جستجوی مقالات مرتبط با کلیدواژه "مایکوباکتریوم لپره" در نشریات گروه "پزشکی"

Leprosy is an infectious disease which primarily affect skin and peripheral nerves. Mycobacterium leprae and Mycobacterium lepromatosis that are the acid-fast bacillus are known to be cause of leprosy. Genetic factors and immunological function have some roles in susceptibility of developing leprosy. There are some cases of familial leprosy.

 Here in, we report a case of familial leprosy which in one member it was symptomatic and others were asymptomatic with positive skin smear for mycobacterium leprosy bacilli.

We recommend in addition to approach and manage lepromatous patients, their families be also evaluated.

Leprosy is a chronic infectious disease that typically affects the skin and peripheral nerves and can cause irreversible disabilities. The objective of this study was to assess the status of disability caused by leprosy in the Golestan Province in Iran. In this retrospective cross-sectional study, patients affected with leprosy whom were referred to Health Network in Golestan Province from April 1971 to September 2008 were studied. Sampling method was simple census method. Data collected from the medical records of patients were statistically described and analyzed. In this 38-year period, from 100 leprosy patients investigated, 68% were men. Average age was 35.6?16.4 years. The majority of cases were in rural areas (78%) and mostly were labor jobs (39%). Clinical type of the disease was multibacillary (MB) in 64% cases. 62% of patients had MDT treatment. The majority of lesions in patients were macules (15%). Performance problem were positive in 6 percent and was negative or uncertain in others. Disability was more common in male patients, and most disable patients were 35-55 years old.Conlusion: Most leprosy patients in Golestan Province had grade 0 or 1 disability.

Leprosy is an ancient deforming disease caused by Mycobacterium leprae, which is still poorly understood and often feared by the general public and even by some in the health care professions. Fortunately, the outlook for patients has dramatically improved over the last three decades with the introduction of multi-drug treatment and management strategies that have somewhat diminished the stigma of this diagnosis. Here we report a case of leprosy of larynx. Case Report: A 45-year-old Afghan man who had presented with cough,dyspnea and hoarseness since many years ago was referred to our clinic due to worsening complaints. Because of the demonstration of acid fast bacilli in the smear of his sputum,diagnosis of tuberculosis was made and anti-tuberculosis treatment was initiated. However, he developed fever and his symptoms worsened,which led to his admission. On examination, there was a tender erythematous nodule in the right supraclavicular region, loss of eyebrows and eyelashes,and disseminated hyper-and-hypo pigmented cutaneous lesions on the abdomen, thorax and back. Chest x-ray was normal. In order to rule out laryngeal tuberculosis, laryngoscopy was done and granulomatous lesions were seen. Laryngeal and skin biopsy was performed. Both specimens revealed numerous acid fast bacilli, macrophages and foamy cells which were suggestive of lepromatous leprosy. Treatment was started based on multibacillary regime of WHO multidrug therapy. In conclusion, this report highlights the importance of systemic involvement in lepromatous leprosy, especially when the initial presentation is laryngitis or respiratory symptoms. Laryngeal leprosy may be mistaken with tuberculosis or laryngitis due to respiratory problems and the existence of acid fast bacilli in respiratory secretions.