جستجوی مقالات مرتبط با کلیدواژه « علم ژنتیک » در نشریات گروه « پزشکی »

Bioethics is one of the important topics that are discussed and discussed from different ethical, legal and medical aspects. The purpose of this article is to investigate the legal and ethical elements that influence the formation of bioethics. In other words, the aim of the article is to examine this important issue of what legal and moral elements bioethics is composed of.

The mentioned article is descriptive and analytical and the library method is used. Ethical Considerations: In all stages of writing the present research, the originality of the texts, honesty and trustworthiness have been observed.

The interaction of ethics and law in regularizing modern medical developments has led to the formation of the concept of bioethics. Advances in genetic science and technology, medical advances on the one hand and the need to pay attention to ethical guidelines and legal orders on the other hand, have led to the development of bioethical principles. Bioethics prevents possible abuses and adverse consequences for human integrity, dignity, dignity and rights and its observance can guarantee that the progress of science and technology serves humanity and does not violate human rights, human dignity and basic freedoms.

The result is that genetic science as a science that causes the change and creation of animal and human phenomena and has important effects on the continuation of human life should be in such a way that it includes both moral and religious concerns and provides reasons for protecting the standards of human rights. It should be considered and evaluated in order to improve the positive aspects of this knowledge and improve human life.

Several genes affect the prognosis of traumatic brain injury. Most studies have been conducted on E apolipoprotein (APOE). APOE may have beneficial effects in coma recovery and reducing the risk of seizures after trauma. However, allele E4 of APOE is associated with accumulation of amyloid, which causes amyloid angiopathy and extensive intracranial hematoma. Prognosis of traumatic brain injury depends on underlying factors, such as APOE, amyloid deposition, cytoskeletal rupture, diss cholinergic function, oxidative stress and the ability of the central nervous system to response to the injury. There is a little research on the effects of genes on the brain injury. DRD2 and COMT genes related to dopamine function in cognitive processes in the frontal lobes are involved.Inflammation also plays an important role in the pathophysiology of traumatic brain injury and is controlled by the gene IL. Apoptosis after traumatic brain injury is also regulated by the P53 gene. Converting enzyme gene through self-regulation mechanism of cerebral blood flow affect the prognosis of cerebral trauma. CACNA1A gene with its effect on calcium channels and its effect on prevention of brain edema affects the prognosis of brain trauma. Neprilysin gene causes a protease that plays an important role in the degradation of amyloid β protein and delayed plaque formation.
It seems that genetic factors may play an important role on the prognosis of brain injury. Further studies will be clarified this role in details.