جستجوی مقالات مرتبط با کلیدواژه « Omega-6 » در نشریات گروه « زیست شناسی »

This study was designed to evaluate the levels of some biomarkers, including Galectin-3, Periostin, and Interleukin-33 in male albino rats induced as asthma disease model using albumin extracted from the egg. In addition, the histological and physiological indices were investigated to reveal of the protective role of fish oil (omega -3) (2-4mg/kg of body weight) against asthma induced by albumin for four weeks. These biomarkers are new diagnostic biomarkers for asthma-induced disease by albumen extracted from the egg and aluminum hydroxide. For this purpose, forty male albino rats were treated during 2020 to December 2020. The experimental animals are divided into four groups included: (1) treated group: ten animals for one month administrated with 2mg/kg omega-3, (2) 10 animals for one month administrated with 4mg/kg omega-3, (3) asthma induced group with 10 animals, and control group 10 animals. The results showed significant increases in serum concentrations of Galectin-3, Periostin, and Intrleukin-33 in induced asthma albino rats group (P<0.05), while there was a significant decrease in serum concentrations of Galectin-3, Periostin, and Interleukin-33 in the groups which treated with omega-3 fish oil as compared with induced asthma albino rats group (P<0.05). The histological sections of albino rats’ lungs revealed asthma induction in lung tissue which represented by degeneration, necrosis and high amount of the mucous production in bronchioles as well as infiltration of inflammatory cells around bronchioles while effects of albumin in bronchi and trachea sections showed sloughing, degeneration and necrosis around the epithelium of bronchioles. Based on the results, fish oil omega-3 has improved most histological and physiological deterioration.

Fatty acid composition of fish is one of the key factors for the evaluation of fish nutritional value and it could be different based on fish species, habitat, nutrition and etc. The aim of the present study was to evaluate the fatty acid composition of five commercially important freshwater fish from the fish market. Studied fish were as follows: Barbell, Luciobarbus pectoralis (Heckel, 1843), Chub, Squalius cephalus (Linnaeus, 1758), Common carp, Cyprinus carpio (Linnaeus, 1758), Brond-snout, Chondrostoma regium (Heckel, 1843) and Longspine scraper, Capoeta trutta (Heckel, 1843). The determination of fatty acid contents of the fish fillets has been conducted through Gas-chromatography. Results of the present study showed that Fillets of Luciobarbus pectoralis with 43.49% had the the highest amount of fatty acids and Cyprinus carpio had the highest amount of saturated fat (SAF) of 29.43%, the fillets of Luciobarbus pectoralis had the highest MUFA (Monounsaturated fatty acid) with 18.51%, fillets of Squalius cephalus with 1.87% had the highest amount of PUFA (polyunsaturated fatty acid), fillets of Chondrostoma regium with 1.1% had the highest omega 6, and the fillets of Squalius cephalus had the highest omega 3 (1.87%). The results of the present study revealed that freshwater fish are good sources of n-3 fatty acids, especially EPA and DHA, and could be considered as a valuable source of nutritional ingredients.

Fatty acids (FA) are important nutritional substances and metabolites in living organism. Degenerative diseases related to inappropriate FA consumption form a potential death cause for two thirds of the population living in affluent, industrialized nations. Marine algae represent a considerable part of the littoral biomass. Many algal species have long been used as human food, animal fodder and source of valuable substances. In addition, algal components are of interest from a pharmaceutical point of view. Marine algae are rich in fatty acids (FAs) especially polyunsaturated fatty acids (PUFAs) and are of potential value as sources of essential fatty acids (n-3 and n-6 series),which are important in the nutrition of humans and animals. Also the n-6/n-3 ratio of macroalgae, because of their high n-3 content, is lower than 10 which is congruent with WHO recommended. Although each phylum of marine macrophytic algae has its characteristic FA pattern but up to now, only a limited number of algal species have been investigated for their FAs composition. Hence, the objective of this review is to explain briefly synthesis and structure of FAs and also to assess the potential of several Chlorophyta, Phaeophyta and Rhodophyta macroalgae as a source of FAs especially PUFAs and very long chain PUFAs (VLCPUFAs).