جستجوی مقالات مرتبط با کلیدواژه « tris(hydroxymethyl)aminomethan » در نشریات گروه « شیمی »

In this research, first, functionalized Fe oxide magnetic nanoparticles based on sulfonated tris(hydroxymethyl)aminomethane/copper (II) nitrate were synthesized as a new, effective and recyclable magnetic catalyst, and then, was used in the reaction of preparing of Various 2-pyrazolines. Finally, the  prepared 2-pyrazolines were  oxidized to  the corresponding 2-pyrazoles under in situ and one-pot conditions, in such a way that, under optimal conditions, a wide and different range of unsaturated α, β-unsaturated  ketones (trans-chalcones) that had various functional groups including electron-donating and electron-withdrawing groups, were successfully transformed into the corresponding final products under easy and mild conditions. All products were obtained in good to excellent yields and no by-product was observed. The new synthesized magnetic nanocatalyst was characterized by various methods including infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray (EDAX), X-ray diffraction (XRD), elemental analysis (CHN) and analysis Thermogravimetry (TGA). The catalyst was easily recycled by the external magnetic field and was used for several times without observing a significant and effective decrease in its catalytic activity. Also, the structure of various synthesized 2-pyrazoles were confirmed by comparing their physical characteristics including melting point with the reported samples and also by infrared spectroscopy (FT-IR), proton nuclear magnetic resonance spectrum (1H-NMR), carbon nuclear magnetic resonance spectrum (13C-NMR) and elemental analysis. Finally, no using of harsh reaction conditions, the no by-product formation, as well as the ability to recycle and reuse the catalyst, made this method an environmentally friendly method.

In this work, new nanomagnetic particles/Tris (hydroxymethyl)aminomethan functionalized with melamine/Cu(II)nitrate were synthesized and characterized. Next, the catalytic activity of these new magnetic nanoparticles was evaluated in the reaction between sodium azide and different benzontriles in the synthesis of various tetrazoles which possess importance in pharmaceuticals and agriculture. As this catalyst has shown a good catalytic activity, this procedure has led to the synthesis of these products in short reaction times and high yields. Characterization of the magnetic catalyst was carried out by different techniques namely IR, SEM, XRD, VSM, CHN and TGA. Moreover, tetrazole derivatives were characterized using IR, 1HNMR and 13CNMR spectroscopy analysis and also their melting points compared with the reported documents. This catalyst was reused for several runs without any specific loss in its catalytic activity. Finally, mild reaction conditions, no by-products and also recoverability and reusability of the catalyst made this method an environmentally friendly approach.