جستجوی مقالات مرتبط با کلیدواژه « abdominal fat » در نشریات گروه « پزشکی »

Most polycystic ovary syndrome (PCOS) patients have metabolic abnormalities in which insulin resistance (IR) plays a pivotal role. Cinnamon is a herbal medicine with insulinotropic properties. This pilot study aimed to evaluate the effects of cinnamon on ovarian volume, androgenic profile, and metabolic and anthropometric parameters in women with PCOS. A single-center, double-blind, randomized, placebo-controlled trial was carried out on 39 overweight / obese women with PCOS. For six months, subjects in the cinnamon (500 mg) (n=19) and placebo (n=20) groups were given three capsules daily. Before and after the intervention, the variables were assessed. The data was analyzed using the GraphPad Prism software. After the intervention, the two intervention and control groups had significant differences in abdominal subcutaneous fat and ovarian volume, but they did not differ significantly in terms of body mass index (BMI). Also, after the intervention, no significant difference was observed between the two groups in terms of lipid profile and the concentration of androgenic biomarkers of insulin resistance. Cinnamon supplementation improves ovarian volume and subcutaneous abdominal fat but has no effect on anthropometric parameters, lipid profile, insulin resistance, or androgen hormones.

Two highly overriding problems that the society is facing today are stress and obesity. This narrative review article explains the vicious cycle of how stress leads to obesity and vice versa. Stress and obesity are interconnected to each other through different lines of cognition, behavior, and physiology. Stress can interfere with cognitive processes like self‑regulation. Stress can also influence behavior by indulging in overeating of foods that are high in calories, fat, and sugar. Stress also invigorates the generation of biochemical hormones and peptides, for example, leptin, ghrelin, and neuropeptide Y. This article also extracts the contribution of weight stigma and social stress in producing obesity in an obesogenic process. Recent Studies describe that psychological distress and elevated cortisol secretion promote abdominal fat, a feature of the metabolic syndrome, improvements in mindfulness, chronic stress, and cortisol awakening response (CAR) were associated with reductions in abdominal fat. Mindfulness intervention for stress suggests that mindfulness training improves eating patterns and the CAR, which may reduce abdominal fat over time. Obesity has a multifaceted etiology. In this review, several factors of stress are identified that affect the development of obesity. This review also provides valuable insight into the relationship between obesity and stress.

Different body composition indices may indicate various physiological statuses. The current study aimed at investigating the correlation between body composition indices (body mass index (BMI), body fat percentage (BFP), and abdominal fat) as well as physical and psychological symptoms of premenstrual syndrome (PMS). The current cross sectional study was conducted on 60 voluntary female students of Shiraz University (age: 18 - 25 years) in December 2016. Inclusion criteria were regular menstrual cycles, being single, no pregnancy, and no history of thyroid disease, polycystic ovaries, cancer, diabetes, and diagnosed psychiatric complications. Subjects completed Moos Menstrual Distress Questionnaire. Weight and height of subjects were recorded to calculate BMI, BFP and abdominal fat were calculated using the body composition analyzer. The Pearson correlation coefficient and regression analysis were used to analyze the data. The results of the current study revealed significant and positive correlation between BMI and physical symptoms of PMS (P = 0.045), BMI and psychological symptoms (P = 0.024), BFP and physical symptoms (P = 0.019), BFP and psychological symptoms (P = 0.023), abdominal fat and physical symptoms (P = 0.017), and abdominal fat and psychological symptoms of PMS (P = 0.049). The higher level of body composition indices were related to higher PMS symptoms and abdominal fat was the most important predictor for PMS symptoms.

Several surgical techniques have been so far used for treating Cerebrospinal Fluid (CSF) leakage (rhinorrhea) such as using abdominal fat or fascia lata, but these methods have complications such as the presence of several surgeons in variable fields in the operating room or cosmetic complications for donors such as the surgical scar. This study aimed to investigate using buccal fat pad for management of traumatic CSF leakage. Methods and Materials/Patients: In this clinical trial, 46 patients with traumatic CSF leakage were enrolled according to inclusion criteria and randomly divided into intervention and control groups. Buccal fat pad for the intervention and abdominal fat for the control were inserted in the defect of the anterior cranial cavity by applying endoscopic sinus surgery. The patients were followed up for 1 year postoperatively. All patients were improved with no recorded report of CSF leakage relapse. In the intervention group, temporary complications such as edema (18.2%), numbness (9.1%) and facial asymmetry (9.1%) were observed in resected buccal fat pad areas. Also the control group all developed abdominal scar. The duration of surgery in the intervention group was significantly shorter than control (P=0.02). Using buccal fat pad for management of CSF leakage is a highly effective and reliable method which requires simple procedure with low cosmetic complication and short duration of surgery compared with other methods such as an abdominal fat graft. In addition, using buccal fat pad has better cosmetic results, so we suggest this surgical method for patients with CSF leakage

Context: Non-alcoholic fatty liver disease (NAFLD) is a growing health problem in both developed and developing countries. Metabolic abnormalities, specially insulin resistance and hyperglycemia are highly correlated with NAFLD. Lifestyle modifications including physical activity and promoting nutrient intakes are critical in prevention and treatment of NAFLD. Hence, in this article we aimed to review the evidence regarding the effects of various macronutrients on fat accumulation in hepatic cells as well as the level of liver enzymes..Evidence Acquisitions: The relevant English and non-English published papers were searched using online databases of PubMed, ISI Web of Science, SCOPUS, Science Direct and EMBASE from January 2000 to January 2013. We summarized the findings of 40 relevant studies in this review.. Although a hypocaloric diet could prevent the progression of fat accumulation in liver, the diet composition is another aspect which should be considered in diet therapy of patients with NAFLD.. Several studies assessed the effects of dietary composition on fat storage in liver; however, their findings are inconsistent. Most studies focused on the quantity of carbohydrate and dietary fat; whilst there is very limited information regarding the role of protein intake..

To evaluate the association of apolipoprotein B (apoB), apolipoprotein A (apoA), and apoB/apoA ratio with the body fat indicators in patients with stable angina pectoris (SA). One hundred and twenty two participants aged 40-60 years old, with a mean age of 52.1 ± 7.2 years and SA, were recruited for the present study. Body weight, height, and waist circumference (WC) were measured, and waist to height ratio (WHtR) was calculated. After 12 hours of fasting, a blood sample was obtained and serum levels of apoB and apoA were measured and the apoB/apoA ratio was calculated. These patients underwent an abdominal computerized tomography scan (CTS) to assess visceral and subcutaneous adipose tissue (VAT, SAT). Linear regressions were computed to assess the relation of apoB, apoA, and their ratio with various measurements of adiposity (VAT, SAT, WC, and WHtR), with adjustment for age, sex, and BMI ≥ 25, WC ≥ 80 in women and WC ≥ 90 in men and WHtR ≥ 0.59. From totally 123 patients with SA with a mean age of 52.1 ± 7.2 years, 44.7% male and 55.3% women were entered. Significant positive associations were found between visceral fat area and the apoB/apoA ratio (P = 0.02, β = 0.2), and significant negative correlations were observed between visceral fat area and apoA concentrations (P = 0.04, β = −0.2). As abdominal fat accumulation is associated with other risk factors such as apolipoproteins in ischemic patients, then we most focus on control of these factors.

To investigate the association between obesity indices, abdominal fat distribution, and lipid profile in patients with stable angina (SA). Body weight, height, waist circumference (WC), body mass index (BMI), and waist /height ratio (WHtR) of 123 patients with SA who underwent coronary angiography were measured. Fasting blood samples were taken to measure the levels of fasting blood sugar (FBS), total cholesterol (TC), low- and high-density lipoprotein cholesterol (LDL-C, HDL-C), apolipoproteins A and B (apo A and apo B), and triglycerides (TG). According to angiography reports, the participants were divided into patients with or without coronary heart disease (CHD). All patients underwent an abdominal computerized tomography (CT) scan to measure the visceral, superficial, and deep subcutaneous fat. The mean ages of the patients with CHD (n = 73) and without CHD (n = 50) were 50.5 ± 7.6 and 53.7 ± 7.6 years, respectively (P = 0.03). The patients with CHD had significantly higher levels of TC, TG, and superficial subcutaneous fat, while the patients without CHD had higher levels of apo A (P ≤ 0.05). Multivariate analyses showed a significant association of visceral fat with TC, LDL-C, TG, and apo B, in the patients without CHD, while significant inverse associations were found between WC and HDL-C, WHtR, and apo A as well as visceral fat and LDL-C in the patients with CHD. Among anthropometrics and imaging indices of obesity, WC and WHtR have shown better association between central obesity with dyslipidemia in the patients with CHD, while CT-measured visceral adipose tissue area was the best correlate of dyslipidemia in the patients without CHD.

Adipose tissue as an endocrine organ secretes adiponectin that is a cardiovascular atherosclerosis-modulating factor. However, some studies showed that adiponectin reduces obesity. In the present study, adiponectin association with body mass index (BMI), waist circumference (WC), visceral adipose tissue (VAT) and subcutaneous visceral tissue (SAT) as different measurements of obesity were evaluated in patients with coronary heart disease (CHD). Sixty-eight patients with CHD were chosen using simple random sampling. Body weight, height, WC and blood pressure were measured. Fasting blood samples were taken to assess fasting blood sugar, total cholesterol, triglyceride, low and high-density lipoproteins cholesterol. Patients underwent an abdominal computerized scan (CTS) to detect VAT and SAT. Linear regression test used to assess the relation of different measurements of the obesity with adiponectin adjusting for age, sex, hypertension, dyslipidemia, and diabetes mellitus. The mean age of the study population was 50.5 ± 7.0. Females were 67.6% of study population. Multivariate analyses showed the inverse association of waist-to-height ratio (WHtR) (β = -0.25, p = 0.03), WC (β = -0.24, p = 0.24) and visceral fat (β = -0.32, p = 0.01) with adiponectin. WC and WHtR are simple proxy measures of obesity that better showed adverse metabolic effect of visceral fat in patients with CHD.

Epidemic levels of obesity and overweight in today's world are leading to a higher number of mortality and morbidity, especially due to cardiovascular diseases (CVDs). Body fat distribution contributes a great amount to atherosclerosis formation and therefore increased CVD incidence. The present study used the autopsy of 40 healthy-appearing adults who died due to non-cardiac causes to explore the association between atherosclerosis and body fat distribution indices including abdominal fat, visceral fat, subcutaneous fat, and pericardial fat. This cross-sectional study examined the autopsy of 40 individuals of 20 to 50 years old who died due to non-cardiac causes, mostly car accidents, and were sent to the forensic center. Measurement of abdominal fat, visceral fat, subcutaneous fat and heart weight/height ratio as a pericardial fat index in the cadavers was followed by atherosclerosis assessment in the carotid artery, left and right internal and external carotid arteries, as well as right coronary artery (RCA), left anterior descending (LAD) and left circumflex (LCX) coronary arteries based on American Heart Association (AHA) criteria. In order to evaluate the relation between atherosclerosis development and body fat distribution indices, SPSS version 19 was used for multinomial logistic regression analysis in the crude and adjusted models (for age, smoking, LDL-c, HDL-c, HBA1c, and CVD history). The effectiveness of body fat distribution variables along with age, smoking, LDL-c, HDL-c, HBA1c, and CVD history on atherosclerosis was also determined by stepwise forward regression analysis. The average age of the subjects was 29.97 ± 9.84 years. Among 40 performed autopsies only 3 were women. Coronary and carotid atherosclerosis were observed in 50% and 85% of the cadavers, respectively. Logistic regression analysis revealed no link between carotid atherosclerosis and body fat distribution indices. Although, the correlation found between heart weight/height ratio and atherosclerosis in the crude model did not remain significant after the adjustment of other indices, stepwise forward regression analysis resulted in OR = 9.461 and confidence interval = 1.199-74.650. Our results indicated a link between coronary atherosclerosis and heart weight/height ratio. Since coronary and carotid atherosclerosis were not found to be correlated with subcutaneous and visceral fat, further investigation is suggested.