جستجوی مقالات مرتبط با کلیدواژه "دایمی" در نشریات گروه "پزشکی"

The prevalence of congenital hypothyroidism (CH) is high in Isfahan (Iran). Considering the high rate of parental consanguinity and the role of dual oxidase 2 (DUOX2) gene in transient and permanent CH due to thyroid dyshormonogenesis، the aim of this research was to investigate the R434X mutation in DUOX2 gene in patients with transient and permanent CH due to dyshormonogenesis. In this descriptive prospective study، patients diagnosed with transient and permanent CH due to dyshormonogenesis (n = 25 and 33، respectively) during CH screening program were selected. Moreover، 30 children were included as the control group. Venous blood samples were obtained to determine the frequency of R434X mutation in DUOX2 gene using real time polymerase chain reaction based on high-resolution melting analysis by specific primers and sequencing method. We did not find any case of the mentioned R434X mutation in DUOX2 gene. Further studies using other methods and on other gene mutations such as pendrin، sodium iodide symporter (NIS) and thyroglobulin are required for more accurate results.

Tooth sizes have been reported to be different in different races. Comparison of sizes of primary and permanent teeth, relationship between mesiodistal widths of deciduous and permanent teeth and diagnosis of discrepancies are clinically important. Awareness of the mean sizes of teeth helps predict the space necessary for tooth eruption in space analysis. In this analytical cross-sectional study, the subjects were selected from patients referring to various departments of Faculty of Dentistry, Isfahan University of Medical Sciences, in two groups of 3-5 and 13-18 years of age. Study casts were provided for all the subjects and the mesiodistal widths of the teeth on the left side were measured by a precision caliper. Data was analyzed by ANOVA and independent t-test (α = 0.05). The mean mesiodistal widths of primary and permanent teeth in both jaws were measured. Gender dimorphism had no role as a factor determining mesiodistal width of the crown between boys and girls. The central and lateral maxillary incisors, canines and second mandibular molars were significantly larger in boys compared to girls (p value < 0.05) and maxillary first premolars were significantly greater in girls compared to boys (p value < 0.05). Mesiodistal mean sizes of primary teeth were bigger than those of American whites, but smaller than the Japanese. Like many other studies, mesiodistal mean sizes of teeth in boys were greater compared to girls. Different results in different studies might be attributed to the type of the study (cross-sectional vs long-term), indexes used, races, measuring techniques, the methods employed etc.

In Angle classification, the maxillary first molar furnishes more nearly than any other tooth or point in the anatomy an exact scientific basis from which to reason on malocclusion. Angle believed that malocclusions are of the mandibular origin.

the purpose of this study was to evaluate the association between some cephalometric parameters and sagittal position of the maxillary first permanent molar.

This was a descriptive analytical study in which 250 lateral cephalometric samples that were randomly selected before orthodontic treatment were examined. The samples were divided into two groups marked as mixed dentition and permanent dentition. Statistical analyses including the linear correlation coefficients and student t-test were used to compare the upper molar position in two groups.

There was no significant correlation between the age, maxillary length, and ANB in two groups. The position of maxillary first molar in the permanent dentition demonstrated a significant positive relationship with ANS-PNS, Jaraback index, and Ba-PTM whereas a significant negative correlation was found with FMA and Basal angle. Moreover, the maxillary first molar position in the mixed dentition showed a significant positive relationship with Ba-A and Ba-PTM.

Based on results found in the present study, the sagittal position of maxillary molar between mixed and permanent dentition was different. Maxillary first molar position in the permanent dentition showed a significant relationship with facial growth pattern, facial depth, and maxillary length. However, more longitudinal studies to confirm the findings of this study are needed.