جستجوی مقالات مرتبط با کلیدواژه « endometrial ablation » در نشریات گروه « پزشکی »

The purpose of the study was to evaluate the effectiveness and safety of thermal balloon ablation in women with high anesthetic and surgical risk compared to invulnerable women according to the American Society of Anesthesia (ASA) physical status stratification.

This report was based on a retrospective cohort study of women with heavy menstrual bleeding (HMB) who were eligible for treatment with CavatermTM plus during 2012-2017. Women were classified as high-risk (HR) or low-risk (LR) cohorts based on ASA physical status stratification. The primary outcome includes amenorrhea in the twelfth months after the treatment. Risk adjustments were performed using regression models.

This research study consisted of 63 women with mean age 44.42±5.48. Mean of body mass index (BMI) in the HR cohort was higher than the LR cohort (31.48±6.22 vs 26.83± 3.51, P=0.005) and results were also similar considering the uterine length (mm) between HR and LR women (58.27±35.70 vs 30.92± 35.30, P=0.01). The primary outcome of treatment after a one-year follow-up in the two groups (HR and LR) was 31 (93.9%) and 15 (78.9%), respectively. After adjusting for known confounders including age, uterine length, parity, dysmenorrheal, the adjusted odds ratio was 0.94 (95% CI, 0.14– 2.5; P= 0.60).

For women with high anesthetic and surgical risks derived from serious underlying co morbidities, endometrial ablation can provide a minimally invasive, safe, and effective therapy for heavy menstrual bleeding.

Dysfunctional uterine bleeding (DUB) is the most common gynecologic disorder in women of reproductive age. Medical treatments are often ineffective. Endometrial ablation is an alternative to hysterectomy for these women.. To evaluate the response to treatment rate of the Cavaterm TM plus technique for management of menorrhagia secondary to dysfunctional uterine bleeding (DUB)..Patients and In this clinical trial study 40 women aged 35-50 years with menorrhagia secondary to DUB, who had been referred to the gynecology clinic of Arash Hospital, Tehran, Iran, were recruited. They underwent endometrial ablation via Cavaterm™ plus system and were followed for one year.. The observed mean number of days of bleeding per month decreased significantly from 14.95 ± 6.7 days before treatment to 3.42 ± 3.04 days after treatment (P < 0.001). Intervals between hemorrhagia increased significantly from 16.25 ± 5.50 to 21.30 ± 11.10 days (P = 0.01). The rate of dysmenorrhea decreased significantly from 32.5% to 10% (P < 0.05). The improvement rate of dysmenorrhea was 69.5%. The overall improvement of menorrhagia was reported 92.5% (P < 0.001). After one year the rates of hypomenorrhea, amenorrhea and eumenorrhea were 47.5%, 27.5% and 17.5%, respectively..The failure to treatment rate was reported 7.5%. Patient satisfaction rate was 85%.. The Cavaterm™ plus system is a safe and effective technique and it can be an excellent alternative to hysterectomy for the treatment of menorrhagia due to DUB..

In order to assess the efficacy of hysteroscopic endometrial ablation and factors which are important in it's success, a prospective, randomized study was performed in Shiraz university hospitals between Sep. 1995 to Feb. 1998. 50 patients with chief complaints of menorrhagia that were in reproductive age (25- 50 years) and had shown no response to medication and D;C underwent endometrial ablation. Thirty-seven patients received pre-op medication and thirteen patients did not. All patients had undergone pre-operative endometrial sampling that had demonstrated benign histology. Eleven patients had submucosal myomas or pedunculated polyps that were resected at the time of hysteroscopic ablation. The minimum follow-up period was 1 year. Amenorrhea developed in 14% of patients, 50% of patients became hypomenorrheic and 30% eumenorrheic. Menorrhagia did not respond in 3 patients (6%). Hypermenorrhea was detected more commonly in younger patients. Type of endometrium, depth of the uterine cavity, presence of polyp or myoma and receiving pre-op medication were not important and did not affect patient response. Overall, the results of this study clearly indicate that endometrial ablation is a simple, effective and acceptable procedure for the management of intractable menorrhagia. The only factor which was important concerning the efficacy of endometrial ablation was patient age.