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جستجوی مقالات مرتبط با کلیدواژه « febrile convulsion » در نشریات گروه « پزشکی »

  • Noormohammad Noori, Alireza Teimouri *, Ali Khajeh, Elham Shafighi Shahri
    Background

    Epilepsy, febrile convulsion, and breath-holding spells are neurological diseases affecting the heart.

    Objectives

    This study aimed to evaluate electrocardiography alterations in children with epilepsy, febrile convulsion, and breath-holding spells compared to controls.

    Methods

    This case-control study was conducted on 360 children aged 0.5 - 5 years in Zahedan, Iran. The children with epilepsy, febrile convulsion, and breath-holding spells were diagnosed by a single neurologist based on the standard definition. Electrocardiography was also performed by a pediatric cardiologist. The data were analyzed using the SPSS 20.0 software, and P < 0.05 was considered statistically significant.

    Results

    Among the participants, 160 (44.4%) were female. Females also comprised 45.6%, 42.2%, 38.9%, and 51.1% of the participants in the epilepsy, febrile convulsion, breath-holding spells, and control groups, respectively. QTd was different in the epilepsy group compared to the controls and patients with breath-holding spells (P < 0.001). Additionally, QTc was significantly different in the epilepsy group in comparison to the controls (P < 0.001) and patients with breath-holding spells (P = 0.020), in the controls compared to the patients with febrile convulsion (P < 0.001), and in the controls in comparison to the patients with breath-holding spells (P < 0.001). QTcd was also different in the epilepsy group compared to the controls (P < 0.001), patients with breath-holding spells (P < 0.001), and those with febrile convulsion (P = 0.006) as well as in the controls in comparison with the patients with febrile convulsion and breath-holding spells (P < 0.001). Finally, QT was different in the patients with breath-holding spells compared to those with epilepsy (P = 0.005), in the patients with breath-holding spells in comparison with the controls (P = 0.002), and in the patients with breath-holding spells compared to those with febrile convulsion (P < 0.001).

    Conclusions

    The present study findings indicated that QT dispersion was different in the epilepsy group compared to the patients with breath-holding spells, corrected QT was different in the epilepsy group compared with the patients with breath-holding spells, QTc dispersion was different in the epilepsy group in comparison with the patients with breath-holding spells and febrile convulsion, and QT was different in the patients with breath-holding spells compared to those with epilepsy and febrile convulsion.

    Keywords: Electrocardiography, Epilepsy, Febrile Convulsion, Children}
  • MohammadSaeed Sasan *, Saeid Ameljamehdar, Nahid Donyadideh
    Background

    More than 20 years after the introduction of the mumps vaccine in the Iranian national vaccination program, there are concerns about meningitis induced by the Measles, Mumps, and Rubella (MMR) vaccine. The aim of this study is to virologically determine the incidence of MMR-induced meningitis in Mashhad, Iran.

    Method

    This is an observational prospective study during which all children who were admitted (in all hospitals of Mashhad) under the clinical suspicion of meningitis and had a history of MMR vaccination during the past 45 days were included. A polymerase chain reaction (PCR) test for mumps virus and enterovirus (EV) was done on cerebrospinal fluid (CSF) samples with pleocytosis.

    Results

    During 13 months of study, 55 children were hospitalized for suspicion of meningitis and had a history of recent MMR shots (94% presented with a febrile seizure). Meningitis was confirmed by CSF pleocytosis in 23 (2 bacterial and 21 aseptic) cases (44.2%). All incidents of meningitis had occurred after the first MMR. The incidence of any kind of aseptic meningitis, EV meningitis, and mumps meningitis during 45 days after the first MMR was, respectively, 19.9, 5.71, and 1.9 per 100,000 cases. The number of meningitis cases during the first 3 months after MMR was, respectively, 4.5 and 2 times more than the cases that occurred during the 3 months before and 3-6 months after MMR.

    Conclusion

    Around 40% of all cases of meningitis (between 4 and 43 months of age) occur during the first 3 months after the first MMR vaccination (12-15 months). The disproportionate increase of aseptic meningitis after the first MMR is strong epidemiologic evidence in favor of mumps vaccine induced meningitis.

    Keywords: Mumps, Meningitis, Febrile convulsion, Vaccine, Iran}
  • Elhan Bakhtiari, Farhad Heydarian *, MohammadAli Kiani, Zahra Askari, Mohammad Heidarian
    Objective

    The aim of present study was evaluation and comparison of the white blood cell, erythrocyte sedimentation rate (ESR) and C reactive protein (CRP) in febrile children with or without convulsion.

    Methods

    Three hundred sixty eight febrile children aged 6-60 months with or without convulsion were studied. Demographic, white blood cell (WBC), ESR and CRP were compared and analyzed.

    Results

    There was 368 children (184 patients with febrile convulsion as case group and 184 febrile patients without convulsion as control group), with the average age of 26.6±14.4 months and 17.71±15.4 months respectively (p=0.001). In case group 59.78% and in control group 43.48% were male (p=0.002). There was no significant difference between groups regarding WBC, ESR and CRP. There was significant relationship between leukocytosis and convulsion in patients with longer than 15 minutes convulsion (p=0.03). There was not any significant relationship between febrile convulsion patients according to type, duration and frequency of convulsion in ESR and CRP.

    Conclusion

    Leukocytosis and elevated ESR and CRP in patients with febrile convulsion can represent underlying etiology of the fever and it may not be due to convulsion itself. But in longer than 15 minutes convulsion, it can lead to leukocytosis itself.

    Keywords: Febrile convulsion, Child, white blood cell}
  • Farhad Heydarian *, Neda Fakhr Ghasemi, Elham Bakhtiari, Hasan Golmakani, Mohammad Heidarian
    Introduction

    Febrile seizure (FS) is a highly frequent presenting complaint in children. It is defined as a seizure that occurs in children between 6 to 60 months related to a fever of 38°C or more without any other explanatory causes of seizure such as evidence of central nervous system (CNS) infection or a previous seizure without fever. The aim od study is to evaluate mean folic acid serum levels in febrile children with or without seizures.

    Methods

    The mean folic acid serum levels and demographic data of 100 children aged 6 to 60 months, admitted to the Ghaem Hospital of Mashhad, Iran in 2018-2019, were collected, where the patients with febrile seizure were considered as the case group and the febrile ones without seizure as the control group. The inclusion criteria were children aged 6 to 60 months with febrile seizures who were admitted to the pediatric ward. The exclusion criteria were having a past medical history of seizure, meningitis, or encephalitis.

    Results

    There were 49 febrile convulsive children (cases) and 51 febrile children without a seizure (controls). The mean serum folic acid level was 7.07 and 9.89 ng/ml for cases and controls respectively (P-value < 0.001).

    Conclusion

    Children with febrile seizures had significantly lower serum folic acid levels than febrile children without a seizure.

    Keywords: Febrile convulsion, Fever, folic acid, Seizure}
  • Mitra Naseri*, Eltham Bakhtiari, Niayesh Tafazoli
    Introduction

    Febrile convulsion (FC) is the most common seizure disorder in childhood. Few studies focused on epidemiologic characteristics of urinary tract infections accompanied by FC.

    Objectives

    To evaluate prevalence and incidence rates of FC among children with urinary tract infection. Patients and

    Methods

    An observational study in epidemiology was performed in nephrology clinic of a tertiary children hospital from June 2002 to 2016. Totally 1242 cases were followed and those aged 6-60 months enrolled in the study. Demographic characteristics were compared between patients with and without FC.

    Results

    784 cases including 704 girls (89.8%) and 80 boys (10.2%) enrolled. Twenty-five patients (3.18%) presented with FC. FC occurred in 25 of 503 cases (5%) with febrile urinary tract infection. Twenty girls and 5 boys were in FC and 684 girls and 75 boys were in non-FC groups (P= 0.1). The average age in FC and non-FC groups were 15.52±8.4 and 25.16± 16 months respectively (P=0.004). Patients were divided into 2 age sub-groups: 6-24 and 26-60 months. A significantly higher number of cases in FC compared with non-FC group were in age subgroup of 6-24 months (P=0.028).

    Conclusion

    Our study revealed a prevalence rate of 3.18% and an incidence rate of 5% for FC among children with urinary tract infection. Also FC subjects had a significantly younger age at presentation than non-FC cases. We found that FC as presentation of urinary tract infection occurred up to 3 years old, and there is no significant gender difference between FC and non-FC cases.

    Keywords: Urinary tract infection, Febrile convulsion, Age, Gender}
  • حمید طالبیان پور، الهام طالبیان پور، حمید نعمتی، خسرو کشاورز*
    مقدمه

    عدم توجه به درمان بیماری تب و تشنج در کودکان، آنان را درگیر مشکلات جسمی، روانی و اجتماعی خواهد کرد و در صورت عدم درمان به موقع، زمینه ساز ابتلاء به صرع شده و کیفیت زندگی کودکان را تحت تاثیر قرار می دهد. مطالعه حاضر با هدف بررسی مقایسه تاثیر درمانی دو داروی فنوباربیتال و توپیرامات بر کیفیت زندگی کودکان زیر پنج سال مبتلا به تب و تشنج انجام شد.

    روش بررسی

    مطالعه حاضر از نوع توصیفی-تحلیلی بود که به صورت مداخله ای انجام شد. در این پژوهش، کیفیت زندگی 40 کودکی که دچار تب و تشنج بودند و تحت درمان با داروی توپیرامات بودند با 51 کودک دیگر که دچار همین بیماری بودند و داروی فنوباربیتال مصرف می کردند، مقایسه شد. ابزار گردآوری داده ها، پرسشنامه EQ5D بود. از آزمون های آماری ANOVA و t-test استفاده شد. داده ها در نرم افزار آماری SPSS نسخه 22 وارد شدند.

    یافته ها

     میانگین امتیاز کیفیت زندگی در کودکانی که فنوباربیتال و توپیرامات مصرف می کردند به ترتیب 72/5 و 82/7 بود. داروی توپیرامات تاثیر معناداری بر میانگین کیفیت کودکان مبتلا به تب و تشنج داشت و موجب افزایش آن شد. تحصیلات والدین و تب و تشنج اولیه با کیفیت زندگی کودکان رابطه معناداری داشت.

    بحث و نتیجه گیری

    سیاست گذاران سلامت، پزشکان و سایر اعضایی که مراقبت های درمانی را ارایه می دهند به منظور ارتقای سلامت بیماران باید دسترسی به خدمات آموزشی، درمانی و دارویی مناسب را برای کودکان مبتلا به تب و تشنج فراهم نمایند.

    کلید واژگان: تب و تشنج, توپیرامات, فنوباربیتال, کیفیت زندگی, کودکان}
    Hamid Talebianpour, Elham Talebianpour, Hamid Nemati, Khosro Keshavarz*
    Background & Objectives

    Failure to treat febrile seizure in children leads to physical, psychological and social problems and if not treated timely, might lead to epilepsy which affects the quality of life of children. The purpose of this study was to compare the therapeutic effects of two drugs on the quality of life of children under five with febrile convulsion.

    Methods

    This was a descriptive-analytical study that was done in an interventional manner. In this study, the quality of life of 40 children with febrile convulsion treated with topiramate and 51 children who had the same problem and treated with phenobarbital drug were compared. Data collection tool was EQ5D questionnaire. ANOVA and t-test were used for statistical analysis and data were entered into SPSS statistical software version 22.

    Results

    Mean scores of quality of life in children taking phenobarbital and topiramate were 72.5 and 82.7, respectively. Topiramate had a significant effect on the mean score of quality of life in children with febrile convulsion and increased it. Parental education and early febrile convulsion had a significant relationship with patients' quality of life. 

    Conclusion

    Health policy makers, physicians, and other members of health care system must provide access to appropriate educational, medical, and therapeutic services for children with febrile seizure in order to improve their health status.

    Keywords: Febrile convulsion, Topiramate, Phenobarbital, Quality of Life, Children}
  • Mojtaba Kamali Aghdam, Mansour Sadeghzadeh, Sahar Fakhimi, Kambiz Eftekhari *
    BackgroundFebrile convulsion (FC) is the most common neurological problem in children which can occur in 2 to 5% of this population. The most important issue is to identify the cause of fever and rule out bacterial meningitis. The purpose of this study was to evaluate the association of aseptic meningitis due to Measles-Mumps-Rubella (MMR) vaccine in admitted children with febrile convulsion.
    Materials and MethodsThis study was a retrospective cross-sectional. Children aged 6 months to 5 years old with FC that admitted to Mousavi Hospital in Zanjan, Iran, during one year (from 2016 to 2017) were enrolled. The demographic information of patients and laboratory parameters of meningitis in their CSF fluid were recorded in a researcher made questionnaire.
    ResultsA total of 275 children were admitted due to FC. Of these children, 36.3% had respiratory infections, 33.8% nonspecific febrile infections, 16% gastroenteritis, 5.8% urinary tract infection, 5.1% acute otitis media and 2.2% meningitis. All cases of meningitis were aseptic without evidence of bacterial compromise. There was a significant relationship between the age of febrile convulsion and meningitis (P=0.012). The age of children with meningitis were between 385 to 395 days (equivalent one year and 20- 30 days), which coincide with 20 to 30 days after receiving the MMR vaccine.
    ConclusionIn the study, all cases of meningitis occurred 20 to 30 days after the MMR vaccine at one year of age. It is strongly suspected the association between aseptic meningitis and the MMR vaccine. LP is recommended in children with febrile convulsions in this age range.
    Keywords: Aseptic meningitis, Children, Febrile convulsion, Measles-Mumps-Rubella vaccine}
  • رسول کرمانی، فاطمه مسلمی، جعفر نصیری، رویا کلیشادی
    مقدمه
    تشنج ناشی از تب (Febrile convulsion یا FC)، شایع ترین اختلال مغز و اعصاب در اطفال است که با بالا رفتن حرارت بدن در کودکان 6 ماهه تا 5 ساله اتفاق می افتد و شیوع 4-3 درصد دارد. هدف از انجام این مطالعه، بررسی ویژگی های اپیدمیولوژیک، دموگرافیک و بالینی کودکان مبتلا به FC در اصفهان بود.
    روش ها
    این مطالعه ی گذشته نگر، بر روی کودکانی که در سال های 93-1390 با تشخیص FC در بیمارستان های آموزشی دانشگاه علوم پزشکی اصفهان بستری شده بودند، انجام شد. کلیه ی ویژگی های اپیدمیولوژیک، دموگرافیک و بالینی بیماران از پرونده ها استخراج و ثبت گردید.
    یافته ها
    در این مطالعه، پرونده ی 1218 بیمار مبتلا به FC با میانگین سنی 50/16 ± 33/24 ماه تحت بررسی قرار گرفت که 8/58 درصد پسر بودند. در مجموع، 0/81 درصد از موارد تشنج، از نوع ساده و 0/19 درصد از نوع کمپلکس بود. در 8/21 درصد، سابقه ی قبلی FC دیده شد و 4/26 درصد، سابقه ی فامیلی مثبت FC داشتند. بیشترین شیوع FC در فصل زمستان بود و حدود 0/10 درصد از کودکان سابقه ی بستری در دوران نوزادی داشتند. 0/34 درصد از کودکان به صورت زایمان طبیعی و 0/66 درصد به صورت سزارین به دنیا آمده بودند. بین نوع FC با نوع زایمان و سابقه ی فامیلی FC رابطه ی آماری معنی داری وجود داشت. بین عود FC با جنس، فصل و سابقه ی فامیلی FC رابطه ی معنی داری مشاهده شد.
    نتیجه گیری
    در مطالعه ی حاضر، FC در جنس پسر، در دو سال اول زندگی و در فصل زمستان شیوع بیشتری داشت. فراوانی تشنج کمپلکس در کودکانی که به صورت سزارین به دنیا آمده بودند و همچنین در کودکانی که سابقه ی فامیلی FC داشتند، بیشتر بود. سابقه ی فامیلی مثبت نیز فراوانی عود FC را افزایش می داد. شناخت عوامل مرتبط با عود FC، می تواند در پیش گیری و درمان آن کمک کننده باشد.
    کلید واژگان: تشنج ناشی از تب, فراوانی, عوامل خطرزا, کودکان}
    Rasool Kermani, Fatemeh Moslemi, Jafar Nasiri, Roya Kelishadi
    Background
    Febrile convulsion (FC) is the most common neurologic disorder in children. It occurs in children aged 6 months to 5 years, with a prevalence of 3-4%. This study aimed to evaluate the epidemiologic, demographic, and clinical features in children with febrile convulsion in Isfahan City, Iran.
    Methods
    This retrospective study was conducted in children with febrile convulsion, who were hospitalized in teaching hospitals affiliated to Isfahan University of Medical Sciences, Isfahan, Iran. Epidemiologic, demographic, and clinical variables were excluded from patient's records.
    Findings: 1218 patient's records with mean age of 24.33 ± 16.5 months were evaluated; 58.8% of them were boys. Overall, 81% of febrile convulsions were simple and 19% were complex. 10 percent had a history of neonatal hospital admission. In total, 34% and 66% were delivered by normal vaginal delivery and cesarean section, respectively. There was significant correlation between type of febrile convulsion and family history of it and childbirth type. Recurrence of febrile convulsion was related to gender, season, and family history of febrile convulsion significantly.
    Conclusion
    Febrile convulsion was more prevalent in boys, in the first two-years of life, and in winter. Complex febrile convulsion was more prevalent in children with cesarean section delivery and positive family history of febrile convulsion. The positive family history of febrile convulsion increased the risk of its recurrence. Identifying factors related to recurrent febrile convulsion may help in prevention and treatment modalities.
    Keywords: Febrile convulsion, Frequency, Risk factors, Children}
  • Mahbobeh Sajadi, Sharareh Khosravi*
    Background
    Febrile convulsion in children is a frightening experience for the mothers. This experience may have unknown aspects, which must be investigated in order to plan better support for the mothers and children. This study is conducted with the aim of exploring the experiences of mothers whose children suffer from febrile convulsion.
    Methods
    This study was based on a qualitative content analysis. 12 mothers in Amir Kabir hospital of Arak city participated in the study and shared their experiences through semi structured interviews. The gathered data were analysed using Graneheim and Lundman’s (2004) method.
    Results
    Exploring the experiences of mothers whose children suffered from febrile convulsion reflected three themes: perceived threat, seeking solution, and difference in adaptation.
    Conclusion
    Regarding the findings of this study, comprehensive supportive care plans can be designed for enabling the mothers to better cope with their children’s febrile convulsion.
    Keywords: Febrile convulsion, Child, Mother, Experience, Qualitative research}
  • Ladan Afsharkhas, Nasrin Hoseinynajad *
    Background And Objectives
    Febrile convulsion (FC) is the most common seizure disorder in childhood period. Some studies have suggested association between seasons and occurrence of FC. This study was designed to determine demographic features, causes and seasonal variations in cases with FC.
    Method
    In this descriptive, cross sectional study, 282 children 6- 60 months with FC were admitted to the Neurology ward of Ali-Asghar Children’s Hospital from 2009–2013.They were evaluated about age, gender, type (simple, complex), and recurrence of seizures, family history of FC and epilepsy, diseases and seasons on admission.
    Findings: A total of 282 patients with diagnosis of FC were admitted to our center. Of these 282 patients, 175 (62%) were male. The mean (SD) age was 24.34±14.64 months. There were simple, complex, and recurrent FCs in 208 (74%), 74 (26%) and 58 (21%) of patients, respectively. Positive family history of FC was found in 83(29.5%) and epilepsy in 38(13.5%) of cases. The disease affected 212 (75%) of cases with respiratory and 70 (25%) of cases with non-respiratory manifestations. Most patients admitted in winter.
    Conclusion
    According to our findings, FCs have seasonal pattern associated with febrile respiratory events.
    Keywords: Child, Febrile Convulsion, Season}
  • نوشین تقی زادگان، سیما افشارنژاد *، حسین عباسپور
    مقدمه
    تشنج ناشی از تب یک اختلال عصبی شایع در کودکان است. فرضیه های مختلفی در مورد استرس اکسیداتیو و هم چنین تغییرات عناصر کمیاب و نقش آن ها در پاتوژنز تشنج ناشی از تب وجود دارد. با توجه به نقش محافظتی سلنیوم به عنوان آنتی اکسیدان در سیستم دفاعی بدن، این مطالعه با هدف مقایسه سطح سرمی سلنیوم در هر دو گروه کودکان سالم و کودکان مبتلا به تشنج ناشی از تب انجام شد.
    مواد و روش ها
    در این مطالعه موردی-شاهدی مقایسه 36 کودک مبتلا به تشنج ناشی از تب با 36 کودک سالم که تقریبا در شرایط سنی و جنسی یکسان سازی شده بودند انجام گرفت. سطح سرمی سلنیوم با دستگاه جذب اتمی کوره اندازه گیری شد.
    یافته های پژوهش: میانگین سطح سرمی سلنیوم در گروه بیمار μg/L28/19±58/89 و در گروه سالم μg/L70/17±09/101 بود. به طوری که در تجزیه و تحلیل آماری مشاهده شد میانگین سطح سرمی سلنیوم در گروه بیماران به طور معناداری کمتر از گروه سالم است. هم چنین میانگین سطح سرمی سلنیوم با پارامترهای دموگرافیک از قبیل سابقه خانوادگی تشنج، سن، جنس و دمای بدن بیمار رابطه آماری معنی داری نشان نداد.
    بحث و نتیجه گیری
    با بررسی یافته های مطالعه حاضر می توان نتیجه گرفت که در کودکان مبتلا به تشنج ناشی از تب نسبت به گروه سالم کاهش سطح سلنیوم وجود دارد از این رو محتمل است این عنصر به عنوان یک فاکتور موثر در ایجاد بیماری تشنج ناشی از تب نقش داشته باشد.
    کلید واژگان: تشنج ناشی از تب, سلنیوم, سرم}
    Nooshin Taghizadegan, Sima Afsharnezhad *, Hossein Abbaspour
    Introduction
    Febrile convulsion is a common neurological disorder in children. There are various hypotheses about oxidative stress, changes in rare elements and their role in the febrile convulsion pathogenesis. According to the protective role of selenium as an antioxidant in the body's immune system; this study aimed to compare the selenium level in febrile convulsion cases and healthy children.
    Materials and Methods
    In this case-control study 36 children with febrile seizure were compared with 36 healthy controls whose were almost matched for age and sex. The serum selenium level was measured with the atomic absorption spectrometer.
    Findings: The average levels of selenium in patients and healthy subjects were 89/58±19/28 µg/L and 101/09±17/70 µg/L, respectively. As the statistical analysis showed, average levels of selenium in patients was significantly lower than the healthy group. Also, there was no statistically significant relationship between the mean serum selenium level and demographic factors such as family history of seizures, age, sex, and body temperature of the patient.
    Discussion &
    Conclusions
    With evaluation of the present study it can be concluded that there is selenium deficiency in children with febrile convulsioncompared to healthy children. Therefore this element may have a remarkable role in febrile convulsion disease.
    Keywords: Selenium, Febrile convulsion, Serum}
  • Nahid Rahimzadeh *, Amir Valizadeh
    Background And Objective
    Febrile convulsions (FC) are the most common seizure disorder in children. Lumbar puncture should be considered in any case with FC who is suspected to intracranial infections. This study determined white blood cell and polymorphonuclear cell counts, and protein and glucose levels in cere-brospinal fluids (CFS) of children hospitalized with FC.
    Methods
    In this cross sectional study, lumbar puncture samples of children with FC admitted to the Neurol-ogy ward of Ali-Asghar Children’s Hospital from 2010–2013 were evaluated. Recorded data included age, sex, type of seizure (simple, complex), frequent attack of FC, family history of FC or epilepsy and cerebrospinal indices (white blood cell, protein and glucose).
    Results
    In this study, 91 CSF specimens of patients with FC were evaluated. Mean (SD) age of cases was 17.66±10.81 months. Fifty seven (62.6%) of cases were male. Mean glucose and protein levels of CSF was 62.57±12.30 and 21.34±9.52 milligram per deciliter, respectively. Median of WBC and PMN count of CSF were 1 and 0 cell/mm3, respectively. There was not significant relationship between patient's characteristics and CSF indices (P >0.05).
    Conclusion
    During FCs, glucose and protein levels of CSF are in normal limits. Minimally changes may occur in CSF cell counts.
    Keywords: Febrile Convulsion, Cerebrospinal fluid (CFS), Children}
  • Ladan Afsharkhas, Nasrin Hoseinynejad, Zohreh Kalbassi, Nasrin Khalessi *
    Background And Objective
    Febrile convulsions (FC) are the most common seizure disorders in children. Lumbar puncture should be considered in any case with FC who is suspected to intracranial infections. This study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (CFS) of children that were hospitalized with FC.
    Methods
    In this cross sectional study, lumbar puncture samples of children with FC admitted to the Neurology ward of Ali-Asghar Children’s Hospital from 2010–2013 were evaluated. Recorded data included age, sex, type of seizure (simple, complex), frequent attack of FC, family history of FC or epilepsy and cerebrospinal indices (white blood cell, protein and glucose).
    Results
    In this study, 91 CSF specimens of patients with FC were evaluated. Mean (SD) age of cases was 17.66±10.81 months. Fifty seven (62.6%) of cases were male. Mean glucose and protein levels of CSF was 62.57±12.30 and 21.34±9.52 milligram per deciliter, respectively. Median of WBC and PMN count of CSF were 1 and 0 cell/mm3, respectively. There was not significant relationship between patient's characteristics and CSF indices (P >0.05).
    Conclusion
    During FCs, glucose and protein levels of CSF are in normal limits. Minimally changes may occur in CSF cell counts.
    Keywords: Febrile Convulsion, Cerebrospinal fluid (CFS), Children}
  • Kokab Namakin, Mahmoud Zardast, Gholamreza Sharifzadeh, Samaneh Bidar, Toktam Zargarian
    Objective
    Febrile seizure (FS) is one of the most common neurological problems during childhood.Pathogenesis of febrile convulsion is unknown. This study investigated some trace elements among children admitted with FS compared with thoseof febrile without seizure attacks.
    Materials and Methods
    This case-control study was conducted on48 children (6 months to 5 yr old) diagnosed with febrile seizure as the cases and 48 age-matched febrile children as the control group. Serum levels of magnesium, calcium, sodium, potassium, and serum zinc were measured. Statistical analysis was performed with SPSS (version 15) using Student t-test.
    Results
    There were no significant differences between the cases and controls in terms of gender or age. The means of serum level of zinc, sodium, calcium and magnesium in the case group was lower than those of the control group. There was no significant difference onserum potassium mean level between the case and control groups.
    Conclusion
    Deficiency of trace elements was correlated significantly with febrile convulsion, while further investigations on trace elements are required.
    Keywords: Zinc, Sodium, Calcium, Magnesium, Febrile convulsion, Children}
  • Nahid Khosroshahi, Laleh Ghadirian, Kamyar Kamrani
    Evaluation of magnesium levels in serum and cerebrospinal fluid of patients with febrile convulsion (FC) hospitalized in Bahrami hospital in Tehran in 2010-2011. In the past, decreased levels of magnesium in serum and CSF of patients with FC were reported. The purpose of this study was to identify the possible role of magnesium in febrile seizures in children. Identifying this condition, we may control seizures and also prevent subsequent convulsion. In this cross-sectional study, inclusion criteria were the existence of convulsion due to fever and exclusion criteria were having a known neurological disease which could induce a seizure, and children younger than one month. In each group (cases include children with febrile convulsion and controls include febrile children without convulsion), Mg was measured in blood, and cerebrospinal fluid of 90 children and then they were compared. The data were analyzed by SPSS (α=0.05). The mean serum and CSF levels of Mg in case and control groups were equal (P<0.87 and P<0.22 respectively). There was no difference between two groups in terms of sex, but mean age was significantly different (P<0.003). There was not an association between serum and CSF levels of magnesium and the presence of FC. Therefore, it’s not suggested to measure the level of magnesium in serum or CSF in children with fever routinely.
    Keywords: Febrile convulsion, Serum magnesium, Cerebrospinal fluid magnesium, Children}
  • Mohammad Mehdi Houshmandi, Ali Reza Moayedi, Mohammad Bagher Rahmati, Abdulmajid Nazemi, Darioush Fakhrai, Shahram Zare
    Objective
    Febrile Convulsion (FC) is occurred in 6 months to 5 yr old children. The aim of this study was to investigate the prevalence of HHV-6 infection in FC admitted patients of Bandar Abbas Children Hospital, southern Iran.
    Materials and Methods
    In a cross-sectional study, 118 children aged 6-60 months who had FC were selected by a simple random method in 2010-11. Demographic data, clinical manifestation and two blood samples gathered to assess the human herpes virus type 6 (HHV6). Blood sample obtained at the time of admission and 10 days after the first examination. ELISA was used to detect HHV-6 IgG. The subjects were studied in two groups with and without infection of HHV-6. Two groups were compared by t-test and X2.
    Results
    Fifty-three subjects completed the study, including 30 boys (56.6 %) and 23 girls (43.4%). The HHV-6 infection was detected in 23 patients out of 53 studied subjects. The mean of age for the groups with and without HHV-6 infection was 19.7±9.7 and 20.4±10.2 months old, respectively. The most common clinical presentation in both groups was rhinorrhea, diarrhea, vomiting and lethargy without any significant difference between two groups. Five patients (21.7%) in HHV-6 group and 1 patient (3.3%) in HHV-6 negative group had postictal phase more than 15 minutes (P 0.05). Convulsion within 1 hour from beginning of fever was more frequent in HHV-6 infection group than the other group (P<0.01).
    Conclusion
    There was not any difference in terms of age group, gender and clinical manifestation of infected and non-infected children with FC. Postictal phase and seizure during 1 hour after the fever were significantly different between two groups.
    Keywords: HHV, 6, Children, Febrile convulsion}
  • محمد اسماعیلی، فاطمه قانع شعرباف، نجمه اسدی، مرجان اسماعیلی
    مقدمه
    علائم عفونت ادراری در سنین مختلف متفاوت است. هرچه سن کودک کمتر باشد این علائم غیر اختصاصی تر است. هدف از این مطالعه بررسی شیوع عفونت ادراری در کودکان مبتلا به تب و تشنج است.
    روش کار
    در این مطالعه توصیفی آینده نگر، کودکان با سن 6 ماه تا5 سال مبتلا به تشنج همراه با تب که در سال 1390-1391 در بیمارستان های دکتر شیخ و قائم مشهد بستری شدند. پس از اقدامات لازم جهت کنترل تشنج، شرح حال و معاینه فیزیکی کامل، نمونه ادراری جهت کامل و کشت ادرار به آزمایشگاه فرستاده شد.
    نتایج
    در این مطالعه 596 کودک مبتلا به تشنج همراه با تب شامل 299 نفر دختر (2/50%) و 297 نفر پسر بودند (8/49%). میانگین سنی 13 ماه بود. در 49 مورد عفونت ادراری وجود داشت (5 نفر پسر، 44 نفر دختر). در 507 مورد تشنج از نوع تب و تشنج ساده بود. FC همراه با UTI ارتباط معنی داری با جنس (دختر)، سن (زیر 24 ماه) و روز وقوع تشنج همراه با تب (تب با مدت کمتر از 24 ساعت) داشت ولی با نوع تشنج، سابقه تشنج و شدت درجه حرارت ارتباط معنی داری نداشت.
    نتیجه گیری
    با نوع به غیر اختصاصی بودن علائم عفونت ادراری در شیرخواران و شایعتر بودن عفونت ادراری در این دوره سنی توصیه می شود که در کودکان دختر زیر 2 سال که دچار تب و تشنج شده اند لزوما آزمایش کامل ادرار و کشت ادرار به منظور تشخیص عفونت ادراری انجام شود.
    کلید واژگان: تب, تشنج, کودکان, عفونت ادراری}
    Mohammad Esmaeili, Fatemeh Ghane, Najme Asadi, Marjan Esmaeili
    Introduction
    Urinary tract infection (UTI) is a common childhood bacterial infection second to upper respiratory tract infection. Kidneys scar، hypertension and chronic kidney disease are grave complications due to urinary tract infection in pediatric age group. Clinical manifestations of UTI in infancy are nonspecific، therefore، UTI should be considered in any child with fever. The aim of this study was to evaluate incidence of UTI in children with febrile convulsion (FC) and to provide a protocol for urinary tract infection work up. Subjects &
    Methods
    All children aged 6 months to 5 years old with FC admitted in emergency wards in two teaching hospital، worked up for UTI، by urinalysis and urine culture. Leukocyturia with positive urine culture was labeled as UTI. Bacterial colony count ³104/ ml urine in sample bag or clean catch midstream urine sample and any colony in suprapubic urine sample were considered as positive urine culture.
    Results
    Mean age of 596 children with FC (including 299 girls، 297 boys) was 13 months، 507 cases had simple FC. UTI was detected in 5 boys and 49 girls. FC associated with UTI had significant statistical correlation with gender (girl)، age (less than 24 months) and occurrence date of FC due to fever (FC occurrence in first 24 hours of fever). There were no statistical correlations with type of FC، history of FC and severity of body temperature.
    Conclusion
    Urinary tract infection is common in infantile period with non specific clinical manifestations. We recommended working up all female children with FC for urinary tract infection in order to appropriate diagnosis and treatment، more follow up and checking including VCUG and isotope DMSA scan. Acknowledgement: This study was supported by a grant from the Vice chancellor for research of the Mashhad University of Medical Sciences for the research project as a resident thesis with approval number of 87783. We would like to thank Ms. Saeide seyed hoseini for typing of the manuscript. The authors have no conflict of interest.
    Keywords: Urinary tract infections, children, Febrile Convulsion, Fever, Convulsion}
  • Mohammad Mehdi Nasehi, Roya Sakhaei, Mahmood Moosazadeh*, Maryam Aliramzany
    ObjectiveSeveral factors are involved in the etiology of febrile seizure (FS), among themis zinc (Zn), which has been discussed in various studies. The present systematic review compares Zn levels in children with FS and a control group.Materials & MethodsWe searched keywords of febrile seizure, febrile convulsion, children, childhood,fever, trace elements, risk factor, predisposing, zinc, Zn, and epilepsy in thefollowing databases: SCOPUS, PubMed, and Google Scholar. The quality ofresearch papers was assessed using a checklist. Data was extracted from primarystudies based on demographic variables and amounts of Zn in case and controlgroups.ResultsTwenty primary studies were entered in the present study. Of which, eighteenstudies, reported that Zn serum levels were significantly lower in the case group(patients with FS) than the control group.
    Conclusion
    The present systematic review indicated that Zn is one factor for predicting FS. A low level of this element among children can be regarded as a contributing factor for FS, a conclusion with a high consensus among different studies carried out in different parts of the world.
    Keywords: Febrile seizure, Febrile convulsion, Zinc, Trace elements, Systematic review}
  • زینب طاهری، مسعود ریانی*، ژیلا سلطان احمدی، بتول پورابولی، زینب موحدی
    زمینه و هدف
    تشنج ناشی از تب شایع ترین اختلال نورولوژیک در کودکان شش ماه تا شش سال است. با توجه به امکان عود این بیماری و نقش مهم مادر در کنترل آن، مطالعه حاضر با هدف بررسی تاثیر برنامه آموزشی کنترل تشنج ناشی از تب بر دانش، نگرش، نگرانی و عملکرد مادران کودکان مبتلا به تشنج ناشی از تب انجام گرفت.
    مواد و روش ها
    این مطالعه نیمه تجربی بر روی 130 مادر دارای کودک مبتلا به تشنج ناشی از تب با روش نمونه گیری دردسترس در بیمارستان آموزشی وابسته به دانشگاه علوم پزشکی شهرکرد در سال 1392 انجام گرفت. واحدهای پژوهش به روش تصادفی به دو گروه مداخله و کنترل تخصیص یافتند. ابزار جمع آوری اطلاعات شامل چهار پرسش نامه دانش، نگرش، نگرانی و عملکرد بود. قبل و بعد از اجرای برنامه آموزشی، اطلاعات با استفاده از پرسش نامه های مذکور جمع آوری گردید. داده ها با استفاده از آزمون های تی زوجی، تی مستقل و رگرسیون چندگانه در نرم افزار آماری SPSS نسخه 20 تجزیه و تحلیل شد.
    یافته ها
    نتایج آزمون تی مستقل نشان دهنده وجود اختلاف معنی دار میانگین نمرات دانش، نگرش، نگرانی و عملکرد مادران پس از مداخله آموزشی در گروه مداخله بود (0/001 > P). نتایج رگرسیون چندگانه نیز نشان داد که بین نگرش مادران با سن مادر (0/009 = P) و رتبه تولد کودک (0/010 = P)، بین نگرانی مادر با سن کودک (0/040 = P) و عملکرد مادر با شغل مادر (0/040 = P) ارتباط معنی داری وجود داشت.
    نتیجه گیری
    مداخله آموزشی می تواند منجر به افزایش دانش، بهبود نگرش و عملکرد و کاهش نگرانی مادران در زمینه پیشگیری از تشنج ناشی از تب گردد. بنابراین پیشنهاد می شود، برنامه های آموزشی مناسب برای مادران در دستور کار پرستاران قرار گیرد.
    کلید واژگان: تشنج ناشی از تب, برنامه آموزشی, دانش, نگرش, عملکرد, نگرانی}
    Zeinab Taheri, Masoud Rayyani *, Jila Soltanahmadi, Batool Pouraboli, Zeinab Movahedi
    Background And Objective
    Febrile convulsion is one of the most common neurologic disorders in children aged 6 months to 6 years. Considering the probability of recurrence and the crucial role of mothers in controlling the disease, we conducted the present study to explore the effectiveness of a febrile convulsion control educational program on the knowledge, attitude, anxiety, and action of mothers.
    Materials And Method
    This quasi-experimental study was performed in Shahrekord, Iran, on 130 mothers of children who had experienced febrile convulsion in 2013. The participants were selected using convenience sampling method and randomly divided into two intervention and control groups. The data were gathered before and after the educational program using demographic, knowledge, attitude, anxiety, and action questionnaires. The data were analyzed using SPSS software version 20, Student's independent t-test, paired t-test, and multiple regression tests.
    Results
    The results of Student's independent t-test showed a significant difference in mean scores of knowledge, attitude, anxiety, and action (P < 0.001) The results of multiple regression tests showed a significant correlation between mother's attitude and their age (P = 0.009) and child's birth order (P = 0.010), between mother's anxiety and child's age (P = 0.040), and the mother's action and their occupation (P = 0.040).
    Conclusion
    This study confirmed the efficiency of educational interventions in increasing knowledge, improving attitude and action, and reducing anxiety of mothers regarding prevention of febrile convulsion in children. Therefore, it is proposed that conducting appropriate educational programs for mothers be added to the job description of nurses.
    Keywords: Febrile convulsion, training program, knowledge, attitude, action, anxiety}
  • Mahmut Abuhandan, Abdullah Solmaz, Suleyman Geter, Cemil Kaya, Ilhan Yetkin, Bulent Koca
    Objective
    This study aimed to evaluate serum selenium levels and mean platelet volume in children who experience simple febrile convulsion.
    Methods
    The study comprised 42 patients diagnosed with simple febrile convulsions and a control group of 30 healthy children. Blood samples were taken following a febrile convulsion. Selenium levels in the serum of both the patients and control subjects were measured with the hydride formation method on an atomic absorption spectrometry device and mean platelet volume was evaluated.
    Findings
    When the mean values of the febrile convulsion patients were compared with those of the control group, the mean selenium levels and thrombocyte count were found to be statistically significantly low (P=0.002, P=0.01 respectively) and the mean platelet volume values were statistically significantly high (P=0.002).
    Conclusion
    While low serum selenium levels cause the onset of a febrile seizure in patients with simple febrile convulsion, it is thought that the increased mean platelet volume shows infection activity causing febrile convulsion.
    Keywords: Febrile Convulsion, Selenium, Platelet: Mean Platelet Volume, Antioxidant}
نکته
  • نتایج بر اساس تاریخ انتشار مرتب شده‌اند.
  • کلیدواژه مورد نظر شما تنها در فیلد کلیدواژگان مقالات جستجو شده‌است. به منظور حذف نتایج غیر مرتبط، جستجو تنها در مقالات مجلاتی انجام شده که با مجله ماخذ هم موضوع هستند.
  • در صورتی که می‌خواهید جستجو را در همه موضوعات و با شرایط دیگر تکرار کنید به صفحه جستجوی پیشرفته مجلات مراجعه کنید.
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