جستجوی مقالات مرتبط با کلیدواژه "chronic osteomyelitis" در نشریات گروه "پزشکی"

Chronic osteomyelitis is a severe and persistent condition that engages bone and bone marrow. The infection can be limited to the bone, or it can propagate to the bone marrow, the periosteum, and the surrounding soft tissues. It represents a major financial every health system and impacts the quality of life of the affected patients. Diagnosing chronic osteomyelitis remains difficult. Accordingly, laboratory and imaging studies are necessary in this respect. A 49-year-old man after high energy trauma underwent debridmant and fixation. After 3 years’ patient admitted in infection ward with fever presentation. The clinical examination didnchr('39')t reveal any sign of localization of fever. Chronic osteomyelitis is not always associated with fever in this situation Other diagnoses should be considered after role out other disease osteomyelitis.

Traditionally, the management of chronic osteomyelitis emphasizes the excision of necrotic and infected material (sequestrectomy/debridement) followed by prolonged administration of antibiotics. Most children with chronic osteomyelitis undergo surgery with the inherent risk of damage to their growth plate. Treatment regimen based on findings of imaging with emphasis on antibiotics to potentially reduce the rate of surgical interventions is being increasingly reported. An 8-year-old thin built Indian boy belonging to lower socio-economic group presented to the orthopedic department with the chief complaints of pain in the left upper leg for the last 3 months. Radiograph of the affected limb showed features of chronic osteomyelitis with a large diaphyseal sequestrum on the medial cortex of tibia with incomplete involucrum. No surgery was performed; not even incision and drainage. The sinuses healed completely in 6 weeks time with appropritate antibiotics alone. Gradually, over a period of 8 months, the large tibial diaphyseal sequestrum got fully incorporated into the healthy diaphyseal bone indistinguishable from normal bony architecture with complete clinical remission of sepsis. Our rare case is an example of the evolving notion that antibiotics and supportive care alone may be sufficient enough in the treatment of chronic osteomyelitis even with large diaphyseal sequestrum in paediatric cases where excellent healing potential of the immune-competent child may potentially make surgical intervention redundant.

Small colony variants (SCVs) of Staphylococcus aureus often cause persistant and relapsing infections. SCVs are characterized by a strong reduction in growth rate, atypical colony morphology and unusual biochemical characteristics. We here report a case of chronic oesteomyelitis caused by SCV of Staphyloccous aureus in a middle aged male patient.