جستجوی مقالات مرتبط با کلیدواژه « go » در نشریات گروه « پزشکی »

Cognitive control plays a role in human behavior and mental processes and affects paranormal beliefs. This study aims to investigate the role of cognitive control in paranormal beliefs using the go/no-go task.

A total of 92 people were selected based on low, middle, and high scores in the revised paranormal belief scale (R-PBS) and assigned to 3 groups. The groups included 30 severe paranormal believers (13 females with a mean age of 25.3 years), 31 mild paranormal believers (14 females with a mean age of 26.4 years), and 31 skeptics (16 females with a mean age of 25.8 years). All participants were tested on the go/no-go task. A multivariate analysis of variance was conducted with the given groups (severe paranormal believers, mild paranormal believers, and skeptics) as the independent variable and the go/no-go subscales scores as dependent variables.

The findings showed a significant difference between the mean scores in errors of go (F(2, 89)=7.20, P=0.01), errors of no-go (F(2, 89)=11.81, P=0.01), and reaction time (F(2, 89)=21.46, P=0.01) between the groups.

The severe and mild paranormal believers had lower accuracy and slower reaction times than the skeptics group. Therefore, severe paranormal believers and mild paranormal believers had a weakness in all go/no-go subscale scores. This finding suggests that paranormal beliefs may be related to poor cognitive control.

The present study aimed to determine whether bone marrow mesenchymal stem cell-derived microvesicles (MSC MVs) were effective in restoring lung tissue structure, and to assess the potential role of miRNAs in the pathogenesis and progression of acute respiratory distress syndrome (ARDS). ARDS was induced by lipopolysaccharide in male C57BL/6 mice. The degree of lung injury was assessed by histological analysis, lung’s wet weight/body weight, and protein levels in the bronchoalveolar lavage fluid (BALF). Sequencing was performed on the BGISEQ-500 platform. Differentially expressed miRNAs (DEMs) were screened with the DEGseq software. The target genes of DEMs were predicted by iRNAhybrid, miRanda, and TargetScan. Compared with LPS-injured mice, MSC MVs reduced lung water and total protein levels in the BALF, demonstrating a protective effect. 52 miRNAs were differentially expressed following treatment with MSC MVs in ARDS mice. Among them, miR‑532‑5p, miR‑223‑3p, and miR‑744‑5p were significantly regulated. Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed the target genes were mainly located in the cell, organelle, and membrane. Furthermore, KEGG pathways such as ErbB, PI3K-Akt, Ras, MAPK, Toll, and Wnt signaling pathways were the most significant pathways enriched by the target genes. MSC MVs treatment was involved in alleviating lung injury and promoting lung tissue repair by dysregulated miRNAs.

Cerebrovascular accident (CVA) refers to any kind of damage caused by direct or indirect damage to the brain and its related elements. It is estimated that about 60% of brain injury victims have a permanent disorder. The consequences of CVA include reduced movement speed, weakness, functional impairment, reduced power, and balance. The purpose of this study was to investigate the effect of a 12-week selected training protocol on motor function following brain injury. In a semi-experimental study, 30 male subjects with a mean and standard deviation of 52.2 ± 5.4 years, weight 173.2 ± 4.2 kg, and height of 78.8 ± 5.3 cm were selected purposefully and accessible with inclusion and exclusion criteria. The participants were randomly divided into experimental (n = 15) and control groups (n = 15). In order to evaluate the physical-motor performance, 10-meter walking tests, get up and go tests, and climbing stairs tests were used. The training program lasted for 12 weeks, three sessions per week, and each session for 30 - 60 minutes. Data were analyzed by independent t-test and dependent t-test using SPSS-21 software at P ≤ 0.05 level. Based on dependent t-test and covariance test, there were significant differences in all three components of motor function (10 m walk time tests, get up and go test, and stair climbing test), there was a significant increase after training in men with CVA (P = 0.00). From the findings of this study, it can be concluded that the special exercises of the present study have a positive effect on motor function parameters of male patients with CVA, so it can be recommended as one of the most important rehabilitation strategies for these patients.

Fluent speech requires inhibitory control for the modification of speech interruptions before the onset or during the speech. The current study aimed at comparing the inhibitory control skill in 6 to 8-year-old children with fluent speech and developmental stuttering.

This research is a descriptive-analytic cross-sectional study. The participants included 31 children with developmental stuttering (6-8 years old) selected based on the convenience sampling method. Also, 32 healthy children were selected from elementary schools in Tehran Province that matched in terms of age and gender with the first group. The children of two groups were selected from the same district (The fifth district) of Tehran Province. Visual Go/No-Go task was used to measure inhibitory control. The Mann-Whitney U test was used to compare the groups.

The result showed that the mean score of children with stuttering in the inhibition index was lower than normal children. According to the Kolmogorov-Smirnov test, the data distribution was not normal (P=0.042). Therefore, the parametric test of the Mann-Whitney U test was used. Despite the lower mean score of inhibition in children with stuttering than healthy children, there was no significant difference in the inhibition index between the groups (P=0.550).

The findings indicated that Children Who Stutter (CWS) had less efficiency in inhibitory control skill compared to normal children, and this problem could be because of the exacerbation or persistence of stuttering.

In our study, graphene oxide-TiO2 nanocomposite (GO/TiO2) was prepared and used for the enrichment of rutin from real samples for the first time. The synthesized GO/TiO2 was characterized by X-ray diffraction, scanning electron microscopy, and FT-IR spectra. The enrichment process is fast and highly efficient. The factors including contact time, pH, and amount of GO/TiO2 affecting the adsorption process were studied. The maximum adsorption capacity for ciprofloxacin was calculated to be 59.5 mg/g according to the Langmuir adsorption isotherm. The method yielded a linear calibration curve in the concentration ranges from 15 to 200 μg/L for the rutin with regression coefficients (r2) of 0.9990. The limits of detection (LODs, S/N=3) and limits of quantification (LOQs, S/N=10) were found to be 8 μg/Land 28 μg/L, respectively. Both the intra-day and inter-day precisions (RSDs) were < 10%. The developed approach offered wide linear range, and good reproducibility. Owing to the diverse structures and unique characteristic, GO/TiO2 possesses great potential in the enrichment and analysis of trace rutin in real aqueous samples.