جستجوی مقالات مرتبط با کلیدواژه « متابولیسم لیپیدی » در نشریات گروه « پزشکی »

  High-intensity interval training (HIIT), compared with continuous training, can result in relatively more improvement in max exercise capacity, mitochondrial enzymes, and other cellular factors involved in energy metabolism. So the present study was aimed to examine the effect of six weeks of HIIT on the insulin resistance index, HOMA-beta cell, and atherogenic index among overweight men. The participants included 24 overweight men that classified into interval training and control groups. The participants became familiar with the laboratory environment in several sessions, and blood sampling along with the measurement of height, weight, body composition, and maximal oxygen consumption was performed. Fasting blood samples were collected from the participants’ brachial artery in order to measure their glucose, insulin, total cholesterol, HDL, and LDL before HIIT and 48 hours after training. The results indicated significant changes in insulin, insulin resistance, and beta cell function index, however, glucose, lipid profile, and atherogenic index did not show any significant changes. Although the HIIT exercises are performed during a short period of time, they feature the same beneficial effects as those of aerobic exercises and other forms of training that take relatively longer time. It could, therefore, be said that such exercises could help inactive and overweight people to improve their insulin sensitivity and reduce the risk of diseases related to lipid profile, glucose, insulin, and high fat percentage. Therefore, it is suggested that overweight people, and even healthy people, benefit from this type of training

Obesity as one of the most important health problems in the world, involved in the incidence of many chronic disorders. Obese individuals have lower level of vitamins and minerals such as zinc. Zinc is one of trace elements involved in synthesis, storage, release and action of insulin and in pathway of fat and carbohydrate metabolism. This study conducted to assay the effects of zinc supplementation on the insulin resistance, lipid profiles and blood sugar in obese people. This randomized, double blind, placebo-controlled clinical trial was performed on 60 obese people (BMI >30 kg/m2). Duration of intervention was one month. The eligible participants divided in two equal groups: intervention and placebo, randomly. Intervention group received a 30mg/d zinc pill and placebo group received 30mg/d starch. The concentration of serum insulin, insulin resistance index (HOMA-IR), lipid profiles and fasting blood glucose were determined in onset and at the end of study. Zinc supplementation resulted in a significant reduction in serum insulin concentration, insulin resistance index and serum triglyceride at the end of intervention (p<0.05). However, these results were not significant in placebo group. In contrast, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and fasting blood, sugar (FBS) did not change significantly. Zinc supplement had positive effect on the reduction of insulin concentration and insulin resistance index. More studies with longer period of intervention suggested for disclose more mechanisms in this field.