جستجوی مقالات مرتبط با کلیدواژه "propofol" در نشریات گروه "شیلات"

Due to the importance of appropriate sedation and immobility of the patient in cataract surgery, this study was performed to compare the safety and efficacy of a combination of ketamine and propofol (ketofol) in two different ratios.

This double-blind, randomized clinical trial was carried out on patients who underwent cataract surgery in Feyz Hospital, Isfahan, Iran. Patients were randomly divided into group I (n=30, ketamine/propofol 2:1 ratio) and group II (n=30, ketamine/propofol 4:1 ratio). The quality of sedation (using Ramsay sedation scale [RSS]), cardiovascular parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), arterial blood pressure, SPO2, and heart rate, as well as patient and surgeon satisfaction, were evaluated in both groups.

The SPO2 and heart rate were significantly lower and higher in group I than in group II during various surgery times, respectively (P=<0.0001 for both comparisons). In terms of patient and surgeon satisfaction, it was found that no patient was dissatisfied with the sedation status in group II, while four patients (13.3%) in group I were dissatisfied (P=0.005). However, RSS, SBP, and DBP were significantly different between the two groups (P>0.05 for all comparisons).

It seems that the use of lower ketamine doses in combination with propofol (4:1) is a safe and preferable option to provide sedation in cataract surgery.

Anesthetic agents are used in fish to decrease stress and mortality during sorting, surgery, diagnosis and artificial fertilization procedure. This study was done to evaluate and compare the efficacy of propofol and clove oil for anesthetizing Capoeta damascina. For this purpose, 40 fish were caught from Arvand River and divided into two groups. After a pilot study, propofol and clove oil were examined in 12.5 mg L-1 and 125 mg L-1 concentrations, respectively. The onset of anesthesia, duration period of anesthesia and recovery time were recorded separately for each group and compared. Results showed that the anesthesia onset of specimens in propofol treatment, was significantly shorter than that of clove oil treatment (p<0.05). Also, recovery time in propofol treatment was longer (p<0.05) than that of clove oil. Based on the results, it was recommended to use propofol instead of clove oil in performing anesthesia for this species due to rapid induction, longer duration and more prolonged effect in immersion method.