جستجوی مقالات مرتبط با کلیدواژه « nanocomposite » در نشریات گروه « شیمی »

The objective of this research was to explore targeted drug delivery of ibuprofen, a nonsteroidal anti-inflammatory drug, in order to minimize its side effects for patients requiring long-term and continuous use. To achieve this, a ZnO/NiO nanocomposite was synthesized as a carrier for the drug using a simple co-precipitation method. The structural and morphological properties of the nanocomposite were analyzed using XRD, SEM, and EDS techniques, revealing an average diameter of approximately 65 nm. Subsequently, ibuprofen was successfully loaded onto the nanocomposite with the assistance of mint extract as a covering agent. The presence of ibuprofen in the prepared drug-composite sample was confirmed by FT-IR analysis. In vitro investigations were conducted to determine the release of the loaded drug from the brush nanocomposite, which was found to be 20.4%. This research introduces a new green nanostructure in the drug delivery process.

In this work, new nanocomposite coatings based on epoxy with different percentages (wt.%) of organic clay containing iron oxide and zinc oxide nanoparticles as additives have been prepared. In this context, iron oxide (Fe3O4) and zinc oxide were primarily prepared by a chemical coprecipitation method. Next, intercalated montmorillonite K10 (Mont K10) was synthesized by stabilization of surface-active ingredients such as cetyltrimethylammonium bromide (CTAB) and diethylenetriamine penta methylene phosphonic acid (DTPMP). The prepared Fe3O4 or ZnO were then located within the interlayers and on the external surface of the organoclay to fabricate the novel additives. These additives were dispersed in the epoxy resin and used as nanocomposite coating on the substrate. The structure and morphology of coatings were characterized using XRD, FT-IR and SEM. The effect of adding nanoparticles on the corrosion resistance behavior and mechanical properties of the coatings were investigated by Electrochemical Impedance Spectroscopy (EIS), Salt Spray, pull off and Hardness test. The results of EIS and Salt Spray tests showed that the corrosion resistance of the coating significantly improved by incorporation of CTAB-modified clay in the epoxy matrix. Furthermore, according to the results of pull off and Shore D tests, the mechanical properties such as interfacial adhesion and hardness of coating containing CTAB-clay showed the best performance. In addition, SEM images showed that embedded nanostructures in epoxy coating resulted in a denser, more uniform and less porous layer in comparison with pure epoxy which can effectively prevent the corrosion of the underlying metal by creating high blocking properties.

Radiation shielding materials and components of shielding structures should have good mechanical properties, long-term usability and appropriate flexibility. Nano composites have good micro structural and mechanical properties in different conditions. This article examines the principles of gamma ray shielding, including the interaction of gamma rays with matter, bismuth-based hetero junction nano composites by combining specific concentrations (90, 90, 85, 80 percent) of bismuth oxide with vanadium as a protective material for effective radiation protection. Gamma pays. Discusses various methods of evaluating gamma ray shielding, including measurement techniques and computer simulations using the Geant4 Monte Carlo tool. Also, to check the performance of these nano composites, we have calculated effective parameters in gamma ray attenuation, such as mass attenuation coefficient, mean free distance, one-tenth layer and accumulation coefficient. Finally, this article provides an overview of gamma ray shielding, which is used to ensure the safety of people and equipment against radiation.

In this research, a simple and selective electrochemical sensor with high-sensitivity was proposed to detect dopamine. For this purpose, a nanocomposite consist of nickel-multiwalled carbon nanotubes and titanium dioxide nanoparticles was used to modify the carbon paste electrode. The surface morphology of the modified sensor was evaluated by field emission scanning electron microscopy (FESEM) and Fourier transform infrared spectrometry (FTIR). Cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) techniques were used to analyze of the proposed modified electrode electrochemical behavior and to characterize dopamine. The modified electrode used in this study showed an excellent electro-oxidation response to the presence of dopamine. In addition, to optimize the electrochemical sensor response, any change in the voltammetric behavior of dopamine under different pH and scan rates conditions were investigated and phosphate buffer solution was used for this purpose. Under optimal conditions, the dopamine electrocatalytic peak currents are linearly dependent on the dopamine concentration in the range of 0.3-100 µM and the detection limit of 11.68 nM was calculated for it. Also, electrochemical parameters such as the transferred electrons number and the electron transfer coefficient were estimated. The present study findings showed that the sensor has high sensitivity, low detection limit, fast response, long-term stability, significant repeatability and reproducibility, high selectivity and recovery, as well as excellent performance in analyt detection in the real samples, which proves that the proposed electrode can be used in food, medical and environmental applications. The proposed method is simple, fast and inexpensive and can be used as a valuable analytical tool in quality control of the pharmaceutical industry.

In this paper, Mn2+-doped iron oxide nanoparticles/reduced graphene oxide (Mn-IONs@RGO) nanocomposite are fabricated through an electrochemical synthesis procedure for the first time. The electrosynthesis procedure is based on the electrochemical growth of IONs onto the RGO plates electrophoretically deposited on the cathode electrode. X-ray diffraction pattern of the prepared nanocomposite revealed its magnetite crystal structure. For the prepared Mn-IONs@RGO nanocomposite, particle morphology of IONs, Mn2+ cations doping in their crystal structure and presence of reduced GO plates were confirmed through FE-SEM observations, EDS as well as FT-IR analyses. Mn-IONs showed spherical particles with 20-25 nm in size and elemental composition of 71.36 wt% iron, 7.71 wt% manganese and 20.93 wt% oxygen. It was also found that 59.15 wt% iron, 8.42 wt% manganese, 23.67 wt% oxygen and 8.76 wt% carbon are presents within the composition of the synthesized Mn-IONs@RGO sample. The presence of Mn and C in the composition Mn-IONs@RGO revealed doping of IONs with Mn2+ cations and formation of Mn-IONs particles onto RGO layers through electrochemical deposition route. The superparamagnetic nature of the fabricated nanocomposite was confirmed through M-H curve and magnetic data obtained by vibrating sample magnetometer (VSM) analysis. The Mn-IONs@RGO nanocomposite showed magnetic properties of Ms=31.86 emu g–1, Mr=0.07 emu g–1 and Hci=2.29 G.