جستجوی مقالات مرتبط با کلیدواژه "coat's disease" در نشریات گروه "پزشکی"

To present a case of linear scleroderma known as “en coup de sabre” associated with Coats’- like response.

A 12-year-old boy presented with subacute painless vision loss in the ipsilateral side of the patient’s en coup de sabre lesion. Ocular examination revealed vitreous hemorrhage with severe exudation of the posterior pole and telangiectatic vessels. Fundus fluorescein angiography indicated multiple vascular beadings and fusiform aneurysms with leakage which was consistent with a Coats’-like response. The patient was subsequently treated with intravitreal bevacizumab and targeted retinal photocoagulation. Twelve months’ follow-up showed marked resolution of macular exudation with significant visual improvement.

Physicians should be aware of the possible ophthalmic disorders accompanying en coup de sabre and careful ophthalmologic examinations should be performed in these patients. As presented in the current case, treatment with intravitreal anti-VEGF agents and laser photocoagulation may be a beneficial option for patients with coats’-like response.

To determine the types and frequency of ocular conditions simulating retinoblastoma (pseudo‑retinoblastoma) at Farabi Eye Hospital, Tehran, Iran. We reviewed data of patients who were referred with a diagnosis of retinoblastoma to Farabi Eye Hospital oncology clinic, from January 2009 to July 2013. Examination under general anesthesia was performed for all patients. Other investigations, such as ultrasonography, were performed as required. Of a total of 331 patients (aged 1‑60 months), 138 (42%) were found to be suffering from a benign disorder. Among these pseudo‑retinoblastoma cases, Coats’ disease was the most prevalent codition (n = 36, 26%); persistent hyperplastic primary vitreous (PHPV) and familial exudative vitreo‑retinopathy (FEVR) were the next two common pseudo‑retinoblastoma cases in our series. The rate of misdiagnosis upon referral to our center was close to 40%. The most common pseudo‑retinoblastomas entities include Coats’ disease, PHPV and FEVR. An accurate diagnosis is essential for management of pseudo‑retinoblastoma cases.