جستجوی مقالات مرتبط با کلیدواژه "gastrointestinal disorder" در نشریات گروه "پزشکی"
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Gastrointestinal disorders are one of the most common conditions among people in many societies. On the other hand, evidence shows that the prevalence of usage of complementary and alternative medicine (CAM) has increased in recent years to treat many chronic and acute conditions, which might be due to testimonies of the safety, effectiveness, and affordability of CAM. In Persian medicine (PM), medical barley water (MBW) has been known as a helpful remedy for treating some digestive illnesses. This study aimed to review the properties of MBW in Avicenna’s Canon of Medicine for the treatment of gastrointestinal disorders. So, Avicenna’s Canon of Medicine was reviewed with keywords related to this remedy. Furthermore, various databases, including PubMed, Scopus, Web of Science, Google Scholar, and SID, were searched with the keywords “barley water," “non-alcoholic beer," and “alcohol-free beer." This study showed that Avicenna’s Canon of Medicine recommends MBW for the treatment of various gastrointestinal disorders. Avicenna prescribed barley water for the treatment of bowel obstruction disease, bowel mass, intestinal ulcers, and jaundice. Oral consumption of MBW was the most frequently used method for disease improvement. Meanwhile, recent studies have also shown the therapeutic effects of non-alcoholic beer in the treatment of various disorders, such as gastrointestinal inflammatory disease, cardiovascular disease, and diabetes, possibly due to its anti-inflammatory effect. Given the high importance of MBW in Avicenna’s Canon of Medicine, the results of this review and recent clinical studies can introduce MBW as an effective and less harmful gastrointestinal drug. We suggest conducting further clinical trials to assess the effectiveness of MBW in managing gastrointestinal conditions.
Keywords: Hordeum, Gastrointestinal Disorder, Persian Medicine, Complementary Therapies, Herbal Medicine, Ma'al Sha'ir -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هشتادم شماره 3 (پیاپی 254، خرداد 1401)، صص 217 -229زمینه و هدف
عفونت هلیکوباکتر پیلوری و دستگاه تنفسی به طور همزمان باعث افزایش بیماری زایی و مرگ و میر می شود. هدف از این مطالعه، بررسی همزمانی ابتلا به مشکلات دستگاه تنفسی فوقانی و عفونت های گوارشی هلیکوباکتر پیلوری بود.
روش بررسیتحقیق حاضر به صورت یک مرور نظام مند و فراتحلیل، از شهریور 1398 تا شهریور 1399، در دانشگاه علوم پزشکی قزوین انجام شد. مقالات وارد شده در پایگاه های داده های بین المللی (آوریل 2001-دسامبر 2018)، در خصوص همزمانی ابتلا به اختلالات مجاری تنفسی فوقانی با عفونت های گوارشی هلیکوباکتر پیلوری مورد بررسی قرار گرفتند. از اثر مدل تصادفی با سطح اطمینان 95% جهت تجزیه و تحلیل داده ها استفاده شد.
یافته هابیشترین شیوع همزمانی مربوط به اختلالات تنفسی مرتبط با بافت آدنویید (33%)، پولیپ بینی (100%) و رینوسینوزیت مزمن (71%) بود. شیوع همزمانی بیماری، 53% در رینوسینوزیت مزمن، 63% در پولیپ بینی، 62% در بافت آدنویید و در کل 60% برآورد شد که معنادار بود (000/0=P). شیوع همزمانی اختلالات مجاری تنفسی فوقانی با عفونت های گوارشی هلیکوباکتر پیلوری در بیماران به میزان 61% در سن بیش از 27 سال و 60% در سنین کمتر از 27 سال برآورد شد.
نتیجه گیریشیوع همزمانی ابتلا به اختلالات مجاری تنفسی فوقانی با عفونت های گوارشی هلیکوباکتر پیلوری در بیماران با سنین بالا و پایین تقریبا به یک میزان و به صورت معناداری مشاهده شد. با توجه به اینکه وقوع همزمان بیماری ها در افراد خطرناک می باشد، غربالگری بیماران مبتلا به هریک از این بیماری ها، جهت شناسایی بیماری های دیگر و تجویز داروهای مناسب ضروری می باشد.
کلید واژگان: اختلالات گوارشی, هلیکوباکتر پیلوری, عفونت, اختلالات تنفسیBackgroundHelicobacter pylori infection and respiratory tract infection at the same time cause pathogenicity increase and death. The aim of this study was to evaluate the co-occurrence of upper respiratory tract disorders and gastrointestinal infections of H. pylori.
MethodsThe present study was conducted as a systematic review and meta-analysis, from August 2019 to Agusut 2020, at Qazvin University of Medical Sciences. Articles in the international databases (April 2001-December 2018) on the coexistence of upper respiratory tract disorders with H. pylori gastrointestinal infections were examined. The random effect model with a 95% confidence level was used to analyze the data.
ResultsThe highest prevalence of respiratory disorders co-occurrence associated with adenoid tissue (33%), nasal polyps (100%), chronic rhinosinusitis (71%) and gastrointestinal infections of H. pylori was reported in 2006 in Turkey, 2011 in Poland and 2015 in Egypt. Concurrent prevalence of the disease, according to the type of upper respiratory tract disorders in all studies, the estimated effect size according to the random model was 53% in chronic rhinosinusitis, 63% in nasal polyps, 62% in adenoid tissue and 60% in total, which was significant (P=0/000). The prevalence of co-occurrence of upper respiratory tract disorders with gastrointestinal infections of H. pylori in patients was estimated to be 61% at the age of more than 27 years and 60% at the age of fewer than 27 years. Pooled estimation of the concurrent prevalence of infection (in total) was estimated to be 60% and was significant among the studies (P=0/000).
ConclusionThe concurrent prevalence of upper respiratory tract disorders with gastrointestinal infections of H. pylori was observed to be almost equal and significant in elderly and young patients. Due to the fact that the simultaneous occurrence of two types of infections and diseases in people is very dangerous, screening of patients with each of these infections is necessary to identify the other infection and prescribe appropriate drugs.
Keywords: gastrointestinal disorder, helicobacter pylori, infection, respiratory disorders -
Introduction
Considering the increasing number of patients referred to gastroenterology clinics, we report a suspected case of coronavirus disease 2019 (COVID-19) with only gastrointestinal (GI) presentation in Qom, Iran.
Case PresentationA 74-year-old man with epigastric pain, diarrhea and vomiting for one week was treated, based on the routine abdominal treatment protocol. Since all GI symptoms were resistant to therapy, we decided to perform laboratory assays for a more accurate diagnosis of the disease. Considering the persistence of abdominal pain and nausea, abdominal and pelvic computed tomography (CT) scans, as well as endoscopy and colonoscopy, were performed. After performing the chest CT scan, we noticed the involvement of the lungs. The patient did not have any respiratory symptoms, and at the time of his hospitalization, the COVID-19 epidemic had been reported in Iran. With the progression of the disease, he started to experience mild fever (38°C). Using a specific COVID-19 kit, he was diagnosed with COVID-19 after precise evaluations. However, without any medications, all of his symptoms subsided after 2 - 3 weeks.
ConclusionsIt is important for all physicians to know that some pure GI symptoms, which are resistant to therapy, may be the only symptoms in suspected COVID-19 patients. Timely diagnosis and isolation of these patients can guarantee population to avoid the spread of this highly contagious infection.
Keywords: Pneumonia, CT Scan, RT-PCR, COVID-19, Gastrointestinal Disorder -
BackgroundEosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, including interleukin (IL)-17. This study aims to evaluate the potential role of this cytokine in the pathogenesis of EGID.Materials and MethodsThis prospective study was conducted at the Allergy Outpatient Clinic, Mofid Children Hospital, Tehran, Iran from January 2016 to January 2017. In this study, Serum IL-17 was determined in all the patients referred to the Allergy Clinic with a pathologic diagnosis of EGID.ResultsThe median (minimum and maximum) serum IL-17 level in patients with EGID, gastroesophageal reflux disorder (GERD), and healthy controls were 4.32 (0.00-6.383), 2.82 (0.00-3.231), and 3.6 (0.00-7.165) pg/mL, respectively. The results of the non-parametric analysis revealed no significant difference between the three groups regarding IL-17 (P=0.16). However, by classifying EGID in two separate groups with the involvement of upper (eosinophilic esophagitis and eosinophilic gastritis) and lower (eosinophilic enteritis, eosinophilic colitis) gastrointestinal (GI) tracts, a significant difference in serum IL-17 level became evident (P=0.004).ConclusionWe found a significant relationship between IL-17 and upper GI involvement in EGID.Keywords: Eosinophilic, Gastrointestinal disorder, Serum IL-17, Eosinophilic Gastrointestinal Disorder (EGID)
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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد، سال پنجاه و هفتم شماره 3 (پیاپی 127، امرداد و شهریور 1393)، صص 579 -586مقدمهاختلالات مزمن گوارشی، بار اقتصادی و فشار روانی زیادی را به جامعه و سیستم بهداشتی و درمانی تحمیل می کنند. از جمله این اختلالات مزمن می توان به سندرم روده تحریک پذیر اشاره کرد. هدف از انجام این تحقیق بررسی وضعیت اپیدمیولوژی سندرم روده تحریک پذیر در مشهد می باشد.روش کاراین مطالعه توصیفی مقطعی در سال 1392 بر 323 بیمار مبتلا به سندرم روده تحریک پذیر در مشهد انجام شد. روش نمونه گیری مبتنی بر هدف بود. داده های ثبت شده به نرم افزار آماری SPSS وارد و تجزیه و تحلیل شد. جهت توصیف آزمودنی ها از روش های آمار توصیفی و جهت مقایسه متغیر ها در زیرگروه ها، از آزمون های آنالیز واریانس و کروسکال والیس استفاده شد. میزان P کمتر از 05/0 معنی دار در نظر گرفته شد.نتایجزیر گروه مختلط بیشترین فراوانی و زیر گروه یبوست کمترین فراوانی را داشتند. نسبت زنان به مردان 5/1 به 1 بود و توزیع جنسیت در چهار زیر گروه تفاوت معناداری نداشت(1/0=p). طول مدت بیماری حدود 5/4 سال بود که در چهار زیر گروه به طور معناداری متفاوت بود(03/0= p). بیماران حداقل یکبار در ماه به پزشک مراجعه می کنند.نتیجه گیریویژگی های الگوی بالینی و اجتماعی در زیر گروه ها تفاوت معناداری ندارد.تعدد مراجعات بیماران به پزشک، 12 نوبت مراجعه در سال به ازای هر بیمار است و همین روزهای از کار افتادگی، هزینه اقتصادی قابل توجهی را برای افراد، جامعه و نظام سلامت ایجاد می کند.کلید واژگان: اختلالات گوارشی, سندرم روده تحریک پذیر, اپیدمیولوژی, فراوانیIntroductionChronic gastrointestinal disorders, imposes stress and large economic burden on society and the health care system. Including chronic disorders, irritable bowel syndrome can be noted. The purpose of this study was to investigate the epidemiology of irritable bowel syndrome in Mashhad for further recognition of the disease in Iranian society. Subjects andMethodsThis cross-sectional study in 2013 was conducted on 323 patients with irritable bowel syndrome. Sampling method was based on purposive. For the purposes of this study, the recorded data entered into SPSS software were analyzed. The descriptive statistical methods were used for description of the subjects, and to compare variables in subgroups of patients, parametric (analysis of variance) and nonparametric (Kruskal-wallis) tests were used. P value of less than 0.05 was considered significant.ResultsThe subtype of mixed had the highest frequency and subtype of constipation had the lowest frequency. Female to male ratio was 1.5 to 1 and gender distribution had not significant differences in four subtypes (P=0.1). Duration of disease was approximately 4.5 years that was significantly different in four subtypes (P=0.03). The patients had at least one visit to doctor every month.ConclusionClinical characteristics and social patterns were not significantly different in subgroups of IBS. Frequency of patient visiting the doctor was 12 times in a year for every patient, and these days of disability are a significant economic costs to individuals, society and the health system.Keywords: gastrointestinal disorder, Irritable Bowel Syndrome, Epidemiology, frequency
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