جستجوی مقالات مرتبط با کلیدواژه "frozen sections" در نشریات گروه "پزشکی"

This study aimed to determine the diagnostic values of frozen section compared with permanent pathology results for detection of characteristic of head and neck tumors.
In a cross-sectional study, 88 patients suffered from head and neck tumors and operated during 2010-2015 in Alzahra hospital, Isfahan, Iran, were enrolled. The results of frozen section and permanent pathology were extracted from hospital records and sensitivity, specificity, false negative, false positive, and negative and positive predictive values were calculated for frozen section.
Findings: Sensitivity, specificity, false negative, false positive, positive predictive value, and negative predictive value were as 89.8%, 94.4%, 5.6%, 10.2%, 95.7%, and 87.2%, respectively; and the accuracy of frozen section was 91.8%.
Frozen section test during surgeries is a good and valuable method for detection of characteristic of head and neck tumors. But, enough pathologist experience and precision of sampling by surgeon can lead to increase the accuracy rate of frozen section which finally leads to decrease of reoperation and relapse of disease, and better prognosis.

Due to the short half-life of parathyroid hormone (PTH), intra-operative quick PTH measurement (immediately after removal of adenoma) is beneficial to identify and evaluate the adequacy of tissue removal and to reduce reoperation and more extensive surgery.

The aim of this study was to compare pre-and postoperative parathyroid hormone levels with frozen section during parathyroidectomy.

This analytical study was conducted on 25 patients with primary hyperparathyroidism referred to Velayat Hospital in Qazvin for parathyroidectomy during 2013. Serum PTH levels were measured before surgery and 10 minutes after surgical removal of adenomas and the results were compared with the results of frozen section during surgery. Data were analyzed using paired T-test.

Mean PTH level was 222±68.5 before surgery and was 56±57.7 after removal of the adenomas. The difference was statistically significant. These results were consistent with the results of frozen section.

With regards to the results, it seems that frozen section technique is an appropriate method to assess the surgery and to reduce the extent of surgery.

Endometrial carcinoma is considered the most common gynecological cancer in the world. Pelvic and para-aortic lymphadenectomy is widely advised based on FIGO staging system. Intra-operative frozen sections analysis is used to identify pa-tients at high risk for pelvic and para-aortic nodal metastasis evading lymphadenec-tomy in low-risk patients. However there is still some controversy concerning the effi-ciency of IFS. The aim of this study was to determine the validity and precision of fro-zen section diagnosis and gross examination of uterine specimen compared to the final histological results in patients with endometrial cancer. Patients diagnosed as endometrial cancer based on office biopsy using a Pipelle or D&C who underwent surgical staging were compared for frozen section anal-ysis and permanent diagnosis. Patients with the history of radiotherapy or other types of cancer or co existence malignancies were excluded. There was no relation between the tumor size and lymph node involvement and the results were not significant (P= 0. 1). Frozen section analysis was significantly accurate and correct in predicting final histopathological results (P< 0. 0001). It has been shown that in more than 90% of patients the diagnosis made by frozen section analysis was in accordance with final pathology with considerable sensitivity and spec-ificity. Gross examination was also precise in determining myometrial microscopic in-vasions (P< 0. 0001). Although the sample size of the studied population was small but our study results support the previous data and suggest that in early stages and low grade tumors، gross examination and frozen section diagnosis are conveniently predictive of lymph node metastasis. These data might be useful for prediction of tumor invasion using frozen section and gross examination in low grade tumors and early stages and for doing complete surgical staging and lymph node sampling. However the im-portance of surgical staging always must be considered in patients who need systemat-ic lymphadenectomy. In overall these data might help to come up with new guidelines for surgical risk assessment in endometrial cancer.

Introduction & This study was performed to determine the role of frozen section examination (FSE) of the cone specimen in the evaluation of the resection margin status and to rule out invasion in patients with high-grade cervical intraepithelial neoplasia. Twenty patients with high grade intraepithelial neoplasia undergoing conization biopsy and frozen section examination were cross- sectionally studied from March 2008 until September 2009.The results of permanent paraffin sections were compared using FSE. In this cross-sectional study, 15 out of 20 cases (75%) showed the same results in frozen and permanent sections of cone biopsy specimen. Two patients out of the remaining 5 ones had higher grade of CIN in frozen section, 2 had lower grade and one was considered the same because CIN1 in FSE was normal in permanent sections.although The Paired Sample t-test showed no significant difference between the two groups of frozen and permanent section results (P-value=0.716, CI=95%). Frozen section evaluation of cervical cone biopsy specimens in patients with CIN II-III is accurate, efficient, and cost-effective.