جستجوی مقالات مرتبط با کلیدواژه "amorphous calcium phosphate" در نشریات گروه "پزشکی"

This study aimed to assess the shear bond strength (SBS) of molar tubes to the enamel surface of molar teeth using a resin-modified glass ionomer (RMGI) cement modified with amorphous calcium phosphate (ACP).

In this in-vitro study, 60 extracted human third molars were randomly divided into four groups for bonding of molar tubes to the enamel surface. Fuji Ortho LC and Fuji Ortho LC modified with ACP (1.55 wt%) were used in groups 1 and 2, respectively. In group 3, the enamel surface was sandblasted, and bonding was then performed using Fuji Ortho LC glass ionomer modified with ACP. In group 4, molar tubes were conventionally bonded using Transbond XT composite. The SBS was measured using a universal testing machine.

The mean SBS of groups 1 to 4 was 10.22, 6.88, 9.4, and 13.68 MPa, respectively. Only the SBS of group 1 was not significantly different from that of groups 3 and 4 (P>0.05). Comparison of adhesive remnant index (ARI) scores of the groups revealed significant differences only between groups 1 and 4 (P<0.001) and between groups 1 and 2 (P=0.002).

The results revealed that the addition of ACP to Fuji Ortho LC significantly decreased the SBS of molar tubes bonded to enamel compared to the conventional resin bonding system. Sandblasting of the enamel surface significantly increased the bond strength. Fuji Ortho LC modified with ACP is recommended for bonding of molar tubes to posterior teeth considering its cariostatic property.

Context: One of the most important aspects of dental profession is to consider the effectiveness of the preventive systems applied and maintain the good oral hygiene, oral health and minimize the risk of caries among the patients. A great spectrum of preventive activities and materials like fluoride applications, fissure sealants; also new technologies like Casein Phosphopeptide-Amorphous calcium phosphate (CCP-ACP) have a wide effect on preventing caries.
The objective of this systematic review with meta-analysis was to review systematically the clinical trials of CPP-ACP complex and determine the caries preventive effects on the remineralization process.
Data Sources: PubMed, Google Scholar, biomed central, cochrane oral health reviews, Cochrane library, directory of open access journals, Ovid Medline, Web of science and EMBASE were searched up to February 2016. Only articles in English were included. Trials that were considered clinically and methodologically homogeneous and reported on similar outcomes were pooled for meta-analyses. The clinical studies that inspected the effects of casein derivatives in dental practice were included. In vitro studies, case reports, case series, letters to the editors, editorials, review articles and commentaries were not included for the statistical analysis but evaluated to identify the potential outcomes of the further studies.
Study Selection: Of the 3859 studies screened 92 studies were assessed for eligibility, and 22 were selected for inclusion and 11 was in the final sample for meta-analysis. Systematic review was assessed and the remineralization effect of CPP-ACP was demonstrated compared to placebo in the meta-analysis.
The evaluated systematic review with meta-analyses, clinical trials showed the remineralization effect of CPP-ACP on early caries lesions mainly the white spot lesions (WSL’s). In vivo RCT studies reveal a promising caries preventing effect, inducing remineralization and treating dentin hypersensitivity and dry mouth with the use of clinical CPP-ACP application.

The aim of this study was to evaluate and compare the retentive strength of orthodontic bands cemented with amorphous calcium phosphate (ACP)-containing and conventional glass ionomer cements (GICs).
One-hundred-and-twenty mandibular third molars were embedded in acrylic resin blocks with the buccal surface of crowns perpendicular to the base of the mold. The teeth were randomly divided into four groups containing 30 teeth each. Groups 1 and 3 were cemented using conventional GIC and groups 2 and 4 were cemented using ACP-containing orthodontic cement. Groups 1 and 2 without thermocycling, and groups 3 and 4 after thermocycling (5000 cycles, 5° to 55°C) were tested for retentive strength using a universal testing machine (crosshead speed of 1mm/minute). Two-way ANOVA was performed to compare the retentive strength of the groups.
The highest retentive strength belonged to group 1, and it was significantly higher than that of group 2 (P Although retentive strength decreased when ACP was added to GIC, the retentive strength of the samples cemented by ACP-containing GIC was remarkably high after thermocycling. It seems that in the oral cavity, ACP-containing GIC provides sufficient strength to endure forces applied on posterior teeth.

Despite widespread clinical uses of resin-modifi ed glass-ionomers (RMGIs), their sealing ability is still a concern. This study evaluated the effect of delayed light activation (DLA) of RMGI on marginal sealing in differently pretreated cavities. In this in vitro study, two standardized Class V cavities were prepared on the buccal and lingual surfaces of 56 sound maxillary premolars at the cementoenamel junction. The cavities were randomly divided into eight equal groups. In groups 1-4 (immediate light activation [ILA]), no pretreatment (negative control [NC]) and three surface pretreatments were used, respectively as follows: Cavity conditioner, Vitremer primer, cavity conditioner plus and casein phosphopeptideamorphous calcium phosphate (CPP-ACP). Fuji II LC (GC, Japan) was prepared and placed in the cavities and immediately light-cured according to manufacturer’s instructions. In groups 5-8 (DLA), the same pretreatments were applied, respectively. After placing Fuji II LC in the cavities, the restorations were light-cured after a 3-min delay. After fi nishing the restorations, the specimens were placed in water for 1-week and thermocycled. Microleakage scores were determined using the dye penetration technique. Kruskal–Wallis test and Mann–Whitney U-test were used to analyze the obtained data (α = 0.05). At the dentin margins, DLA resulted in a lower microleakage for no treatment (NC), cavity conditioner and cavity conditioner plus ACP-CPP pretreatments groups (P ≤ 0.004); however, no difference was observed for Vitremer group (P > 0.05).At the enamel margins, no difference was observed between DLA and ILA for all groups (P > 0.05); only NC group exhibited a lower microleakage in case of DLA (P = 0.007). Delayed light activation of RMGI may lead to different effects on marginal sealing, depending on pretreatment procedures used in the cavity. It might improve dentin sealing when no treatment and conditioner alone or with CCP-ACP is used.

Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is applied for remineralization of early caries lesions or tooth sensitivity conditions and may affect subsequent resin bonding. This in vitro study investigated the effect of CPP-ACP on the shear bond strength of dental adhesives to enamel. Sixty extracted human molar teeth were selected and randomly divided into three groups and six subgroups. Buccal or lingual surfaces of teeth were prepared to create a fl at enamel surface. Adhesives used were Tetric N-Bond, AdheSE and AdheSE One F. In three subgroups, before applying adhesives, enamel surfaces were treated with Tooth Mousse CPP-ACP for one hour, rinsed and stored in 37°C temperature with 100% humidity. This procedure was repeated for 5 days and then adhesives were applied and Tetric N-Ceram composite was adhered to the enamel. This procedure was also fulfi lled for the other three subgroups without CPP-ACP treatment. After 24 hour water storage, samples were tested for shear bond strength test in a universal testing machine. Failure modes were determined by stereomicroscope. Data were analyzed by t-test and one-way analysis of variance with P < 0.05 as the level of signifi cance. In comparison between applied and non-applied CPP-ACP subgroups, there was no signifi cant decrease in the shear bond strength to enamel only in Tetric N-Bond (P > 0.05). In nonapplied CPP-ACP subgroups, there were statistically signifi cant differences among all subgroups. Tetric N-Bond had the highest and AdheSE One F had the lowest shear bond strength. CPP-ACP application reduces the shear bond strength of AdheSE and AdheSE One F to enamel but not Tetric N-Bond.

Dental caries is associated with oral pathogenes and Streptococcus mutans (S. mutans)is one of the primary cariogenic organisms. The aim of this clinical study was to evaluate the effect of sugar free chewing gum containing casein phosphopeptide-amorphous calcium phosphate(CPP-ACP) and Xylitol on salivary Streptococcus mutan. 60 dental students, who volunteered after signing an informed consent, were randomly allocated to receive one of the following interventions: (A) Chewing gum containing CPP-ACP, (B) Chewing gum containing Xylitol. Subjects within the experimental groups chewed gum for 20 minutes, three times a day after meals for 3 weeks. Pre- and post-intervention unstimulated saliva samples were quantified for Streptococcus mutans count. A statistically significant reduction (p<0.05) of salivary S. mutans was displayed in both groups A and B after the intervention. When results compared with baseline, and group A shows more statistically significant reduction of salivary S. mutans than group B. In conclusion, daily chewing gum containing CPP-ACP and xylitol reduce the level of salivary S. mutans in a significant way, but chewing gum containing CPP-ACP can reduce the level of salivary S. mutans in a significant way than Xylitol chewing gum.