جستجوی مقالات مرتبط با کلیدواژه "acoustic wave" در نشریات گروه "مکانیک"

These days, investigation on using acoustofluidic microchannels in separation of microparticles and cells is under consideration. Working under optimum efficiency, these microchannels should be designed and manufactured truly. In this work, a new methodology for designing and manufacturing of acoustofluidic microchannels are explained. Then, a metallic microchannel with 2-nodes of pressure wave based on this method was developed. For mass production purpose, a low cost and reliable method which is CNC micromachining is used. Also, to conduct the heat generated by the wave, this microchannel was made out of aluminum and then polishing technique is applied. Then, the performance of this microchannel in agglomerating of human blood cells and BT-20 breast cancer cells to nodal lines was experimentally studied. The results showed that the applied design and manufacturing technique are suitable. Although some tests were performed to find temperature rise of microchannel due to damping effect, it was found that true design method and also using metals with high thermal conductivity can prevent the temperature increase to the point beyond which living cells will be hurt.

Particulate separation has many applications in medicine, biology and industry. In this research, the separation of polystyrene particles with a diameter of 10, 20 and 30 μm in the fluid flow of a microchannel is investigated. The microchannel consists of a spiral region and a straight region under the influence of acoustic waves. In the spiral region, the particles under hydrodynamic effects undergo the initial separation; then the particles enter the straight region of the microchannel, and the final separation of the particles is done by the force generated and exerted through the acoustic waves. The effects of acoustic frequency and the number of spiral region loops on separation are investigated. The results show that for measured dimensions and parameters, at 1 MHz acoustic wave, when the number of loops is 2 for the spiral region, the particles at the end of the path are in a suitable position for separation. In addition, the results show that the separation of particles with this hybrid system is better than that done by the simple methods, and the separation rate can be as high as 100%