جستجوی مقالات مرتبط با کلیدواژه « genetic abnormalities » در نشریات گروه « پزشکی »

Currently, the use of cell therapy is an effective treatment method in some types of diseases. The use of stem cells and somatic cells, due to the complete genetic similarity with individual cells, has led to the development of cell therapy methods. In recent years, significant advances have been made in the methods of culturing, isolating, and long-term cell maintenance. However, there are still problems and concerns related to their clinical use, the resolution of which requires more detailed studies in this area. One of these problems is genomic changes in cells that can affect the potential for differentiation of stem cells. Genetic abnormalities occur during successive cultures during the process of proliferation and differentiation, and can affect cell behavior and subsequent laboratory results. The aim of this study is to investigate the importance of chromosomal studies in cell therapy for the analysis of chromosomes and summarize the applications and limitations of these methods in the medical sciences.

The results of this discussion show that the use of different techniques of chromosomal studies can be considered in the final evaluation and obtaining confirmation of the accuracy of cellular products in treatment. Periodic and regular examinations of genomic stability in cells before their clinical use are essential.

Human Genomes including genomes being effective and creative in all human behavior and physical changes have been adverted in last decade more than ever. The subject nowadays by identification of genomes’ functions and forecast possibility of their effects on aborning children and appearing the idea of prevention of their negative effects occurrence and even curbing of patient -physically and mentally- and premature humans birth is emphasized and many ethically and legally questions are formed. The official responses have been made two parts of dissidents and adherent opposing each other. Societies these days desire a healthy and free of maim, genetic abnormalities and severe diseases of the society. More chance for progress and attainment to scientific and industrial facilities will be achieved in addition of patients’ therapy and maintenance costs will be saved if society’s health and hygiene is supplied. So there is no doubt that every society’s public interests are requiring a healthy population and prevention of abnormal child birth. Ethics and law as two key elements for human life’s guide play a vital, guideline role in his general and decisive decisions. Therefore it has always been represented necessary that every new problem must be analyzed through them. At first this article is going to obtain an answer basing on analyzing of philosophical and Islamic law’s principles for the questions that between public interests and person’s tendency to farrowing abnormal child, which one has precedence? If public interests or on the other word society’s expedient can make a right for governments to prevent from abnormal and premature child? And most important than all of them, what command will be propound by moral and humanities rule? And it will be got to the result that being ethically and legally abnormal child’s abortion duration of his/her embryonic period can be taught. And more than it, we can go forward to make it mandatory.