جستجوی مقالات مرتبط با کلیدواژه "نوکاردیا آستروئیدس" در نشریات گروه "پزشکی"

A 34-year-old woman with systemic lupus erythematosus who had two kidney transplants and 4 months after the second transplant, with symptoms of fever, malaise, night sweats and chest pain was referred to Al-Zahra hospital. In lung CT scan results of this patient lesion similar fungus ball was seen and for this patient was diagnosed fungal infection. Due to loss treatment, BAL samples were taken from patients and were sent to the microbiology laboratory. Based on microscopic and phenotypic test results patients diagnosed with pulmonary nocardiosis and According to antimicrobial susceptibility testing was treated by the drug co-trimoxazole. Nocardiosis opportunistic infection in immunocompromised patients is one of the main causes of death and should be properly diagnosed.

Nocardia asteroides complex is aerobic actinomycete, partially acid-fast and Gram –positive which rarely cause ocular infections especially in immunodeficient persons.
An 83-year-old man with diabetes presented with nasolacrimal duct obstruction to Labbafinejad Hospital Tehran –Iran. According to the clinical examination and microbial assessment cause of illness was diagnosed as Nocardia asteroides complex.
Diagnosis of Nocardia asteroides complex as a cause of nasolacrimal duct infection for prompt and proper treatment is effective.

Nocardia asteroides is gram-positive, partially acid-fast, aerobic actinomycetes which cause a wide range of skin infections, and pulmonary, cerebral, and ocular infection.
A 60-year-old man with diabetes presented with ocular ulcers in 2015. Through the medical records evaluation, physical examination, and biochemical evaluation of the patient, Nocardia asteroides complex was identified as the cause of infection. The patient was treated with amikacin and ciprofloxacin, and recovery was obtained and the patient was placed on the waiting list for corneal transplantation.
Diagnosis of keratitis caused by Nocardia asteroides is difficult and it may be misdiagnosed due similarities with keratitis caused by nontuberculous mycobacteria (NTM). Therefore, suitable diagnosis methods and early diagnosis of ocular nocardiosis are necessary. In the present study, Nocardia asteroides complex was isolated from a corneal ulceration.

Pulmonary nocardiosis is a dangerous chronic infection caused by implantation of aerobic actinomycetes called nocardia in respiratory system. The disease is more commonly found in patients with chronic infectious disorders, which may be treated by prolonged courses of antibiotics or corticosteroids, and in immunosuppressed patients. While pulmonary and systemic nocardiosis has no pathognomonic clinical or radiographic features it has the same clinical symptoms as tuberculosis, with a treatment much more different. The aim of this study was evaluation of nocardiosis among suspected pulmonary patients being confined or referred to Isfahan T.B center, in 2005. In this descriptive study 200 reliable samples, including 90 BAL (Bronchoalveolar lavage) and 110 sputum specimens, were collected during a period of 12 months from patients with diverse bronchopulmonary diseases, whether confined or referred to the center. %53.5 of patients were male and the rest were female. The data were statistically analyzed by SPSS Software using Fisher Exact Test. The results obtained through direct smears (KOH, BM, Kynion), culture and diagnostically - identical methods revealed eight positive cases (4%) of Nocardia Asteroids. Of 107 males, 6 (5.6%) and of 93 females, two (2.2%) were infected by Nocardia. There was no significant difference concerning age, sex, occupation, and nocardiosis.� Because of high incidence of nocardiosis found in this study, paying attention to nocardiosis in patients suffering from pulmonary diseases is highly recommended. Nocardiosis can become a severe infection which profoundly affects immunocompromised patients. Differential diagnosis often delays the time of diagnosis, which worsens the out come.

Group B Streptococcus (GBS) (Streptococcus agalactiae) is the leading cause of morbidity and mortality of newborn infants and accounted as a leading factor causing septicemia after birth in mothers. Infections in infants are usually acquired by contact with the genital tract of the mothers during labor and delivery. In two last decades, significant progress toward detection, prevention and treatment of pregnant women carrying GBS has been achieved. A rapid screening test for GBS that could accurately identify pregnant women carrying the bacteria at the time of delivery would obviate the need for prenatal screening. The standard method for the diagnosis of GBS colonization consists of culturing vaginal and anal secretions in a selective broth medium which inhibits the growth of other microorganisms. Today, it is accepted that PCR has a high sensitivity and specifically in diagnosis. The goal of this study was to screen pregnant woman carrying GBS by PCR. Samples were taken from anal and vaginal mucus of 125 pregnant women who were at 28-38 weeks of ingestion by swab. Samples were tested by standard culture using Todd Hewitt Broth and Blood Agar and also by PCR using primers specific for cfbgene. Culture identified 10 (8%) women as carriage of GBSout of 125 women tested. On the other hand, the PCR assay could identify 12 (9/6%) women positive for GBS. In comparison to culture results, sensitivity, NPV, specificity, and PPV of PCR were 100%, 100%, 98%, and 83%, respectively. The time required for PCR assay and culture were 2h and 36h,respectively. We found that GBS can be detected rapidly and reliably by a PCR assay using combined vaginal and anal secretions from pregnant women at the time of delivery. Also this study shows that the rate of incidence of GBS is high in Iranian pregnant women. We, therefore, recommend screening of pregnant women for detecting of GBS emphatically