جستجوی مقالات مرتبط با کلیدواژه "درد عضلانی" در نشریات گروه "پزشکی"

Vitamin D has been shown to reduce exercise-induced muscle damage and muscle soreness; however, further research is needed to establish definitive conclusions. The aim of this study was to investigate the effect of vitamin D supplementation on muscle soreness and recovery after exercise.

A systematic review and meta-analysis was conducted to evaluate the effects of vitamin D intake on muscle soreness and biochemical markers of muscle damage, including myoglobin (MB), creatine kinase (CK), lactate dehydrogenase (LDH), and inflammatory factors such as TNFα and IL-6. Data were sourced from PubMed, Scopus, and Web of Science databases up to February 2024. Analyses were performed to compare vitamin D with placebo, and weighted mean differences (WMD) were calculated.

A total of 11 studies involving 358 athletes and non-athletes were examined. Changes in muscle soreness immediately after exercise due to vitamin D intake were not statistically significant [P=0.70, WMD=-0.07]. However, vitamin D significantly reduced muscle soreness 24 hours after exercise [P=0.04, WMD=-0.40]. No significant changes were observed in CK [P=0.30, WMD=-3.22 U/L], LDH [P=0.30, WMD=-11.86 U/L], or MB [P=0.50, WMD=10.66 ng/ml] immediately after exercise.

Vitamin D may be effective in reducing muscle soreness 24 hours post-exercise, but it does not appear to significantly affect markers of muscle damage, including CK, MB, and LDH, in the timeframes studied. Further research in this area is recommended.

Several studies have investigated the effect of creatine supplementation on indirect markers of muscular damage and sports performance of athletes. However, pooled data from several studies suggest that the benefits of creatine on recovery of athletes are limited. The aim of this study was to investigate the effect of creatine supplementation on post-exercise recovery and muscle injury factors in healthy subjects.

A systematic search of articles published in English and Persian databases until November 2023 was conducted to investigate the effect of creatine supplementation on muscle injury markers creatine kinase (CK) and lactate dehydrogenase (LDH) and muscle soreness in healthy subjects. Weighted mean difference (WMD) and standardized mean difference (SMD) and 95% confidence interval were calculated using random effect model.

A total of 20 studies including 458 subjects were included in the present meta-analysis. The results showed that creatine did not cause a significant change in muscle soreness in any of 24, 48, 72, and 96 hours after exercise compared to the control group. Also, creatine did not cause a significant change in CK in any time spectrum compared to the control group. In addition, creatine did not cause a significant change in LDH in different time ranges after exercise compared to the control group in athletes and non-athletes.

The results of the present study show that creatine supplementation is not effective in reducing muscle soreness and muscle injury factors after exercise.

 Curcumin, the biologically active ingredient of turmeric (Curcuma longa), affects pain processing at different levels. Local mechanisms of action of curcumin are somewhat known, but the central effects at the spinal and supraspinal levels have been less investigated. In this study, the effect of oral administration of curcumin on the formalin-induced muscle pain was investigated. In addition, naloxone (a non-selective opioid receptor antagonist) and AM251 (a cannabinoid 1 receptor antagonist) were used to clarify the possible central mechanism of action of curcumin. 

 For intracerebroventricular (ICV) injections, one stainless steel guide cannula was implanted into in the left lateral ventricle of the brain in anaesthetized rats. Muscle pain was induced by intramuscular (IM) injection of formalin (2.5%, 50 µl) in the right gastrocnemius muscle, and the number of paw flinches and the time spent licking and biting of the injected paw were recorded at 5-min blocks for 1 h.

 A marked biphasic pain response was observed due to formalin injection. Oral administration of curcumin at doses of 25 and 100 mg/kg significantly (p < 0.01 and p < 0.001, respectively) decreased both phases of muscle pain. Pain intensity was not influenced by alone ICV injection of naloxone and AM251 (p > 0.05), whereas the suppressive effect of 100 mg/kg curcumin was inhibited by ICV administration of 2 µg naloxone and 2 µg AM251 (p < 0.001). All the above-mentioned treatments did not alter locomotor activity.

 These results showed that curcumin produced an antinociceptive effect in muscle pain. Central opioid and cannabinoid receptors might be involved in the antinociception induced by curcumin.

Rheumatoid arthritis is an autoimmune and inflammatory disease that can cause chronic pain. The aim of this study was to investigate the effect of acceptance and commitment therapy on muscle pain in patients with rheumatoid arthritis.

This research was a Quasi-experimental design with experimental and control groups. The study population consisted of 245 patients with rheumatoid arthritis under treatment in the physiotherapy ward of Shaheed Beheshti hospital during 2019 in Hamadan. A sample of 30 subject were selected and randomly assigned in two groups of 15 (experimental and control). The pre-test was then performed on both groups. The intervention was performed on the experimental group in 8 sessions (one hour) and the control group did not receive any intervention. After the intervention, post-test was performed in two groups. The research tools included Von Korff et al (1992) chronic pain rate questionnaire. Analysis of covariance used to analyze the data.

The results of analysis of covariance show that there is a significant difference between the mean score of the subscale of pain intensity in the experimental and control groups (P <0.05, F = 5.84). The effect of acceptance and commitment treatment on the severity of muscle pain in patients was 0.18. The results of analysis of covariance also show that there is a significant difference between the mean score of the subscale of disability caused by pain in patients in the experimental and control groups (P <0.05, F = 6.52). The effect of acceptance and commitment treatment on disability due to muscle pain in patients was 0.20.

The results indicate that acceptance and commitment therapy can be used for reduce the severity of pain and disability caused by pain in patients with muscle pain.

Due to the concerns among trainers about relieving muscle pain as soon as possible, this study aimed to investigate the effect of eccentric retraining on muscle pain and Delay Onset Muscle Soreness (DOMS) markers in sedentary young men.

In this study, sixteen inactive healthy young men voluntarily and after written informed consent. Subjects were randomly divided into control (n=8) and experimental (n=8) groups. Both groups performed seventy eccentric contractions in the flexor elbow muscles with 80% of maximal repetition. Muscular pain perception, serum levels of Creatine Kinase (CK), and Lactate Dehydrogenase (LDH) indices were measured before, one, 26, 48 and 72 hours after eccentric training. Independent t-test and Repeated measure analysis variance in the significant level of P≤0.05 used for data analysis.

The sensation of muscle pain and creatine kinase in both groups increased significantly after exercise (P≤0.05), lactate dehydrogenase level was increased in both groups. Still, this increase was not significant (P>0.05). Also, no significant difference in the CK and LDH and pain perception in the measurement stage between the two groups was observed (P>0.05).

This study results showed that retraining isn’t an essential influential variable on muscle pain and DOMS markers. However, more research needs to be done in this area.

Improving physical performance and delaying fatigue by using nutritional supplements always has been interesting in athletes. The aim of this study was to evaluate the effect of six weeks’ watermelon juice on nitric oxide and exercise performance in elite female taekwondo.

Twenty-five elite female taekwondo players (age 21.84±2.26 yrs; BMI 20.87±1.37 Kg/m2; VO2max 38.86±1.97 ml/min/kg) who had a training experience of more than five years were randomly and voluntary divided into two groups of watermelon juice supplement (n=15) and placebo (n=10). Subjects received 500 ml of watermelon juice or placebo 45 minutes before the taekwondo training sessions for six weeks. Blood samples were taken in the brachial vein in two steps; before and after 6 weeks of supplementation. Data were analyzed using dependent and independent t-test (p≤0.05).

The results of this study showed levels of nitric oxide (P=0.016) and VO2max (P=0/001) significantly greater compared to the placebo group. Also, there was a significant decrease in muscle soreness 24 and 48 hours after exercise in the supplement group compared to the placebo group (p≤0.05).

According to the results, watermelon juice will help faster recovery and reduce muscle soreness after 24 and 48 hours follow exercise.

 Muscular pain is a common complication of physical activity. The purpose of this study was to compare the effect of massage with lavender gel and piroxicam gel on exercise-induced muscle pain in male students of Gonabad University of Medical Sciences.

This semi-experimental study was performed on 75 male students of Gonabad University of Medical Sciences in 2018. The Samples were randomly divided into three groups of 25, including a lavender gel massage group, a piroxicam gel massage group, and a placebo gel massage group. The specimens were randomly divided into three groups of 25, including a lavender gel massage group, a piroxicam gel massage group, and a placebo gel massage group. The training program lasted for 45 minutes, including 10 minutes of warming up and doing stretching exercises, 30 minutes of exercises and the main exercises and 5 minutes for cooling. The research instrument was a checklist for the demographic characteristics of the samples and the Thalog malformation questionnaire. Samples completed the Thalog pain questionnaire after completing the exercise and also after the massage. The Mean±SD were used for descriptive statistics. Normaly distributed data were analyticaly analyzed by paired t-test and ANOVA and non-normaly distributed data were analyticaly analyzed by Wilcoxon and Kruskal-Wallis tests.

 The results showed that muscle pain induced by exercise in all three groups after massage was significantly reduced compared to before massage (P<0.001). The results of Kruskal-Wallis test showed that the difference in muscle pain before and after massage with the three gels used 
(P=0.002) was statistically significant. Massage with lavender gel compared to piroxicam and placebo groups was able to reduce more the muscle pain.

 Massage with lavender gel compared to the piroxicam gel and placebo gel can be a better way to reduce muscle pain after exercise.

Aims and Pain is one of the most common health problems. It inherently has a psychological nature and is a complex psychological experience. This research is to investigate the relationship between selfcompassion with pain intensity, catastrophizing, self-efficacy of pain and affect in women with musculoskeletal pain. The Investigation procedure was according to correlational descriptive ones.For this purpose, among women with musculoskeletal pain in Isfahan who were referred to orthopedic clinics and private clinics in winter 2016, 180 persons were selected in accordance to available sampling method.The participants responded to the research tools including Self-compassion, pain multidimensional, pain catastrophizing, pain self-efficacy, positive and negative affects and demographic questionnaires. The data was analyzed using Pearson correlation coefficient and hierarchical regression analysis. Findings: The results of pearson correlational analysis indicated that there was a significant negative relationship between self-compassion and pain intensity, pain catastrophizing and negative affect in the subjects. Also a positive relationship with pain self-efficacy and positive affect was found as the effect of self compassion. The results of hierarchical regression indicated a 10.5 percent of pain intensity variance after age and painful area control, a 14.4 percent of pain catastrophizing variance after education and marriage control, a 5 percent of pain self-efficacy variance after age control, a 10.3 percent of positive affects and 25.2 percent of negative affects after education control in accordance to self-compassion. The results of this study indicate that self-compassion with the control of demographic variables predicts pain intensity, catastrophizing pain, self-efficacy of pain and positive and negative affects.

Electroconvulsive therapy (ECT) is a controlled electrical stimulus that affects central nervous system and leads to convulsion. Such as every other medical procedure, electroconvulsive therapy has some side effects like headache, myalgia, and nausea and vomiting. Patient undergoing electroconvulsive therapy receives deferent anesthetic drugs and some drugs like Midazolam, Atropine etc. to reduce side effects.
This study included 40 patients who were candidates for receiving electroconvulsive therapy. By using convenience sampling, patients were divided into 2 groups of 20 people. Midazolam were given to one group while the other received placebo. Two patients in midazolam group were removed because of short period of convulsion (lower than 20 seconds). The collected data were analyzed using independent t and chi-square tests.
Findings: 16 men (42.1%) and 22 women (57.9%) were studied. The incidence of headache (P 0.050).
Midazolam can reduce convulsion time but in most cases, convulsions last more than 25 seconds, which is in therapeutic range. So, it cannot affect the therapeutic value of electroconvulsive therapy. Preemptive midazolam reduces Post-electroconvulsive-therapy headache, myalgia, and nausea.

Background and Temporomandibular disorders (TMD) are manifested as a group of signs and symptoms diagnosed by pain, malfunction of temporomandibular joint (TMJ) and masticatory muscles. The need to determine the prevalence and factors associated with their communities is emphasized in studies. The present study investigated the incidence of TMD and its symptoms in individuals attending Sari Dental School Clinic, 2014-2015.
A descriptive-analytical study was conducted in 68 individuals (41 females; 27 males) who were selected by random sampling. Demographic and clinical data were obtained by asking questions and examining the patient. The relation between TMD and other variables were analyzed by Chi-square and exact fisher tests. Data was analyzed in SPSS V.22.
A total of 68 patients was investigated of whom 51 (75%) had TMD. Among these five people had headache (P A high incidence of TDM was detected in the population attending Sari Dental School Clinic. Significant relation was found between symptoms and TMD.

Changing life style and decreasing activity among office employees and people who had regular jobs and had un-appropriated cervical situation cause fatigue in cervical muscles and put them in danger reagent.
KINESIOTAPING is an athletic, medical and rehabilitation method that claims for decrease pain, inflation, muscle spasm and preventing athletic damages during upper stationary activities, therefore, this method also use for pain deduction and preventing cervical accidents.
In this research, we study scientific review of KINESIOTAPE (KT) influence on cervical fatigue as a point for initial muscle damage. For this purpose, we study EMG signals for cervical muscles during specific stationary activity in two particular groups, including the one that actually use KT and the reference group.
Review and compare EMG signal mean frequency as an evaluation index for muscle fatigue and comparing the arrival time to fatigue in both groups are intended. Also for studying the immediate effects of KT in group that did not use them, we apply KT after reaching to fatigue and survey the differences in mean frequency.
With using muscle fatigue measurement the results are evidently shown the useful effect of KT; as in most of KINESIO tape users, muscle fatigue decrease.

Background and­ Pain is a multidimensional phenomenon defined as­ “an unpleasant sensory and emotional experience that is associated with actual or potential tissue ­damage” ­. ­Infants and children are vaccinated before two years on several occasions. Many of these vaccines are injectable، and are painful. The aim of this study was to evaluate whether topical tetracaine can reduce the pain of IM DPT injection compared to placebo in infants of two months of age. In this study، 40 infants aged two months were selected by convenience sampling and randomly placed in two groups of case and control. The Infants of experimental group were injected by using topical tetracaine gel %4­­ and those of the other group by a placebo. The intensity of injection was scored by a pediatric registered nurse، using the FLACC pain scale. Although the mean of pain intensity in case group (8. 3) is lower than that of controls (9. 1) and also the time of pain relief، the use of tetracaine could not be significantly effective in reducing the severity of pain due to intramuscular injection of DPT vaccine. ­ Based on the results، there is no significant difference between case and control groups on using tetracaine، but because of low pain intensity in case group، further researches are needed to be done.

Succinyl colin is a frequently used muscle relaxant in short duration and outpatient anesthesia. Muscular fasciculation and muscle pain (myalgia) are the two mild but frequent side effects of this medication. Respecting great discomfort of myalgia for the patients, the aim of this study was to measure the effect of intravenous lidocain injection on the myalgia and muscle fasciculation generated by succinyl coline. This is a clinical trial study which is performed on 100 patients who were candidates for elective short duration anesthesia requiring tracheal intubation. The patients were randomly divided into two groups of 50 patients. The treatment group received 1.5mg/kg intravenous lidocain and the control group received an equinoxes of distilled water intravenously before succinyl cholin injection. The frequency of myalgia and muscle fasciculation due to succinyl colin injection was compared between the two groups. Results of this study showed that, in the treatment group 24 patients (48%) and in the control group 35 patients (70%) complained from myalgia. The difference was statistically significant (p<0.05). Incidence of fasciculation in lidocain group and control group was 34 (68%) and 50 (100%), respectively. The difference between these proportions was also statistically significant (p<0.05). Intravenous lidocain injection before succinyl colin reduced both fasciculation and muscle pain due to succinyl colin. Therefore, application of lidocain in short term and outpatient anesthesia could be recommended.

Musculoskeletal chest pain is a common referral to emergency departments and general practitioners. The terms of costochondritis and musculoskeletal chestpains are often used synonymously. The basis for such diagnosis is held by exclusion. To evaluate the presence of musculoskeletal apparatus pain in patients with angina pectoris, despite their normal cardiac evaluations. 971 patients referred for angina pectoris or chest pain were prospectively collected.Cardiac evaluations included: as history, physical exams, ECG-Chest X Ray, Echocardiography, perfusion scan and angiography as needed. One hundred patients with musculoskeletal symptoms along with normal cardiac evaluations were investigated. This group were examined by experienced physiatrists, history, physical exam, Cervical x ray, EMG/NCS and laboratory were also done in later group. According to our study 10.3 % of patients with chest pain presentations had musculoskeletal rather than any cardiac problems. From 100 patients with musculoskeletal chest pain, mean age of 43.2, with 71% women.38% of them have left scapular pain and 60 % of them have tender points with high frequency in posterior neck muscle and humeral lat epicondyle. Prevalence of abnormal EMG/NCS was 35%, mostly cervical radiculopathy and abnormal cervical x ray was 26%, mostly DJD of cervical spine. This article reviews the causes of musculoskeletal chest pain and suggests an approach to any chest pain its needs more evaluation and more precise management. The results show an association, but not a causal link between musculoskeletal dysfunction and atypical chest pain. A careful physiatric examination including spinal movements and palpation for tendernes are suggested to be performed.