جستجوی مقالات مرتبط با کلیدواژه "گیاه ختمی" در نشریات گروه "پزشکی"

Cadmium chloride causes hepatic dysfunction. In the present study, the protective effects of hydroalcoholic extract of Alcea rosea aerial parts were investigated on the hepatic enzyme dysfunction induced by cadmium chloride in adult male rats.

In this experimental study, 54 adult male Wistar rats were divided into six groups of 9 as follows; control group, sham group 1 received 0.2 ml/kg distilled water as a solvent, sham group 2 received 2 mg/kg cadmium chloride intraperitoneally for 21 days, and experimental groups 1, 2 and 3 received 2 mg/kg/day cadmium chloride intraperitoneally for 21 days and then respectively 150, 300 and 450 mg/kg hydroalcoholic extracts of aerial parts of Alcea rosea intraperitoneally for 30 days. At the end of the experiment, blood samples were taken from all animals to measure the levels of Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), Gamma-Glutamyl Transferase (GGT) and Lactate Dehydrogenase (LDH).

Mean serum concentrations of ALT, AST, LDH, and GGT in all experimental groups showed a significant decrease compared to the sham group 2. The mean serum concentrations of ALP in experimental groups 2 and 3 significantly decreased compared to the sham group 2 (P < 0.05).

The hydroalcoholic extract of the aerial parts of Alcea rosea probably modifies hepatic enzyme dysfunction induced by cadmium chloride in male rats.

Alcea rosea is on the list of medicinal plants with the potential for a serum lipid-lowering effect in patients with lipid disorder. Cadmium chloride causes lipid disorders. This study investigated the protective effects of hydroalcoholic extract of the aerial parts of Alcea rosea on serum lipid concentration disorders in male rats exposed to cadmium chloride

In this experimental study, 54 adult male Wistar rats were divided into 6 groups of 9. The control group, the sham group1 received 0.2 ml /kg distilled water as solvent. The sham group2 received 2 mg / kg cadmium chloride intraperitoneally for 21 days. Experimental groups 1, 2 and 3 respectively, received 2 mg / kg cadmium chloride intraperitoneally for 21 days and then 150, 300, and 450 mg / kg hydroalcoholic extracts of the aerial parts of Alcea rosea intraperitoneally for 30 days. Blood samples were taken from all animals at the end of the experiment to measure levels of HDL, LDL, total cholesterol and triglycerides. Data were analyzed through SPSS18 program, ANOVA and Tukey tests.

The mean serum concentrations of total cholesterol, triglyceride, and LDL cholesterol in all experimental groups compared to the sham group2 revealed a significant decrease. Mean serum HDL cholesterol concentration in experimental groups 3 also showed a significant increase compared to the sham group2 (p<0.05).

The hydroalcoholic extract of the aerial parts of Alcea rosea probably improves the lipid disorders caused by cadmium chloride in male rats.

As regards, about 80% of all latex allergy caused by latex gloves and the use of steroidsto treat this allergyis associated with local and systemic complications, therefore the research be necessary for treatment with fewer side effects. This study examined the impact of Alcea Althea on latex allergy in operating room personnel in hospitals of Arak city. This study was a double-blind clinical trial. Among operating staffs with allergies, samples were selected by simple random sampling. Then randomly divided into two: (intervention=33, control=33) groups. The intervention consisted of 5 mL topical solution from8%ofaqueous extract of Alcea Althea before and after the use of latex gloves for 30 days. Before and after intervention, samples were examined by a dermatologist. Samples completed self-assessment questionnaire of “Symptom Severity of Natural latex allergy”. The data were analyzed by SPSS 20 using Chi-square, Independent t-test, paired t-test and Analysis of Covariance. In this study, the mean age of staff was 32.45±6.69 in group control and 29.68±7.15 in intervention group. There was no significant different between groups in term of demographic. Results of this study showed that before intervention, severity of latex allergy symptoms between two groups didnt have any significant difference (P = 0.34), but after the intervention was seen significant difference (P= 0.013). Also before and after the intervention in control group, was not significantly difference in scores of symptoms severity of natural latex allergy (P= 0.11), however, for the control group was significantly difference (P= 0.008). According to Aqueous Extract of Alcea Althea reduce the symptoms of latex allergy, thus can be used as an effective herbal supplement helping to reduce the side effects of latex allergy.