licorice and resistance training + Boldenone + licorice were divided. Then, the resistance training groups performed moderate-intensity training 8 times a week and three times a week, the Boldenone groups received 5 (mg / kg) Boldenone once a week, and the licorice groups received weekly exercise. They received 500 (mg / kg) licorice three times. 48 hours after the last training session, rats were anesthetized by injection of ketamine (70 mg / kg) and xylarine (10 mg / kg) and after incision in the anterior part of the abdominal wall, testicular tissue was removed and tested Stored in refrigerator-80. Finally Data were analyzed using three-way ANOVA and Tukey post hoc tests.

The results showed that there was a significant difference between the means of spermatoid, sertoli and testicular tissue of male rats in different groups.

According to the results of the present study and the effect of exercise and licorice, it is recommended that athletes use these exercises and licorice in consultation with a physician.