جستجوی مقالات مرتبط با کلیدواژه « تمرین اینتروال » در نشریات گروه « پزشکی »

Obesity is a multifactorial phenomenon that can endanger people's health by causing metabolic disorders. The aim of the present study was to compare the effect of high and moderate intensity interval training on the serum levels of irisin and brain-derived neurotrophic factor (BDNF) in obese male students.

In this quasi-experimental study, 30 obese male students with an age range of 28 to 38 years and a BMI > 30 were randomly assigned into three groups of 10; including high intensity interval training, moderate intensity interval training and control. The training program was implemented for 8 weeks and 3 sessions per week. Irisin and BDNF indices were measured after 12 hours of fasting, 24 hours before and after the research.

Irisin levels were significantly increased in the high intensity interval training group (P<0.0001, Es=0.34) and the moderate intensity interval training group (P<0.0001, Es=0.37). No significant difference was observed in the comparison between groups. Also, the levels of BDNF in the high intensity interval training group (P<0.0001, Es=0.53) and the moderate intensity interval training group (P<0.0001, Es=0.36) were significantly increased. No significant difference was observed in comparison between groups.

It is possible that interval training with both high and moderate intensity can improve the health status of obese people by having a favorable effect on irisin and BDNF indicators.

Diabetic neuropathy (DN) leads to the initiation of several pathways, including oxidative stress and destruction of small vessels, as well as the destruction of factors involved in the SR network of muscle. The purpose of this research was to investigate the effect of the high intensity interval training on the expression of genes involved in calcium flow in the EDL muscle of diabetic rats.

The current research was experimental development study. In total, 48 male rats were randomly divided into 4 groups: training diabetes, diabetes, training and control group. The training group performed the interval training program for 4 weeks and 5 sessions per week. Each training session on the treadmill lasted for 44 minutes. The statistical test of two-way variance (two-way ANOVA) was used for analyzing the data.

High intensity interval training led to a non-significant decrease in Stim1 gene expression. And there was a significant decrease in the expression of Orai and MG29 genes in the long extensor digitorum muscle of male rats.

It is possible HIIT training is able to modulate the expression disorder of Orai, MG29, and Stim1 in diabetes, which may be due to various mechanisms such as controlling oxidative stress factors and growth factors. It seems it exerts its beneficial effects on the Side-effects of diabetes.

Formation of free radicals in the kidney cells of diabetics leads to apoptosis of them and eventually nephropathy. The aim of this study was to investigate the effects of intervals and aerobic exercise along with astaxanthin supplementation on the expression levels of BAD, BAX and Bcl2 genes in the kidney tissue of rats with type 2 diabetes.

35 male Wistar rats with an average weight of 197.46±15.55 grams were randomly divided into two non-diabetic (5 healthy controls) and diabetic (30) groups, and after induction of diabetes, they were randomly divided again in 6 groups (with 5 rats in each group) including diabetic control, diabetes+supplement, diabetes+interval, diabetes+supplement+interval, diabetes+aerobic, diabetes+aerobic+supplement. The exercise intervention groups performed the program of aerobic and interval exercises for eight weeks as five days per week. Supplement groups received 3 mg of astaxanthin supplement per kilogram of body weight dissolved in 0.3 ml of olive oil by gavage every day. The expression levels of BAD, BAX, and Bcl2 genes were measured in the kidney tissue of rats with type 2 diabetes. One-way analysis of variance and Tukey's post hoc test were used for data analysis.

All exercise intervention protocols and astaxanthin supplementation had significant effects on the BAD index in the kidney tissue of the type 2 diabetic rats (p=0.001). All groups, except endurance training (p=0.890), had significant effects on BAX index in the kidney tissue of type 2 diabetic rats (p=0.001). Also, the use of astaxanthin supplement along with endurance training caused significant changes in Bcl2 index compared to single endurance training (p=0.001).

The intervention of aerobic and interval exercises with or without astaxanthin supplementation in the eight-week intervention period has positive effects on the apoptotic biomarkers in the kidney tissue of rats with type 2 diabetes.

Non‐alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease. The aim of the present study was to examine the effect high intensity interval training (HIIT) with resveratrol supplementation on Cardiomyocytes expression of MFn1, MFn2 and OPA1 in NAFLD rats.

In this experimental study, forty-eight Wistar male rats were classified into two groups NAFLD (CN, n=40) and control-normal (n=8). NAFLD was induced in rats with high fat diet and then subdivided into five subgroups NAFLD, SHAM, TRNAF, SUPNAF and TRSUPNAF. Training groups have performed a running program on a motor-driven treadmill for eight weeks. Resveratrol (20 mg/kg) was injected into the SUPNAF and TRSUPNAF groups. Forty-eight hours after the last training session, rats were anesthetized; then hearts were excised and immediately frozen in liquid nitrogen and stored at -80°C for measuring the indexes. Statistical analysis was performed using a one-way analysis of variance, and significance was accepted at p ≤ 0.05.

Induction of fatty liver reduced expression of MFn1 (p=0.009), MFn2 (p=0.003) and OPA1 (p=0.002). Also, in TRNAF, SUPNAF and RSUPNAF groups, MFn1 (p=0.010, p=0.048 and p=0.004 respectively), MFn2 (p=0.028, p=0.007 and p=0.011 respectively) and OPA1 (p=0.019, p=0.003 and p=0.006 respectively) increased significantly compared to the NAFLD group.

It seems that exercise training and resveratrol protects cardiomyocytes mitochondria against fatty liver disease, by reactivation fusion.

 Heavy exercise can damage the immune system by oxidative stress. The role of herbal supplements during and after strenuous exercise is unknown. Therefore, the present study aimed to determine hydroethanolic extract of pomegranate peels and a period of high-intensity interval training on the C-reactive protein and antioxidant enzyme activity in rats.

This research was an experimental study. The statistical population was rats, of which 36 Wistar rats were randomly selected and were divided into 4 groups (control, hydroethanolic extract of pomegranate peels, high-intensity interval training, and hydroethanolic extract of pomegranate peels + high-intensity interval training). After 8 weeks of interval training and supplementation, blood samples were taken from the rats. Then, the C-reactive protein and the activity of the antioxidant enzymes of superoxide dismutase and catalase were assessed by 1-way analysis of variance. 

 The results showed that in the group of hydroethanolic extract of pomegranate peels + high-intensity interval training, the superoxide dismutase (P=0.000) and catalase (P=0.003) significantly increased, and the C-reactive protein (P=0.002) decreased. Tukey’s test confirmed the significance of these changes in the hydroethanolic extract of pomegranate peels+high-intensity interval training compared to the control group.

 The combination of high-intensity interval training and hydroethanolic extract of pomegranate peels could strengthen the immune system, potentially enhances athletic performance, and accelerates recovery after exercises. The hydroethanolic extract of pomegranate peels and high-interval training synergistically boost the immune system and increase physical endurance.

IGF-1 is an anabolic hormone that is effective in cell metabolism and growth. Flaxseeds contain unsaturated fatty acids and are useful. Previous studies have shown that physical activity and natural substances affect hormonal levels. Thus the present study aimed to investigate the effect of 10 weeks of high intensity interval training (HIIT) with and without flaxseed oil on plasma IGF-1 level in male rats.

20 adult male Wistar rats were present in study. Animals randomly divided into four groups (five in each group) including control- saline (CS), training- saline (TS), control- flaxseed oil (CO), and training- flaxseed oil (TO) groups. The training groups performed HIIT (10 weeks, five sessions per week, 90–95% VO2 max) on a rodent treadmill. The supplementation groups also received flaxseed oil supplement (300 mg/kg). The rats were sacrificed five days after the last training session. The plasma was collected, and plasma IGF-1 lever evaluated by ELISA method.

Training increased the level of the plasma IGF-1 than non-training groups (P=0.009). The level of plasma IGF-1 was higher in the flaxseed oil-supplemented groups than the saline-treated groups. (P=0.002). The interaction between training and supplementation also led to an increase in plasma IGF-1 level than training or supplement alone (P=0.001).

HIIT and flaxseed oil consumption can increase the IGF-1 in body.

Over weight is one of the most important public health concerns and the most common fat metabolism disorder in humans the purpose of this study was to compare the effect of eight weeks of interval training and vitamin D intake on DPP4 and RBP4 plasma levels of overweight with mean age of 39.92±4.15 , height 159.25±3.8 cm weight 72.73 kg /m2 in this study , 40 subjects were selected purposely and randomly assigned to four groups of exercise , vitamin D training and consumption complement and control . At first , the height , weight , BMI was measured in the subjects the next day , after 14 hours of fasting The initial blood sample was taken at 5 mm from the subject and the levels of RBP4, DPP4 glucose were measured insulin , resistance was measured and then the interval training program included the neighborhood 30 runs were at maximum speed with one and half minutes of active rest between each time for 8 weeks and three sessions per week the subjects were in vitamin D and interval training with vitamin D intake per week A vitamin D capsule with a dose of 50/000 unite taken with lunch for eight weeks in order to compare the pre-test and post test data in each group , t-test was used and for comparison between groups. AVOVA was used. All true calculations , which were considered less than 5% showed that the eight-week training period of vitamin intake Diet and exercise with vitamin D supplementation on biochemical indices including DPP4 , RBP4 fasting insulin glucose insulin resistance and body composition including weight and BMI of overweight women had a significant effect. Our findings indicated that exercise vitamin D and interval training with vitamin D supplementation reducing the risk factors for overweight diseases such as diabetes such as diabetes and cardiovascular disease is possible by reducing DPP4, and RBP4, fasting glucose and insulin resistance.

The aim of this study was to investigate the interactive effect of interval training and ethanol extract of Adiantum Capillus Veneris on the levels of metallothionein in lung male rats. 25 Male Wister rats three weeks with an average weight of 68 ± 9g after two weeks the familiar with the environment were randomly divided into five groups; 6-week control, 9-week control, 6-week training, 9-week training, interactive training and supplement (6-week interval training + 3 weeks Adiantum Capillus Veneris). Adiantum Capillus Veneris herbal supplement after 6 weeks, the daily dose of 200 mg per kilogram of body weight orally supplemented groups were fed. Increasing interval training for 6 sessions per week, each session 30 minutes at a speed of 15 to 70 meters per minute rehearsing. Finally, lung tissue was extracted for measuring the levels of metallothionein. Analysis of data was performed using one-way ANOVA at P≤0.05. The results showed that the interval training significantly increased the level of metallothionein in the 6-week training group (0.52±0.06) compared to the 6-week control group (0.28±0.04), 9-week control group (0.32±0.05), 9-week training group (0.34±0.04) and the combination of training-supplementation (0.38±0.04). However, the interaction training-supplementation did not have significant effect on the levels of metallothionein in the lungs of male rats (p>0.05). According to the results, six weeks of interval training resulted to significant increase in lung metallothionein levels. Probably the interactive effect of Adiantum Capillus Veneris supplementation and interval training can help reduce pulmonary oxidative stress by modulating lung metallothionein levels.

Nonalcoholic fatty liver disease is the most prevalent liver disease in the world. Life style modification particularly physical activity is the most important treatment strategy. The purpose of the present study was to examine effect of resistance training and high intensity interval training on fatty liver biochemical indices, insulin resistance and liver fat.
Subjects and A total 22 with nonalcoholic fatty liver men enrolled and randomized to resistance training or high intensity interval training. The resistance training group performed six multi joint exercises at 65-70 % 1RM. Interval training group performed 6-12 × 60 s intervals at 80-85 % HRmax, each interval separated with 2 min active rest. Both training groups performed training three times per week. The plasma concentration of liver amino transferase enzymes, lipid profile, insulin resistance index and liver fat measured pre- and 72-h after the last training session. The paired sample T test and independent sample T test used for analysis of changes within group and between group differences, respectively.
The plasma ALT concentration significantly decreased in resistance (P= 0.046) and interval (P= 0.011) training groups. The fasting insulin and insulin resistance index in both groups (P≤ 0.001). The liver fat decreased in both groups. The lipid profile significantly improved in both groups. No significant differences observed between groups in any parameter.
It seems that both resistance and interval training are appropriate training strategy for non-alcoholic fatty liver patent and can improve plasma ALT, lipid profile, insulin resistance and liver fat.

Recent studies on cardiovascular risk factors have been focused on the new markers of inflammatory diseases such as C-reactive protein (CRP). This study aimed to examine the effect of aerobic activities such as running on CRP level in overweight female students. In this study، 26 moderately obese female students (mean body weight 82. 5±5. 6 kg، height 166±6. 4cm، age 21. 2±2. 1 years and BMI ≥ 28. 4 kg/m2) were selected purposefully. Participants were divided into the experimental and control groups. Training program which was performed in two sessions per week for eight consecutive weeks was consisted of incremental aerobic exercise with determined heart rate monitored by a polar watch. Post-test blood sample and anthropometric measures were repeated 48 hours after the last training session similar to the pretest conditions. Results indicated that 8 weeks of high-intensity interval training had a significant effect on decreasing the CRP level in obese girls (P=0. 0001). Moreover، a significant difference was seen between the control and experimental groups in mean CPR values (P=0. 047)، while no significant difference was seen between the pre and post tests in the control group (P=0. 28). Considering the strong association between the inflammatory indices and the prevalence of cardiovascular diseases، every factor that decreases these indices can reduce the cardiovascular complications.

Due to the increase in obesity and sedentary lifestyle in today's world, encouraging the individuals to do appropriate and academic physical activities and studying sports programs with different structures are if great importance. The present paper aims to study the effect of 30 minutes interval short courses of running (4 rounds × 7:30 minutes) with a mean intensity of 60-75% of heart rate reserve (HRR) for 6 weeks on body composition and aerobic capacity (Vo2max) in untrained girl university students. Twenty six untrained girl university students aged 19 to 23 years old with a percentage of body fat (PBF) of more than 30 and a Vo2max of less than 40 ml/kg/min were randomly selected and into divided into two groups including training group (n=16) and the control (n=10). Weight, body mass index (BMI), percentage of body fat (BF%), lean body mass (LBM), and maximal oxygen uptake (VO2max) were measured as indicators of health before and after six weeks of trial. Findings of the present study showed that 6 weeks of interval running improved body composition and aerobic capacity of untrained girls. This means that there was a significant decrease in PBF, weight, and BMI of untrained girls. In addition, maximal oxygen consumption showed a significant increase (p≤0.05), while no significant change was observed in lean body mass. Findings of the present study indicate the importance of combining the short courses of work and rest for 30 min in a day. The present study merely discuss the effective role of interval short course training in stimulating and changing physiological adaptations and consequently improving the performance of cardiovascular system and body composition in untrained girls.