جستجوی مقالات مرتبط با کلیدواژه "fuo" در نشریات گروه "پزشکی"
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سابقه و هدف
تب با منشا ناشناخته (FUO)یکی از چالشهای بالینی در علم پزشکی می باشد. بطور کلی بیشترین علل FUO شاامل عوامل عفونی، بدخیمی، علل التهابی غیر عفونی و عوامل ناشناخته گزارش شده است لیکن بسته به عوامل مختلفی از جمله منطقه جغرافیایی بیماری، سن افراد و دسترسی به امکانات آزمایشگاهی و تشخیصی متغیر است. هدف از مطالعه حضار بررسی علل تب با منشا ناشناخته کلاسیک در بالغین بستری شده در بیمارستان بزرگ دزفول در سالهای 98-1397 میباشد.
روش کاردر مطالعه حاضر پرونده کلیه بالغین بستری شده در بیمارستان بزرگ دزفول با تشخیص اولیه FUO در ساالهاای 98- 1397 بررسی شد. روش جمع آوری داده بصورت گذشته نگر و با مراجعه به پرونده پزشکی بیماران و استخراج اطلاعات مورد نیاز بوده است.
یافته هابیشترین علل FUO به ترتیب شامل عوامل عفونی(50)%غیر عفونی26.1%ناشناخته13%و بادخیمی 10.9%بودناد. از بین عوامل عفونی بیشترین فراوانی مربوط به تشخیاص پنومونی (21.7 درصد)، سپسیس (21.7 درصد) و سال خارج ریاوی (17.4 درصد) بود. ابزار تشخیصی در 26 درصد بیماران تهاجمی و در 9.73 درصد غیر تهاجمی بود. ارتباط معنی داری بین علل اصلی FUO با سایر متغیرها دیده نشد.
نتیجه گیریالگوی علل FUO در مطالعه حاضر در توافق با مطالعات پیشین میباشد لیکن توصایه میشود جهت تسریع در امار تشخیص بیماران بستری با FUO در این منطقه جغرافیایی همواره بیماریهای شایع و بومی منطقه از جمله سل و تیروییدیت و نیاز تظاهرات بالینی غیر معمول سندروم های بالینی شایع مد نظر قرار گیرد.
کلید واژگان: تب با منشا ناشناخته, سپسیس, پنومونی, سل خارج ریهBackground and objectiveFever of unknown origin (FUO) is one of the clinical challenges in medicine. Most causes of FUO include infectious diseases, malignancies, non-infectious inflammatory causes, and unknown factors, but this prioritization may change under the influence of various factors such as geographic area, age, and access to laboratory-diagnostic facilities. The aim of this study was to determine the frequency of causes of FUO in this area in order to suggest a better clinical approach to achieve a faster diagnosis in patients with fever of unknown origin.
Materials and methodsIn this cross-sectional, descriptive study, we studied all files of patients who admitted to Dezful General Hospital with an initial diagnosis of FUO during 2018-2019. In descriptive statistics, for qualitative variables, frequency table (percentage) and graph and for quantitative variables, central and dispersion indices including mean and standard deviation were used.
ResultsThe most common causes of FUO were infectious agents (50%), non-infectious (26.1%), unknown (13%) and malignancies (10.9%). Among the infectious agents, the highest frequency was related to the diagnosis of pneumonia, sepsis and extra pulmonary tuberculosis. About 71% of patients are diagnosed with non-invasive methods. No significant relationship was found between the four main causes of FUO and other variables during the analysis using Chi-Square Tests.
ConclusionAlthough the pattern of causes of FUO in this study is compatible with most medical sources, but we suggest that in order to achieve a faster diagnosis of patients admitted with FUO in this area, always common and endemic diseases such as tuberculosis and thyroiditis and unusual clinical manifestations of some syndromes should be considered.
Keywords: FUO, Pneumonia, Sepsis, Extra pulmonary tuberculosis -
Background
Although infectious diseases are the most common cause of fever of unknown origin (FUO) in many countries, the spectrum of its etiology is changing over time.
ObjectivesThe purpose of this study was to determine the clinical spectrum and the pattern of FUO in Shiraz.
MethodsThis study was undertaken from 2011 to 2015 in the main hospitals of Shiraz, southern Iran. The data of 60 patients fulfilling the modified criteria for FUO referring to the main hospitals in Shiraz were used for analysis. The data were extracted from the patients’ medical charts and probable etiologies responsible for FUO were assessed. The patients were followed up by further ambulatory and readmission assessment.
ResultsOf the identified etiologies, infections were the most common cause of FUO in 30% of the patients, followed by collagen vascular diseases with 15% and malignancies with 11.6%. However, 25 patients (41%) remained undiagnosed for their fever causes.
ConclusionsThe pattern of FUO in the region has changed in recent years and complicated cases are admitted to hospitals. With improving ambulatory tests and diagnostic modalities, most of the patients with FUO are being diagnosed in outpatient settings and it will cause some changes in the classic percentage of FUO etiologies among admitted patients in the future.
Keywords: FUO, Infection, Malignancy -
IntroductionChronic recurrent multifocal osteomyelitis (CRMO) is a rare migratory skeletal disorder with non-infectious inflammatory etiology which usually causes bone pain in children and adolescents. Intermittent periods of exacerbation and remission are usually noted during the course of the disease. It is a multifocal bone disease usually involving the metaphyses of long bones. The clinical and Paraclinical findings are non-specific, and indeed CRMO is a diagnosis of exclusion based on multiple criteria.Case PresentationWe present a 6-year-old boy with multiple periods of fever, systemic inflammation and bone pain since he was 2 years old, hospitalized multiple times, received antibiotics and finally diagnosed as a CRMO case.ConclusionsCRMO should be diagnosed according to a variety of clinical and paraclinical findings. In children and adolescents with multiple bone lesions and lytic lesion, one of the differential diagnoses that should be considered is CRMO.Keywords: Chronic Osteomyelitis, Bone Lesion, FUO, Children
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International Journal of Travel Medicine and Global Health, Volume:1 Issue: 1, Summer 2013, PP 39 -41
One of the most important infectious diseases in the world is Malaria. About half of the world populations are exposed to the risk of the disease. The program for controlling and eradication of Malaria has been being conducted in our country since many years ago. One of the public health problems in the endemic and non-endemic countries is Imported Malaria which can cause new and permanent infected foci. Population movement and travelling from endemic areas can transmit the disease to the clean areas and can also transmit the drug resistant Protozoa particularly Plasmodium Falciparum. Our case study describes a 30 year old person who has travelled to India for one month. He has visited a doctor in India because of fever, chills, malaise, and has received symptomatic treatment without any specific diagnosis .After returning to Iran, the symptoms appeared again after visiting by a doctor he has hospitalized with a diagnosis of Fever of unknown origin (FUO).He was checked for three days and on the fourth day, the blood smear of the patient showed Plasmodium Vivax. Ultimately he received the appropriate treatment and was discharged from the hospital in a good condition.
Keywords: Imported Malaria, FUO, Plasmodium vivax
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