جستجوی مقالات مرتبط با کلیدواژه "depression" در نشریات گروه "پزشکی"

Anemia in pregnancy is associated with psychiatric symptoms and poor psychiatric symptoms, this study investigates the 6-month trends of anxiety and birth outcomes. Considering the controversies surrounding the impact of anemia on psychiatric symptoms, this study investigates the 6-month trends of anxiety and depression in anemic pregnant women with threatened abortion (TA).

A case-control retrospective cohort study conducted among 282 participants who enrolled in a registry of pregnant women with TA in Babol city from December 2022 to October 2023. Fifty individuals with anemia (hemoglobin < 11 g/dL) who were matched with 50 without anemia based on age, pregnancies, education, and gestational age, were included. The BSI-18 (Brief Symptom Inventory) was used to assess depression, anxiety, and psychological distress at the beginning, three and six-month follow-ups.

The prevalence of anemia among women diagnosed with TA was found to be 17.7%. At the beginning, compared to normal individuals, anemic women had higher rates of depression (32% vs. 14%), anxiety (34% vs. 22%), and psychological distress (66% vs. 48%). Moreover, at 3- and 6-month follow-ups, the frequency of psychiatric symptoms in anemic women was significantly higher. The Generalized Estimating Equations model showed that although both groups had a decreasing trend of frequency anemic women experience a slower rate of decrease in psychiatric symptoms compared to non-anemic women.

Anemia in women with TA is associated with high rates of depression, anxiety, and psychological distress, as well as a slow recovery rate.

The aim of this study is to investigate the possible role of the hippocampal BDNF-PI3K-AKT signaling pathway in the antidepressant-like activity of ellagic acid (EA) in mice.

Male BALB/C mice were divided into 5 groups; vehicle (0.1 ml/day), sertraline (5mg/kg), EA (1 mg/kg), EA+BKM120 (PI3K inhibitor), EA+MK2206 (AKT inhibitor). EA, sertraline and vehicle were injected intraperitoneally for 14 days. Locomotor activity was determined by open field test. The tail suspension test was used to detect the antidepressant-like effect. After behavioral tests, hippocampal tissue was obtained and Western blot analyzes were performed for BDNF and pAKT1. 

Sertraline and EA provided a reduction in immobility time in the tail suspension test when compared with the control group. BKM120 and MK2206 administration reversed this effect of EA. No statistical difference was found between groups in terms of locomotor activity. EA treatment caused an increase in hippocampal BDNF and pAKT1 levels in mice. While inhibitory agent administrations did not affect the increase of BDNF induced by EA, MK2206 administration reversed the increase in pAKT1 observed with EA.

It has shown that EA has an antidepressant-like effect in mice without changing locomotor activity, and this effect may be mediated by the BDNF-PI3K-AKT signaling pathway.

One of today's social problems is behavioral abnormalities and aggression and ways to deal with it. The purpose of this research was to examine the effect of neuro-linguistic programming (NLP) and cognitive behavioral therapy on the attention and aggression of high school students in Kerman.

With a control group, this semi-experimental study administered tests before and after the intervention. All 45 male and female students enrolled at Kerman's second-year secondary school were included in the statistical population. Fifteen of them were allocated at random to one of three groups: control, experimental group 1, or group 2. The first group had 18 45-minute NLP sessions, whereas the second group received 6 60-minute CBT sessions. None of the interventions were given to the control group. The data was collected using the DASS-21 scale.

Compared to the control group, the educational groups that focused on cognitivebehavioral approaches and natural language processing had lower average indices of mental health evaluation. Students' anxiety and stress levels were significantly reduced after receiving instruction in both techniques, according to multivariate variance analysis. Comparing the three groups' matched results from the follow-up test, there was no difference in statistical significance in anxiety reduction between the two methods; however, there was a significant difference in lowering stress and depression, with the NLP method showing greater efficacy.

cognitive-behavioral training is an effective method in increasing the mental health of students and this intervention can be used to improve academic performance in clinics and school health.

The goal of this study was to examine how self-criticism and cognitive flexibility relate to depression, taking into account the moderating effect of emotion control in depressed undergraduate females.

The present study's statistical population consisted of all female students at Isfahan Azad University in 1402 who exhibited signs of depression. 384 people were chosen using cluster random selection from the study's target population as a sample, using Cochran's formula. The research variables were measured using the Beck Depression Inventory, the Gross & John Emotion Regulation Questionnaire, the Gilbert et al. Self-Criticism Scale, the Dennis & Vander Wal Cognitive Flexibility Inventory, and the questionnaire on demographic characteristics. The acquired data were examined using the regression analysis technique and the statistical program SPSS version 27.

Findings showed that there is a significant relationship between cognitive flexibility and self-criticism with depression, cognitive flexibility and self-criticism with emotion regulation, and also between emotion regulation and depression (p<0.01). Also, the findings indicated that emotion regulation has a moderating role in the relationship between cognitive flexibility and self-criticism with depression (p<0.01).

Based on the findings of this research, it can be concluded that the relationship between cognitive flexibility and self-criticism with depression is not a simple linear relationship and emotion regulation can affect this relationship.

Depression is a prevalent mental health disorder with adverse effects on both physical and psychological health. Taekwondo is posited to exert a positive influence on depression, yet its efficacy warrants further verification.

This study employed meta-analysis to quantify the intervention effect of Taekwondo on depression. Concurrently, based on subgroup analysis results, an optimal intervention program was suggested. Multiple databases were searched, including English (Web of Science, PubMed), Chinese (CNKI, WANFANG DATA), and Korean (RISS, KISS, DBPIA), to retrieve randomized controlled trials (RCTs) studying Taekwondo's impact on depression, published up to Jan 2024. The Cochrane bias risk tool version 2 (RoB 2.0) was utilized for literature bias risk assessment. Comprehensive Meta-Analysis software facilitated the meta-analysis, subgroup analysis, and publication bias evaluation.

Fifteen articles, encompassing 1945 participants, were included in the study. The primary findings indicated a significant reduction in depression risk due to Taekwondo intervention (Effect Size [ES]=-0.635, P<0.001). Subgroup analysis revealed the most substantial intervention effects in elderly individuals (ES=-1.025, P=0.004) and women (ES=-1.114, P=0.009). Taekwondo exercises, when conducted over 12 wk (ES=-0.922, P<0.001), three times per week (ES=-0.729, P<0.001), for 60 min per session (ES=-0.980, P=0.003), and at low intensity (ES= -1.777, P=0.024), yielded the greatest depression mitigation effects.

Taekwondo is an effective means to alleviate depression, particularly in older women. The study recommends a low-intensity Taekwondo exercise regimen, consisting of 60-minute sessions, three times weekly for 12 wk, as an optimal exercise prescription for best outcomes.

Few studies have compared the concentration of trace elements and antioxidants in the serum of depressed and non-depressed as well as children on dialysis with and without anxiety.

 A prospective cross-sectional research was conducted. Forty children undergoing dialysis were assessed to define the correlation between mean serum levels of Selenium, Zinc, Copper, Manganese, vitamin C, and vitamin E and their deficient levels with mood disorders. The Child Depression Inventory (CDI) and Depression Anxiety Stress Scale (DASS) scorings were applied. According to Scorings, patients were divided into no depression and depression and no anxiety and anxiety disorders groups.

Eighteen hemodialysis and 22 peritoneal dialysis patients were enrolled. The median of age was 11 years. Twenty-two patients (55%) were males. Selenium, copper, and vitamin C deficiencies were found in 32.5%, 15%, and 2.5% of patients, respectively. Anxiety and depression disorders were diagnosed in 82.5% and 67.5% of patients, respectively. No relationship between gender, modality of dialysis, duration from onset of dialysis, serum levels of hemoglobin, blood urea nitrogen, albumin, Zinc, Copper, Selenium, manganese, and vitamin C with anxiety and depression disorders (p > 0.05 for all). The severity of depression was higher in hemodialysis versus peritoneal dialysis patients (P < 0.001). The Serum level of Vitamin E significantly was higher in depressed in comparison with non-depressed cases (P=0.02).

There was no relationship between trace elements and vitamin C serum level and depression or anxiety disorders. An unreported finding was significantly higher level of vitamin E in depressed patients in comparison to those without it.

The demand for orthodontic treatment to correct malocclusion has increased worldwide. A main cause of applying for orthodontics treatment may arise from mental disorders, such as Body Dysmorphic Disorder (BDD). This study aimed to investigate the relationship between BDD, the real need for orthodontic treatment based on the ICON index, and inquiry about orthodontics treatment in women. 

In a case-control study, 414 women from the public outpatient dental clinic of Mashhad University of Medical Sciences, completed a demographic questionnaire, Beck Depression Inventory (BDI II), Beck Anxiety Inventory (BAI), and Yale-Brown Obsessive-Compulsive Scale Modified for BDD (BDD-YBOCS). A specialist also determined the ICON index for each participant. 

Among 414 subjects, 52 patients (31 in the orthodontics and 21 in the control group) (p=0.182) had a BDD-YBOCS score of 20 or above. The frequency of BDD, based on a definite diagnosis by an interview with a psychiatric specialist, was 6.28% among the orthodontic patients, which was significantly more than that of other dental patients (p<0.05). The mean ICON index score was found to have a significant difference between the orthodontic patients and the controls (p<0.001). No correlation was found between the severity of ICON and BDD-YBOCS scores in all the participants (p=0.804), in the cases (p=0.655), or the controls (p=0.403). 

The current study found no correlation between ICON and BDD score. However, a significantly higher rate of BDD subjects receiving orthodontic procedures suggests using the BDD-YBOCS survey in dental clinics to screen patients suspected of having BDD for further psychological management.

Nurses are exposed to higher stress, anxiety, and depression due to the nature of their work. Considering the differences between specialized and general hospital units, this article focuses on comparing the levels of stress, anxiety, and depression among nurses in these two types of units.

This descriptive‑analytical study was conducted in 2023 on 135 nurses in specialized units and 219 nurses in general units selected through stratified random sampling out of 1681 nurses. For this study, 6 public hospitals in the West Azerbaijan province of Iran were selected. Data were collected through a demographic questionnaire and the Depression, Anxiety, Stress Scales‑21 (DASS‑21) and analyzed using SPSS software. A significance level of 0.05 was considered for this study.

This study reported that stress, anxiety, and depression affected 72.04%, 46.33%, and 53.68% of nurses, respectively, with mild to extremely-severe intensity levels. No significant differences were observed in stress, anxiety, and depression between specialized and general units (p > 0.05). Among specialized units (ICU, CCU, and dialysis ward), dialysis unit nurses had significantly lower depression scores (p < 0.05). Additionally, a significant correlation existed between demographic variables and DASS‑21 constructs (p > 0.05).

The similarities among nurses in specialized and general units outweigh the observed differences. Given the high prevalence of stress, anxiety, and depression among nurses and the negative correlation with job satisfaction, managers should improve job satisfaction to support nurses’ mental health.

Any deviation from the normal trajectory of gender identity formation creates a basis for incompatibilities, a specific and severe form of which is gender identity disorder (GID). Gender identity disorder affects an individual’s development, growth, and overall performance.

This study aimed to investigate the prevalence of depression, anxiety, and aggression among individuals with GID, based on their personality type (type A or type B), referred to the Forensic Medicine Department of Ilam city in 2020.

In this cross-sectional study, all patients diagnosed with GID and referred to the Forensic Medicine Department for gender reassignment were included. All participants received psychological counseling from a psychiatrist. To determine levels of depression, anxiety, personality type, and aggression, Beck’s Depression and Anxiety Inventory, the Aggression Questionnaire (AGQ), and Spencer’s Type A or B Personality Type Questionnaire were used, respectively. Data were analyzed using t -tests, Fisher’s exact test, and linear regression through STATA 12 software.

The findings revealed that the mean ± SD total scores for depression and anxiety were 15.2 ± 9.2 and 21.4 ± 13.2, respectively. Among the patients, 21 (52%) exhibited no or very low depressive symptoms, three (8%) had mild symptoms, 12 (30%) had moderate symptoms, and four (10%) had severe depressive symptoms. Regarding anxiety, seven (17.5%) had no or very low symptoms, seven (17.5%) had mild symptoms, 12 (30%) had moderate symptoms, and 14 (35%) had severe symptoms. Among patients with personality types B and A, 11 (64.1%) and 10 (45.5%) individuals, respectively, had no depressive symptoms, while six (33.3%) and one (4.6%), respectively, exhibited no anxiety symptoms. The linear regression model indicated that aggression levels in type A personalities were approximately 6.23 points higher than those in type B personalities (P = 0.03).

Individuals with GID who have a type A personality are more susceptible to mental health disorders compared to those with a type B personality. Additionally, aggression levels in individuals with GID can be partially predicted based on personality type.

Cerebral palsy (CP) describes a group of permanent movement and posture disorders resulting from injury to the developing brain, affecting muscle movement and coordination. It causes lifelong physical and cognitive impairments.

This study examined the effects of a group psychoeducational intervention on anxiety, depression, and quality of life in mothers of children with CP.

This quasi-experimental study involved 50 mothers (25 in the intervention group and 25 in the control group) of children with CP aged 2 - 11 years. Mothers in both groups completed the Beck Depression Inventory, Beck Anxiety Inventory, and Short Form-36 health survey before and after the interventions. The intervention group received a 5-session (1 hour per session), weekly psychoeducational program that provided information about CP, stress management techniques, problem-solving skills, and social support. The control group received no intervention during this period. Follow-up assessments were conducted at 2 months post-intervention to evaluate outcomes.

Psychoeducation significantly reduced anxiety and depression and improved quality of life compared to the control group (P < 0.001). Also, group × time interactions were significant for all dependent variables (P < 0.001).

A brief group psychoeducational intervention effectively decreased anxiety and depression and enhanced the quality of life in mothers of children with cerebral palsy.

Hypertension is the most significant modifiable risk factor for cardiovascular disease (CVD) and is associated with substantial negative effects on both individual and societal levels. Renal denervation (RDN) has been established as a safe and effective medical intervention for treating resistant hypertension, with approval from the Food and Drug Administration and endorsement by guidelines such as those of the European Society of Cardiology (2023) and the American Heart Association. However, with the advent of various types of RDN methods, including radiofrequency-, ultrasound-, and alcohol-based techniques, debates have intensified regarding their comparative efficacy and safety. Additionally, researchers have expanded their focus to consider outcomes beyond hypertension management. Most studies have demonstrated that this non-pharmacologic treatment significantly improves systolic and diastolic 24-hour ambulatory and office blood pressure in both the short- and long-term. Despite these findings, the social and psychological impacts of RDN on a broader scale have been less frequently discussed. Given the high burden of hypertension and its complications, such as cardiovascular and cerebrovascular events, this intervention could substantially enhance the quality of life and mental health of affected populations. Non-adherence to antihypertensive medications remains a critical challenge, driven by factors such as side effects, pregnancy, financial constraints, psychiatric disorders, and polypharmacy with its associated consequences. Renal denervation, by improving blood pressure control, offers the potential to enhance quality of life and reduce the incidence of severe physical and mental health conditions. This study provides a comprehensive perspective on this advanced treatment, emphasizing its impact on individual and societal well-being, physical health, and mental health.

With the increasing prevalence of infertility and its links to depression, anxiety, and stress, it is essential to compare these mental health levels between infertile men and a control group.

This study aimed to compare depression, anxiety, and stress among infertile and fertile men. Also, assessing demographic factors affecting these challenges among both groups.

This case-control study was conducted on 120 men at Milad Infertility Research Center, Mashhad, Iran from January 2023 to February 2023. Participants were divided into 2 groups: 60 infertile men and 60 healthy men who did not have fertility problems. Demographic information such as age, education, occupation, duration of the marriage, and duration of infertility was collected from their medical records, and they also completed the depression, anxiety, and stress scale 21 questionnaire through a telephonic interview. Finally, the findings were statistically analyzed.

Severe and very severe depression, anxiety, and stress were observed in 65%, 60%, and 43.4% of infertile men and 16.7%, 23.3%, and 11.7% of fertile men, respectively. Which was significantly more than the fertile group, and there was a significant relationship between depression (p ≤ 0.001), anxiety (p = 0.001), stress (p ≤ 0.001), and infertility. Also, a significant relationship was observed between the duration of infertility and depression (p = 0.031).

Our study found infertile men had higher stress, anxiety, and depression than the control group. Limitations included phone-based data collection and the depression, anxiety, and stress scale 21 questionnaire's screening nature. Future studies should involve larger populations and consider economic status as a variable related to mental health.

Students making the transition from high school to university find it difficult to maintain good eating routines/lifestyles and mental health, due to time constraints and stress. The goal of the study was to analyse the correlation between previously mentioned topics.

We included 948 students, aged 18-27, at the Faculty of Medical Sciences in Serbia and the research was conducted in 2020. Chi-square was used for statistical analysis. Modified WHO questionnaire for lifestyle and eating habits was used, as well as standardized questionnaires for anxiety and depression.

Respondents who had more prominent symptoms of depression (moderate or severe) and anxiety had a significantly higher percentage of eating less than three meals a day (47.7%, 35.7%), skipped breakfast (38.6%, 33.5%), consumed alcohol (11.4%, 3.8%), used energy drinks (38.6%, 31.7%), were on some type of diet (36.6%, 30.2%), were not satisfied with their appearance (66.7%, 53%) and not engaging in physical activity (43.2%, 33.1%). Significant predictors for severe depressive and anxiety symptoms were the consumption of alcoholic beverages, energy drinks, satisfaction with personal appearance and physical activity during a day.

The results suggest that some of the eating and lifestyle habits were linked to higher risks of developing depressive or anxiety symptoms.

Lifestyle and social health in fertility play a decisive role on mental health, and infertility is one of the unpleasant life experiences that can affect a person's mental health. In addition, marital satisfaction is also affected by infertility and plays an important role in the mental health of couples.

In order to find the relationship between these factors mentioned in the "background" section, this study aimed to determine a predictive model of depression in infertile women based on lifestyle and social health components mediated by marital satisfaction.

The present study was a descriptive and correlational study in which 360 infertile women were selected based on the depression score obtained from the Beck questionnaire (score 8 and above). Then, social health, lifestyle, and marital satisfaction questionnaires were completed by the selected infertile women. Subsequently, the raw data obtained were analyzed using SPSS-Ver.22 and partial least squares (PLS)-Version 3 software. Finally, a predictive model was designed based on the relationship and correlation between the variables.

The findings showed that there is a significant relationship between social health and depression (r = -0.55, P < 0.01), between social health and marital satisfaction (r = 0.48, P < 0.01), between social health and lifestyle (r = 0.52, P < 0.01), lifestyle and depression (r = -0.41, P < 0.01), between lifestyle and marital satisfaction (r = 0.59, P < 0.01), and between marital satisfaction and depression (r = -0.61, P < 0.01). Negative values of the above-mentioned correlations (r) indicate an indirect relationship and positive “r” values indicate a direct correlation.

Based on the results of the present research, the main hypothesis of this research was confirmed and it can be concluded that the model designed to predict the depression of infertile women based on lifestyle and social health components with the mediation of marital satisfaction is valid.

Migration is a widespread phenomenon globally, often leading to adverse mental health impacts for migrants, particularly children. Such impacts highlight the importance of appropriate non-pharmacological interventions to mitigate these potential negative outcomes. Depression is one of the most prevalent psychological consequences among immigrant children and, therefore, requires focused intervention and treatment.

This study aimed to evaluate the effectiveness of the modified complicated grief therapy (MCGT) intervention in reducing symptoms of depression in immigrant children.

For this study, 20 Canadian immigrant children were selected using simple random sampling, with ten assigned to the intervention group and 10 to the control group. Depression levels in participants were measured using the Children's Depression Inventory (CDI) self-report questionnaire, which has demonstrated validity and reliability in previous studies. The intervention method, MCGT, was delivered to the intervention group across 12 online sessions via Google Meet, while the control group received no intervention. Depression levels were assessed at three points: Pre-intervention, immediate post-intervention, and one-month post-intervention. Data were analyzed using SPSS version 22, applying relevant statistical tests to compare pre-and post-intervention scores across study groups.

The results indicated that of the 20 children selected, 9 (45%) were boys and 11 (55%) were girls, with an average age of 11.7 ± 1.79 years. The mean ages of fathers and mothers were 41.35 ± 4.96 and 37.35 ± 5.04 years, respectively. Findings showed no statistically significant difference in the average depression scores between the control and intervention groups before the intervention (P = 0.561). However, a statistically significant difference was observed in the mean depression scores between the control and intervention groups immediately after the intervention (P = 0.003) and one-month post-intervention (P < 0.001). In the intervention group, the average depression score decreased by 6.5 points immediately after the intervention and by 10.6 points one month later, whereas an increasing trend in depression scores was noted in the control group.

Based on the results, the MCGT intervention method is effective and significant in reducing the depression level of immigrant children. Therefore, counselors and psychologists are suggested to use the MCGT intervention method (as a non-drug method) to reduce depression in children.