جستجوی مقالات مرتبط با کلیدواژه « bedsore » در نشریات گروه « پزشکی »

Since the prevalence of pressure ulcers has been increasing in recent years, they need a new and efficient treatment. The pleiotropic effects of statins can be used for this purpose. This study aimed to evaluate the appropriate formulation of 3% simvastatin (SIM) topical cream and its effect on the healing of bedsores. At first, the appropriate formulation of SIM topical cream was investigated. In a randomized, double-blind trial, 42 patients were divided into two groups: placebo and SIM cream, and used these creams for three weeks, once every 12 hours on a clean bedsore. Bedsore dimensions were measured at the beginning and end of the study. Seventy-seven percent of patients in the SIM group and 35% in the placebo group had more than 20% healing of bedsores. Age (P=0.03), gender (P=0.01), statin use (P=0.04), and diabetes (P=0.04) had statistically significant impacts on bedsore healing. Also, better wound healing in the non-diabetic patients was observed. It seems that the topical cream of SIM significantly affects the healing of bedsores and can also be used in bedsores of diabetic patients. In diabetic patients with bedsores, blood sugar control through nutritional counseling and consumption of regular diabetic medication seems to be very effective and efficient.

Bedsores are caused by decreased tissue perfusion due to prolonged pressure on the skin and represent one of the problems of immobilized patients, including hospitalized ones. This study reports the successful treatment of a patient with bedsore wounds using the larvae of the fly Lucilia sericata. The study focused on a 64-year-old man residing in Qom (a city in central Iran), who was hospitalized for 45 days at Qom Shahid Beheshti Hospital in November 2019 because of cardiovascular disease and chronic obstructive pulmonary disease (COPD). He had a pressure ulcer of about 9.5 cm in diameter on the skin overlying the sacrum. After showing resistance to honey dressing and conventionalantibiotic treatments, maggot therapy was recommended. This procedure was done by releasing the larvae of L. sericata 12 times every three days. The removal of necrotic tissues and the appearance of the granulated tissues were recorded using a ruler as an indicator of healing. After 12 sessions of larval treatment, the wound surface considerably reduced and was finally healed. Thus, it can be argued that maggot debridement therapy (MDT) is an effective treatment for bedsores and can be recommended to physicians as an adjuvant treatment for complex and resistant ulcers.

For patients with prolonged bed rest and immobilization because of motor or consciousness disorders, many factors may contribute to the development of pressure ulcers. To this end, the present study aimed to investigate the frequency of pressure ulcers and the factors affecting the development of this condition in intensive care units (ICUs).

In this descriptive cross-sectional study, the case files and records of patients hospitalized between March 2017 and March 2018 entered the study using the census method. The necessary information including age, gender, location of pressure ulcers, number of ulcers on each part of the body, length of stay in ICU, and underlying diseases was extracted from the files and recorded in the data checklist. In the end, the extracted data were analyzed with SPSS 25.

Of the 781 patients studied, 71 (9.1%) had pressure ulcers, of whom 34 were men and 37 were women. A statistically significant difference was found between men and women in terms of the incidence of pressure ulcer (p = 0.0013). The most common sites of pressure ulcers were buttock with 34 cases (47.9%) and sacrum with 21 cases (29.6%).

Old age and prolonged stay in ICU are important determinants of the development of pressure ulcers.