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عضویت

جستجوی مقالات مرتبط با کلیدواژه « aromatic water » در نشریات گروه « پزشکی »

  • مصطفی پیرعلی همدانی، هدیه یوسفی، فاطمه تاج آبادی، زهرا توفیقی، عباس حاجی آخوندی، سعید گودرزی*
    مقدمه

    گیاهان جنس Scutellaria، با نام عمومی skullcap و با نام فارسی بشقابی شناخته می شوند. این گیاهان متعلق به خانواده Lamiaceae یا نعناییان هستند. در ایران 22 گونه از جنس بشقابی وجود دارد که 10 گونه از آنها بومی ایران است. گیاهان این جنس دارای اثرات متعددی از جمله محافظت کننده عصبی، محافظت کننده کبد، ضدسرطان، ضدمیکروبی، ضدویروسی و آنتی اکسیدانی هستند. همچنین در شرایط بی خوابی و زوال عقل موثر هستند.

    هدف

    هدف از این مطالعه بررسی ترکیب اسانس ها و عرق های برخی از گونه های بومی بشقابی ایران بود.

    روش بررسی

    قسمت های هوایی گیاه بشقابی سنبله ای (Scutellaria pinnatifida) با زیرگونه های مختلف viridis، mucida و alpine و گونه های بشقابی جنگلی (Scutellaria pinnatifida) و بشقابی نمدین (Scutellaria tomentosa) از مناطق مختلف ایران جمع آوری شدند. اسانس و عصاره هگزانی عرق های گیاهان منتخب در این جنس به روش تقطیر با آب و توسط دستگاه کلونجر به دست آمد و سپس توسط دستگاه GC-MS مورد تجزیه و تحلیل قرار گرفت.

    نتایج

    نتایج این مطالعه نشان داد که ترکیبات جرماکرن- د، مشتقات کاریوفیلن و لینالول در اسانس این گیاهان به وفور یافت می شود. ترپنوییدهای اصلی موجود در عرق این گیاهان، لینالول و ترکیب 1-اکتن-3 -ال بود.

    نتیجه گیری

    نتایج حاصل از آنالیز اسانس ها و عرق های گونه های مختلف بشقابی نشان داد که عوامل جغرافیایی مانند ارتفاع، فصل جمع آوری گیاهان و... می تواند بر تولید متابولیت های ثانویه گیاهی موثر باشد.

    کلید واژگان: بشقابی, اسانس, عرق, لینالول, کاریوفیلن, جرماکرن- د}
    Mostafa Pirali Hamedani, Hediye Yousefi, Fateme Tajabadi, Zahra Tofighi, Abbas Hadjiakhoundi, Saied Goodarzi*
    Background

    Plants of the genus Scutellaria, commonly known as skullcap, belong to the Lamiaceae family. There are 22 species of Scutellaria in Iran, 10 species of which are native to Iran. Plants of this genus have several effects including neuroprotective, hepatoprotective, anti-cancer, antimicrobial, antiviral, and antioxidant. They are also effective in insomnia and dementia conditions.

    Objective

    The aim of this study was to investigate the composition of essential oils and aromatic waters of some native Scutellaria species from Iran.

    Methods

    Aerial parts of Scutellaria pinnatifida with different subspecies such as mucida, viridis, and alpina, Scutellaria tournefortii, and Scutellaria tomentosa were collected from different regions of Iran. The essential oils and hexane extracts of aromatic waters of selected plants in this genus were obtained by hydrodistillation with clevenger type apparatus and analyzed by GC-MS.

    Results

    The results of this study showed that germacrene D, caryophyllene derivatives and linalool are found in abundance in the essential oils of these plants. The main terpenoids in the aromatic waters of these plants were linalool and 1-octen-3-ol.

    Conclusion

    The analysis of the essential oils and aromatic waters of Scutellaria species demonstrated that different geographical factors such as altitude and the season of plant collection can be effective on the production of plant secondary metabolites.

    Keywords: Scutellaria, Essential oil, Aromatic water, Linalool, Caryophyllene, Germacrene D}
  • Ali Arabi Monfared, Maryam Yazdanpanah, Zahra Zareshahrabadi, Keyvan Pakshir, Mehdi Ghahartars, Davood Mehrabani, Samira Yazdanpanah, Aida Iraji, Kamiar Zomorodian *
    Background and Purpose

    In Iranian culture, aromatic waters harboring a slight amount of essential oil have been popularly used for many years as a pleasant non-alcoholic drink with various medicinal properties.In this study, chemical composition of Zataria multiflora Boiss. (ZM) aromatic water was determined and its in vitro and in vivo antifungal properties were investigated.

    Materials and Methods

    Chemical composition of the essential oil extracted from aromatic water (AW) of ZM was analyzed by Gas chromatography and gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the AW against Candida species was determined by broth micro-dilution methods. Additionally, biofilm formation inhibition and antioxidant activity of the AW were measured using XTT reduction and DPPH methods, respectively. Antifungal activities of the AW in the prevention and/or treatment of gastrointestinal (GI) candidiasis in animal models were also evaluated.

    Results

    The GC-MS analysis revealed that the major constituents of ZM AW were Carvacrol (46.56%) and Thymol (40.67%). The ZM AW inhibited the growth and biofilm formation of Candida species in the range of 0.25-0.5 V/V. Moreover, ZM AW significantly decreased Candida colonization in therapeutic groups (P<0.05).

    Conclusion

    Given the wide therapeutic potential of ZM AW, including antifungal and antioxidant activities, it might be possible to use it in the management of mucocutaneous or alimentary candidiasis.

    Keywords: aromatic water, Antifungal property, candida albicans, Essential oil, Zataria multiflora Boiss}
  • Ali Arabi Monfared, Seyyed Amin Ayatolahi Mousavi, Kamiar Zomorodian *, Davood Mehrabani, Aida Iraji, MahmoodReza Moein
    Background and Purpose

    Aromatic waters (AWs) are therapeutic distillates, which harbor both essential oil and water-soluble components of a plant. Due to the dispersion of the light amount of essence through the AWs, they have their specific pleasant smell, taste, and medicinal properties. In Iranian traditional medicine, Trachyspermum ammi AW is used to treat gastrointestinal disorders. The present study was conducted to determine the chemical composition of the essential oil extracted from T. ammi AW and its antifungal activities against Candida species.

    Materials and Methods

    The composition of the essential oil extracted from T. ammi AW was analyzed by gas chromatography-mass spectrometry. In addition, the evaluation of the antifungal activity of AW against Candida species was performed using broth microdilution methods as recommended by the Clinical Laboratory Standard Institute. Moreover, the biofilm formation inhibition, antioxidant properties, and experimental activity of AW were determined in an animal model.

    Results

    According to the results, thymol (78.08%) was the major compound of EO, followed by carvacrol (8.20%) and carvotanacetone (6.50%). Furthermore, T. ammi AW exhibited antifungal activities against the examined fungi and inhibited the biofilm formation of C. albicans at a concentration of up to 0.25 V/V. Histopathological analyses revealed that Candida colonization declined in the mice following the administration of T. ammi AW in a therapeutic trial.

    Conclusion

    It seems that the presence of phenolic monoterpenes in AW has resulted in antifungal effects. Pleasant odor and antioxidant properties are extra bonuses to the antimicrobial effects of this plant. Based on the findings, AW might have the potential to be used in the management of alimentary candidiasis or oral hygienic products.

    Keywords: Antifungal activity, aromatic water, Biofilm, Candida, Candidiasis, Trachyspermum ammi}
  • Reza Heidari, Akbar Raeisi, Ardalan Pasdaran, Azadeh Hamedi *
    Oriental plane hydrosol (distillate), as a remedy for weight gain and asthma treatment is popular in ethnomedicine. Phytochemicals of medicinal plants could have side effects or serious damages. In this study, the oriental plane hydrosol was prepared by steam distillation. Also, tree oriental plane hydrosol samples from different companies were purchased from herbal market to compare the constituents. The phytochemicals in hexane and chloroform extracts of the hydrosols were identified by GC-MS analysis. In order to investigate subacute toxicity, the hydrosol was given to groups of 6 of male mice at doses of 10, 50, 100, 300 or 500 µl/ mouse/ twice a day by gavage for 14 consecutive days (subacute toxicity) or just for one day (acute toxicity). Serologic and pathologic samples were prepared. Chloroform extracts contained mostly (Z) -3-hexenol, thymol, carvacrol, camphor and the main constituents of hexane extracts include decane, dodecane and hexadecane. The results showed lack of serologic toxicity in subacute consumption of the hydrosol. In acute toxicity study, the levels of ALT, LDH, and BUN increased significantly. Other enzymes did not change significantly in compare to the control group. No significant pathologic damage was seen in heart or lung tissues, but the liver and kidney showed mild inflammation in acute toxicity study and inflammation in subacute toxicity studies. Determination of compounds which are responsible for the observed effects and especially safety of this hydrosol consumption for the longer periods can prevent side effects or possible toxicities.
    Keywords: Aromatic water, Oriental Plane Distillate, Platanus orientalis, Toxicity}
  • مونا غیاثی یکتا، فرحناز خلیقی سیگارودی*، خدیجه دیده‎بان افشرد، فرزانه بهادری
    مقدمه
    جنس آویشن، گیاهانی چندساله و معطر بوده و متعلق به خانواده نعناعیان (Lamiaceae) می‎باشند. اسانس این گیاهان برای درمان التهاب‎های مخاط دهان و گلو، زکام و مشکلات تنفسی و نیز به عنوان آنتی‎اکسیدان و ضد‎عفونی‎کننده، استفاده می‎شود.
    هدف
    هدف از این مطالعه، مقایسه‎ی ترکیبات شیمیایی اسانس حاصل از عرق سه گونه آویشن کاشته شده در سمنان و نیز ارزیابی خاصیت آنتی اکسیدانی عرق و اسانس حاصل از عرق آنها بود. این سه گونه در ساخت عرق آویشن، در بازار ایران کاربرد دارند.
    روش بررسی
    در این مطالعه اندام‎های هوایی سه گونه گیاه کاشته شده آویشن باغی، آویشن دنایی و آویشن کوهی، از مزرعه تحقیقاتی منابع طبیعی استان سمنان جمع آوری شدند. ابتدا عرق گیاهان خشک شده توسط روش تقطیر با آب ، استخراج شد و سپس با استفاده از پنتان، روغن ‎فرار این عرقیات، جدا شده و بوسیله دستگاه گاز کروماتوگرافی متصل به طیف‎سنج جرمی (GC/MS) مورد تجزیه و تحلیل قرار گرفت. سپس خاصیت آنتی اکسیدانی عرق و اسانس حاصل از عرق، به روش سنجش فعالیت روبش رادیکال DPPH مورد ارزیابی قرار گرفتند.
    نتایج
    تیمول ترکیب اصلی اسانس حاصل از عرق دو گونه آویشن‎ باغی و آویشن دنایی (به ترتیب با 36/38 درصد و 82/56 درصد) بود، در حالی که آلفا- ترپینیل استات با 06/31 درصد، ترکیب اصلی اسانس حاصل از عرق گیاه آویشن ‎کوهی بود. بیشترین فعالیت آنتی‎اکسیدانی در اسانس و عرق آویشن دنایی مشاهده شد.
    نتیجه گیری
    ترکیبات شیمیایی اسانس حاصل از عرق سه گونه آویشن که در ساخت عرقیات موجود در بازار به کار می‎روند با یکدیگر متفاوت بوده و می‎تواند در اثربخشی عرق تاثیرگذار باشد.
    کلید واژگان: آویشن باغی, آویشن دنایی, آویشن کوهی, آنتی اکسیدان, اسانس, عرق, GC-MS}
    M Ghiaci Yekta, F Khalighi, Sigaroodi*, Kh Didehban, F Bahadori
    Background
    The genus Thymus is a perennial and aromatic plant and belongs to Lamiaceae family. The essential oils of these plants are used for the treatment of mouth and throat mucosal inflammation, catarrh and respiratory disorders and as antioxidant and antiseptic.
    Objective
    The purpose of this study was to compare chemical composition of the essential oils derived from aromatic waters of three thyme species cultivated in Semnan and to investigate the antioxidant properties of aromatic waters and the essential oils. These three species are used in manufacturing of thyme aromatic water in Iranian market.
    Methods
    In this study, aerial parts of three cultivated species, Thymus vulgaris, Thymus daenensis and Thymus kotschyanus were collected from Semnan natural resources research field in Shahmirzad. At first, the aromatic waters of dried plants were extracted by water distillation method, and then the essential oils of the aromatic waters were isolated using pentane and analyzed by GC/MS. Then antioxidant activities of thyme waters and the derived essential oils were evaluated by DPPH radical scavenging method.
    Results
    Thymol was the major component of the derived essential oils of two species Thymus vulgaris (38.36 %) and Thymus daenensis (56.82 %), while α-terpinyl acetate (31.06 %) was the main ingredient of the essential oil of Thymus kotschyanus. The most antioxidant activity was observed in the essential oil and aromatic water of Thymus daenensis.
    Conclusion
    Chemical composition of the essential oils derived from aromatic water of three thyme species used in manufacturing of thyme water in Iranian market were completely different and it can affect the effectiveness of aromatic thyme water.
    Keywords: Thymus vulgaris, Thymus daenensis, Thymus kotschyanus, Essential oil, Aromatic water, GC-MS, Antioxidant}
  • Bita Shahpar *, Mahmoodreza Moein, Mohammad M. Zarshenas

    Current study aimed to chemically assess volatile constituents of eleven commercial cinnamon hydrosols purchased from Fars province (Iran) local markets in comparison to a standard sample. Via a liquid extractor, the volatile oil fractions of samples and also the standard hydrosol yielded from essential oil extraction of an authenticated cinnamon bark sample were recovered. Gas chromatography/ flame ionization detector (GC/FID) and subsequently GC/MS (GC/mass spectroscopy) were employed to assess and identify the chemical compositions of prepared samples. The procedure of analysis revealed in the appearance of totally 25 components. Cinnamaldehyde was found as the main constituent in ten populations (S2-S11) as well as in the standard sample (63.04-91.61%). Considerable amounts of Dibutyl phthalate, as a commonly used plasticizer was also detected in all samples. This is the first report of analysis and identification of volatile constituent in cinnamon hydrosol, a common medicinal beverage. Although, high amount of Cinnamaldehyde in cinnamon hydrosol can introduce this tasty medicinal beverage for further studies similar to the respective botanical part or various usual extracts, more comprehensive monitoring is to be performed on safety, purity and quality of such preparation.

    Keywords: Aromatic water, Cinnamomum verum J.Presl, GC, MS, Hydrosol, Volatile constituent}
  • Abdolhossein Miri, Hamid Reza Monsef-Esfahani, Mohsen Amini, Yaghoub Amanzadeh, Abbas Hadjiakhoondi, Reza Hajiaghaee, Atefeh Ebrahimi
    The essential oils and aromatic water, known as Arak in traditional Iranian medicine, comes from the aerial part of Teucrium persicum Boiss., which is grown in Fars Province located in Iran. The samples were collected in summer and the oils and aromatic water were obtained through steam distillation. The chemical composition of the oils was analyzed using GC-MS. An analysis of the chemical profile of the isolated oils revealed the presence of more than 80 compounds, mainly oxygenated monoterpenes and sesquiterpene hydrocarbons. The principal components of essential oil were α-cadinene (9.7%), 1,4-cadinadiene (9.2%) and α-terpinyl acetate (7.9%). The major constituents in the Arak were determined to be linalool (10.4%), α-cadinene (7.5%) and γ-terpineol (7.3%). Most of the compounds identified from different oils were similar, but their amounts differed. The oil revealed a higher content of total phenolics than the Arak (1.71 ± 0.12 mg GAE/g DW and 1.36 ± 0.11 mg GAE/g DW, respectively). The antioxidant activity of the oils was calculated by using a ferric reducing antioxidant power assay (FRAP), DPPH radical scavenging activity, and a reducing power assay (RP). The FRAP value points to a considerably higher reducing power of essential oil (220 ± 7.2 µmol Fe2+/g DW) compared to that of Arak (113 ± 5.4 µmol Fe2+/g DW). Essential oil exhibited higher radical scavenging potential (IC50 = 0.29 mg/mL) than Arak (IC50 = 4.19 mg/mL). The reducing power of essential oil (51.7 ± 4.3 µg BHA/g DW) was higher than that of Arak (34.1 ± 2.7 µg BHA/g DW). The studied essential oils showed good antioxidant activities, which were higher than those of Arak.
    Keywords: Teucrium persicum Boiss, Antioxidant properties, Arraq, essential oils, Aromatic water}
نکته
  • نتایج بر اساس تاریخ انتشار مرتب شده‌اند.
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