جستجوی مقالات مرتبط با کلیدواژه « cochlear » در نشریات گروه « پزشکی »

انتخاب همه

Effect of Different Blood Groups on Auditory Brainstem Response Findings

Karupaiah Kamalakannan*, Aronprabu Chrislin Sona, Sivagnanam Sivaranjani, Surendran Thiriveni, Kumaar Bhuvaneswari, Prashanth Prabhu

Auditory and Vestibular Research, Volume:32 Issue: 4, Autumn 2023, PP 344 -350

Background and Aim

The human blood group system can have an effect on the health and auditory system. The present study aimed to determine the differences in the Auditory Brainstem Response (ABR) recordings among persons with different blood groups (AB, A, B, O).

Methods

Sixty adults aged between 18 and 25 years with normal hearing sensitivity took part in the study. Further, they were grouped into four groups based on their blood groups (A, B, AB, O). Each group consisted of 15 participants. Auditory brainstem responses were recorded for all the participants at different rates (11.1/s and 90.1/s).

Results

The results of the study showed that the amplitude of ABR waves was significantly reduced for individuals with blood group O at lower repetition rate. The amplitude and latency of wave V was reduced at higher repetition rate among individuals with blood group O. There was no significant difference for all the other parameters across the groups.

Conclusion

The result of the study suggests the possibility of lesser auditory nerve functioning and increased risk of cochlear synaptopathy in persons with the O blood group.

Keywords: Auditory brainstem response, outer hair cell, auditory nerve, cochlear, synaptopathy}

Abstract View Paper Research/Original Article Original: English
Cochlear Dysfunction in Chronic Otitis Media and Its Determinants

Vijayalakshmi Subramaniam, Ali Ashkar, Sheetal Rai *

Iranian Journal of Otorhinolaryngology, Volume:32 Issue: 2, Mar-Apr 2020, PP 79 -84

Introduction
Long-standing chronic otitis media (COM) may lead to sensorineural hearing loss (SNHL). The present study aimed to evaluate the factors affecting the sensorineural component to counsel patients regarding the risk of SNHL at the event of untreated COM.
Material and Methods
A time-bound cross-sectional study was conducted in the Department of Otorhinolaryngology at a tertiary care hospital. The study population included the study group comprising 137 patients with chronic suppurative otitis media (CSOM) and the control group which consisted of 137 individuals with the same age range and gender as the case study group. Moreover, the hearing was assessed using a pure tone audiogram and specialtests of hearing.
Results
Based on the findings of the present study,the SNHL was found in 71.4% of CSOM cases with an ear discharge duration of more than 5 years. The SNHL occurred in 55.2% and 44.7% of the cases with pars flaccida and of pars tensa perforations, respectively. In the case of pars tensa perforation, greater perforation size resulted in a steady increase in the odds of developing SNHL. Patients with subtotal and total perforations were at higher risk of developing SNHL.
Conclusion
Patients with longer duration of disease, squamous type of disease, and larger size of pars tensa perforation had greater susceptibility to develop SNHL. Therefore, eradication ofthedisease from the middle ear and early reconstruction of the hearing mechanism duringthe course of the disease result in reducing the burden of SNHL.

Keywords: Cochlear, Chronic otitis media, Sensorineural hearing loss}

Abstract View Paper Research/Original Article Original: English
بررسی تاثیر استفاده از حجم (کانتور) گوش داخلی به جای کانتور حلزون گوش بر محاسبات دوز- حجم حلزون گوش در پرتودرمانی دو بعدی سنتی و سه بعدی تطبیقی تومورهای مغز

سمیه کریمی، علیرضا عموحیدری، ایرج عابدی، پروانه شکرانی

مجله دانشکده پزشکی اصفهان، پیاپی 476 (هفته چهارم خرداد 1397)، صص 398 -402

مقدمه
کم شنوایی حسی عصبی از عوارض رادیوتراپی در بیماران مبتلا به تومورهای مغزی می باشد.سیستم شنوایی بیماران مبتلا به تومورهای مغزی درون میدان تابشی قرار میگیرد ودوز قابل توجهی از پرتو را دریافت و ایجاد کاهش شنوایی می کند. هدف از این مطالعه مقایسه کانتورکردن ودز رسیده حلزون گوش و گوش داخلی در دو روش درمانی دوبعدی سنتی(2D) و سه بعدی تطبیقی (3D)در بیماران مبتلا به تومور های مغزی بود.
روش ها
تصاویرCT 43 بیمار(23 مرد20زن) مبتلا به تومورمغزی که در سال 1395مرکز پرتودرمانی بیمارستان میلاد اصفهان مراجعه کردند مورد استفاده قرارگرفت.کانتور کردن حلزون گوش و گوش داخلی روی سی تی اسکن بیمار توسط پزشک انکولوژیست درنرم افزار طراحی درمان TiGRT انجام گرفت.هیستوگرام های دز(DVH) درمان های پرتودرمانی 2D (دومیدان جانبی موازی ومخالف) و3D(دومیدان جانبی موازی و مخالف ویک فیلد ورتکس با وج وکولیماتورچند برگیMLC))( محاسبه ومورد مقایسه قرارگرفت.
نتایج
میانگین دز رسیده درروش3D برای حلزون گوش برابر 338.7± 2624 و برای گوش داخلی 341.3±2718 بود ودر روش پرتو درمانی3D برای حلزون گوش294.6 ±2507 ، برای گوش داخلی 295.6±2581 بود میانگین دزحلزون گوش و گوش داخلی در روش3D به ترتیب 5.3% و 4.6% کمتر از روش 2Dبود
بحث و
نتیجه گیری
بررسی پارامتر های دزیمتریک مربوط به سیستم شنوایی در طراحی درمان دو روش پرتودرمانی نشان داد که اختلاف معناداری بین دز رسیده به حلزون گوش وگوش داخلی در روش2D و 3D وجود نداشت ( P values= 0.86، 0.85). بنابراین در طراحی درمان این دو روش پرتو درمانی می توان کانتور کردن گوش داخلی را جایگزین کانتور حلزون گوش نمود.

کلید واژگان: کانتور کردن, حلزون گوش, گوش داخلی, DVH, پرتو درمانی دو بعدی سنتی و سه بعدی تطبیقی, تومور مغزی}

چکیده مشاهده متن مقاله پژوهشی/اصیل زبان: فارسی

Effect of replacing cochlea contour with inner ear contour on cochlea dose-volume calculations in conventional 2 dimensional and conformal 3 dimensional radiotherapy of brain

Somayeh Karimi, Alireza Amouheidari, Iraj Abedi, Parvaneh Shokrani

Journal Of Isfahan Medical School, Volume:36 Issue: 476, 2018, PP 398 -402

Introduction
Sensorineural hearing loss is a radiotherapy complication in patients with brain tumors.The auditory system of patients with brain tumors often is placed inside of radiation field and receives a significant amount of radiation dose resulting in hearing loss.The purpose of this study was to compare contouring and delivery dose to cochlea and inner ear in two techniques of 3D conformal radiotherapy vs 2D conventional radiotherapy in patients with brain tumors.
Methods and materials:Computerized tomography (CT) scan of43 patients(23male and20 female) were used.Patients were treated for brain tumor at the radiotherapy unit of Isfahan Milad Hospital 2016.Contouring of cochlea and inner ear were done on patients CT.by Radiation oncologist.using TiGRTtreatment planning system.Dose volume histograms (DVHs) for methods of 2D (two parallel and opposite fields) and 3D (two parallel and opposite field and a vertex field using wedge and Multileaf collimators(MLC)) were compared.
Results
The mean dose in 2D technique for the cochlea was 2624 ± 338.7and for the inner ear was 2718.3 ± 341.3,and in 3D radiotherapy technique for the cochlea 2507±294.6,and for inner ear was 2581± 295.6.The mean dose of inner ear and cochlea in 3D was 5.3% and 4.6%lower than 2D,respectively.
Conclusion
The study of dosimetric parameters of the auditory system in treatment planning of two methods of radiation therapy showed that there was no significant difference between the doses of cochlea and inner ear in 2D and 3D methods (Pvalues=0.86,0.85).Therefore in treatment planning of these two radiotherapy techniques, contour of cochlea can be replaced by inner ear.

Keywords: Contouring, Cochlear, Inner ear, DVH, 2D, 3D dimensional radiotherapy, Brain tumor}

Abstract View Paper Research/Original Article Original: Persian
Speech Intelligibility of Cochlear-Implanted and Normal-Hearing Children

Sara Poursoroush, Ali Ghorbani, Zahra Soleymani, Mohammad Kamali, Negin Yousefi, Zahra Poursoroush

Iranian Journal of Otorhinolaryngology, Volume:27 Issue: 5, Sep 2015, PP 361 -367

Introduction
Speech intelligibility, the ability to be understood verbally by listeners, is the gold standard for assessing the effectiveness of cochlear implantation. Thus, the goal of this study was to compare the speech intelligibility between normal-hearing and cochlear-implanted children using the Persian intelligibility test.
Materials And Methods
Twenty-six cochlear-implanted children aged 48–95 months, who had been exposed to 95–100 speech therapy sessions, were compared with 40 normal-hearing children aged 48–84 months. The average post-implanted time was 14.53 months. Speech intelligibility was assessed using the Persian sentence speech intelligibility test.
Results
The mean score of the speech intelligibility test among cochlear-implanted children was 63.71% (standard deviation [SD], 1.06) compared with 100% intelligible among all normal-hearing children (P<0.000). No effects of age or gender on speech intelligibility were observed in these two groups at this range of ages (P>0.05).
Conclusion
Speech intelligibility in the Persian language was poorer in cochlear-implanted children in comparison with normal-hearing children. The differences in speech intelligibility between cochlear-implanted and normal-hearing children can be shown through the Persian sentence speech intelligibility test.

Keywords: Children, Cochlear, Implants, Language, Speech}

Abstract View Paper Original: English

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