جستجوی مقالات مرتبط با کلیدواژه "diagnostic delay" در نشریات گروه "پزشکی"

The aim of this study was to determine the endometriosis-associated symptoms and diagnostic delay through an online survey.

A cross-sectional study was conducted in Australia using an online web-based survey. All data were entered into and analyzed using the STATA software (version 14.1). A total of 903 respondents completed an online survey from September 2013 to October 2015.

Out of 903, 71.10% were Australians and 28.90% were Non-Australian, with a self-reported diagnosis of endometriosis confirmed by surgery. Out of the participants, 86.5% completed the online survey. Delay in diagnosis was 8.1±6.2 years. There was no difference in the age range (P = 0.35), mean age of onset of the first symptoms (P = 0.93), and delay in diagnosis (P = 0.11) between both groups. Most common endometriosis-related symptoms that all respondents had experienced in their lifetime were period pain (98.1%), fatigue (94%), bloating (90.7%), ovulation pain (88.7%), pelvic pain (87.3%), pain during and before/after sexual activity (82.7%), and heavy bleeding (82.2%). Treatments used by affected women included: pain killers (96%), hormonal medication (84.7%), surgical treatments (84.5%), and delayed fertility (37.1%).

Vast similarities in demographics and endometriosis-associated symptoms among the Australian and non-Australian women with endometriosis support the universality of the disease characteristics. Delay in diagnosis of endometriosis is a problem and the reasons for delayed diagnosis must be understood to try to shorten this delay. Besides pain, patients with endometriosis suffer from a variety of other symptoms; hence, any treatment must take into account the most prominent symptoms.

Chronic Granulomatous Disease (CGD) can be associated with several neurological complications. Abscess in the brain in patients diagnosed with CGD has been reported in several publications. Different pathogens have been linked with brain abscess development including fungal or bacterial infections. Other neurologic complications may include white matter disease and formation of a granulomatous lesion in the central nervous system. In addition to these common reports, observation of leptomeningeal, along with focal brain infiltration by pigmented, lipid-laden macrophages, fungal brain infection, Aspergillus abscess resembling a brain tumor, spinal cord infection by Aspergillus, and fungal granuloma of the brain have also been described. Physicians should be aware of Streptococcus- and Candida-induced meningitis in a selected group of CGD patients as well. Herein, we report a case of the attenuated ill-defined lesion in the right cerebellar hemisphere in a CGD patient without involvement of the sinuses or lungs.

Enteropathy is one of the rare manifestations of common variable immunodeficiency (CVID) as a predominant antibody deficiency. Proper diagnosis of this phenotype in CVID cases is difficult and may result in inaccurate assessment or incorrect management.Further, this misdiagnosis is more probable when noninfectious diarrhea is the only manifestation of CVID. We present herein a case with such an abstruse condition who was misdiagnosed as a celiac disease leading to delayed diagnosis of her primary immunodeficiency disease. We also offer a review on enteropathy manifestation in CVID patients.

Despite recent advances in treatment of oral cancer, it still causes high rates of mortality and morbidity worldwide. Delays in diagnosis and treatment of these cancers greatly affect the prognosis. This study aimed to assess the treatment delay and its relation to diagnostic delay among oral cancer patients in Tehran, Iran. We studied 100 patients with primary oral squamous cell carcinoma who were admitted to three teaching hospitals between 2004 and 2006. Treatment delay was defined as the time from diagnosis to the beginning of treatment. Diagnostic delay is considered as the time elapsed between the onset of symptoms and diagnosis. Of all the patients 53% were male with the mean age of 61.5 (SD 15.8 years; range 24-100 years) at diagnosis. The majority of tumors (61%) were at advanced stages when diagnosed (stages III or IV). The mean diagnostic delay was 7.2 months (SD 7.5) and the mean treatment delay was 33.16 days (SD 14.1). Patients who were diagnosed at earlier stages had longer treatment delays (p<0.05), and those who had longer diagnostic delay had shorter treatment delay (p<0.05). Our findings indicated a need for oral cancer prevention campaigns, focused on reducing the delays between the appearance of signs and symptoms, and final diagnosis and treatment to ensure better prognosis and higher quality of life for patients.