جستجوی مقالات مرتبط با کلیدواژه "نوروپاتی عصب مدین" در نشریات گروه "پزشکی"

Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression neuropathy that causes many social and occupational problems for individuals. The epidemiology of the disease has not been investigated in South Khorasan province; therefore, this study aimed to investigate the epidemiological and clinical symptoms and the relationship between the nerve and muscle findings of patients with CTS referred to the physical medicine clinic of Birjand University of Medical Sciences, Birjand, Iran, in 2023. In this descriptive and analytical study, 159 hands with CTS referred to the Physical Medicine Clinic of Imam Reza Birjand Hospital were examined in 2023. Demographic information, body mass index, history of previous diseases, dominant hand, affected hand, duration of involvement, and clinical symptoms, including night pain or pain during activity, numbness and tingling, and muscle atrophy of the thenar region were investigated, and recorded in the checklist. The severity of median nerve involvement in CTS syndrome was recorded using nerve conduction study and electromyography (NCS-EMG) with nemous electromyography divice and classifieds according to last guideline in Electrodiagnostic Medicine (2nd edition) book. The mean age of patients was 51.01±13.5 years, which was more common in women. It was more prevalent in the age group of 50-60 years. Numbness was the most common symptom. Frequency distribution of CTS severity had a significant relationship with age group, pain during sleep and work, paresthesia, and muscle atrophy (P<0.05). Necessary information should be given to health centers and housewives so that suspected patients can be referred to the centers for early treatment and prevention from the disease progression and additional burden on the health system.

Low levels of vitamin D are associated with clinical effects such as gastrointestinal disorders, cardiovascular disorders, autoimmune disorders, neuropathic diseases, cancer and metabolic syndrome. Carpal Tunnel Syndrome (CTS) is the most common cause of compression neuropathy, which has recently been linked to vitamin D deficiency in the onset or severity of symptoms. Therefore, this study was performed to evaluate the serum levels of vitamin D in patients with carpal tunnel syndrome.

This case-control study was performed on 100 patients referred to the neurology clinic of Ayatollah Rouhani Hospital with clinical symptoms of CTS for at least 3 months and 100 patients as a control group who referred to the same clinic for nerve conduction velocity test and did not show symptoms of CTS in clinical examination and electrophysiology. Patientschr('39') function, disease severity and pain were measured based on the Boston Carpal Tunnel Questionnaire (BCTQ). Serum vitamin D levels were also measured and compared between the two groups.

The mean age of patients was 43.53±10.68 years and controls were 45.48±7.12 years. The mean serum vitamin D levels in patients and controls were 19.18±11.39 ng/dL and 21.39±15.93 ng/dL, respectively. In controls, 57 women suffered from vitamin D deficiency (p<0.05). There was no significant difference between the two groups in terms of disease severity, function status, pain severity, electrophysiological defect, involved hand, dominant hand and symptoms associated with vitamin D deficiency and there was a negative correlation in vitamin D levels with disease severity, function and pain of patients.

The results showed that there was a relationship between serum vitamin D levels and gender. In addition, a negative correlation was observed between serum vitamin D levels and patientschr('39') disease severity and function and electrophysiological defects.