جستجوی مقالات مرتبط با کلیدواژه « hemangioma » در نشریات گروه « پزشکی »

Tufted angioma is an uncommon vascular benign tumor of infancy or early childhood with slow and indolent growth. We report the case of a four-year-old boy with an asymptomatic annular lesion over the nape of the neck resembling granuloma annulare. Punch biopsy revealed multiple scattered vascular lobules or tufts. Aggregates of closely packed, dilated to compressed vascular spaces with plump endothelial cell lining were seen in the dermis, confirming the diagnosis of tufted angioma. Immunohistochemical positivity was present with CD31 and CD34 staining of endothelial cells. It is a slow-growing tumor; Kasabach–Merritt syndrome (KMS) and consumptive coagulopathy are rare complications. Blood coagulation profiles were within normal limits. In our case, the lack of reliable distinguishing characteristics of the vascular tumor and atypical annular presentation was a source of diagnostic confusion. Tenderness, typically present in tufted angiomas, was absent in our patient. This unusual case illustrates that clinicians should recognize an annular configuration as an atypical manifestation of tufted angioma.

Cavernous hemangioma is a venous malformation and intramuscular hemangioma is a rare type of hemangioma. Most of these cases are reported in masseter and temporalis muscles, and the number of patients with hemangioma involving sternocleidomastoid (SCM) muscle is relatively less. The present study reported a case of intramuscular hemangioma and a literature review regarding hemangioma in the sternocleidomastoid muscle. Case Report: The present case was a 24-year-old woman with intramuscular hemangioma of the sternocleidomastoid muscle, manifesting a mass in the right supraclavicular region involving the sternocleidomastoid muscle. The woman was treated with surgery and achieved complete treatment. After surgery, the patient was kept under regular follow-up for the last six months without any evidence of recurrence. 

Intramuscular hemangioma of the sternocleidomastoid muscle is a rare entity that can present as a mass in the neck region. The treatment approach should be considered according to the diagnosis and site of vascular malformation.

Infantile hemangioma is the most common type of vascular tumor in childhood. Risk factors for hemangioma include female gender, low birth weight, prematurity, higher maternal age, and multiple gestations. In this study, for the first time in Kerman, we describe and compare demographic features of infants with hemangiomatous lesions treated with two different systemic beta-blockers (atenolol or propranolol), examining their efficacy and adverse effects. Forty-one infants with hemangiomatous lesions admitted to the pediatric dermatology ward of Afzalipour Hospital from 2011 to 2017 were enrolled in this study. Demographic features of infants and their mothers and clinical features and complications of hemangiomatous lesions were recorded. Also, we compared the efficacy and adverse effects of treatment protocols with two betablockers (atenolol and propranolol). Most infants were female (70.7%), and 9.7% were premature. The majority of the lesions were superficial (53.7%) and located in the head and neck area (82.9%). Multiple hemangiomas were recorded in 4.8% of the cases. The most common complication was ulceration (29.3%). Two out of 18 patients treated with propranolol had a complete response rate. Adverse effects were observed more frequently with propranolol (26.8%) than with atenolol (14.6%). In our study, female gender and low birth weight were significantly more common in infantile hemangioma patients than in the normal population. Also, mothers of children with hemangioma had a significantly greater number of miscarriages than the average population. Propranolol and atenolol had no significant difference in efficacy and adverse effects.

Skull primary intraosseous cavernous hemangiomas (PICHs) are uncommon, benign, and slowgrowing tumors. These lesions are not widely known, specifically as regards the pathogenesis. The researchers wanted to describe the clinical presentations and radiological characteristics through a literature review of 140 cranial patients who received surgical treatment and histological diagnosis. Although PICH is uncommon, it should always be considered when a hard, steadily expanding skull lesion is seen. Surgical resection should be the first line of therapy for symptomatic individuals and aesthetic motivation, and their long-term results following complete removal are excellent. Moreover, we describe four patients with PICH to enrich the literature.

Objectives:

 Hemangiolymphangiomas (HLAs) are rare vascular malformations of lymphatic and blood vessels. These lesions commonly occur in the head and neck regions. In this paper, we describe a rare case of HLA, with significant effects on the mandibular bone and neurovascular canals.

Case :

A 28-year-old patient with a history of head and neck HLA was referred to an oral and maxillofacial surgeon for dental implant placement. The results of radiographic analysis and cone-beam computed tomography (CBCT) indicated the mandibular bone enlargement, sclerosis, and bone remodeling. The inferior alveolar nerve canal (IANC) and mental foramen were markedly enlarged on both sides. Additionally, multiple soft tissue calcifications were present. The patient was referred to the oral and maxillofacial surgery (OMFS) department for further dental treatment.

Conclusion:

 Patients with maxillofacial vascular malformations require careful radiographic and imaging assessments before any surgical intervention, especially implant placement. Enlargement of neurovascular canals, especially IAN and mental foramen, along with the presence of sclerotic bone, should be considered as important findings, as they may significantly influence the surgical outcomes.

Cavernous sinus hemangiomas (CSHs) are rare, benign, slow-growing neoplasms within the cavernous sinus. Laterally located to these lesions, the cranial nerves and carotid artery are subject to injury during removal of hemangiomas through a transcranial route. Therefore, for surgi- cal management of cavernous sinus hemangiomas a medial corridor granted through an endoscop- ic endonasal approach may be less traumatic to the neurovascular bundle. Case-1 describes a 23-year old male who presented with intermittent blurred vision and very mild ptosis on the right side for two years before admission. Fundoscopic exam, visual acuity and perimetry tests were normal. With intense enhancement after contrast administration, both brain MRI and CT scan demonstrated an extra-axial mass in the right cavernous sinus. Case-2 presents a 59-year-old male, a known case of renal oncocytoma who underwent nephrec- tomy a year before, with chief complain of moderate intermittent headaches. Imaging study of the brain by MRI revealed a sellar mass. Near-total resection for case-1 and gross total resection for case-2 were performed through the an extended endoscopic endonasal approach. We report two cases of near-total and gross total resection of CSHs via an extend- ed endoscopic endonasal approach substantiating advances in minimal access neurosurgery to the treatment of such grim lesions of an intricate vicinity of the skull base. At the same time, we focus to review extensively the growing yet heterogenous literature of the past twenty years on the broached topic. The evolution of extended endoscopic endonasal approach over the past two decades changes the dynamism of the surgical practices steeped in tradition and provides a safer alternate route for preserving cranial nerves of this anatomic region.

Early diagnosis of hepatic lesions can result in more successful treatment.

The present study aimed to diagnose hepatic space-occupying lesions by sonography in Guilan Cohort Center participants.

In this cross-sectional prospective epidemiological research studies of Iranian adults (PERSIAN) Guilan cohort study (Sowme'eh Sara, Guilan, Iran) conducted in 2014 - 2017, the sample included 960 individuals of both genders, aged 35 - 60 years. A radiologist examined all individuals with sonography to determine hepatic space-occupying lesions. Demographical and clinical characteristics were recorded via a questionnaire. Data analysis was performed using SPSS software (version 16).

Only 2.3% of the patients were diagnosed with hepatic lesions such as hemangioma, hepatic cysts, and other lesions with frequencies of 1.1%, 0.8%, and 0.4%, respectively. Also, there was a significant relationship between gender and the presence of hepatic lesions (P < 0.05). The frequencies of hepatic lesions were 1.7% and 3.6% in men and women and 1.6%, 2.5%, and 4.4% in the age groups of 35 - 45, 45 - 55, and over 55 years, respectively.

Hemangioma was the most common hepatic lesion diagnosed in ultrasonography examinations. Moreover, the only factor influencing the frequency of hepatic lesions was gender, which was found twice more in women than in men.

This study aims to explore the therapeutic mechanism of 32P application combined with timolol maleate for infantile superficial hemangioma.

In this study, 60 nude mice were enrolled to establish the transplantation model of infantile hemangioma in nude mice. They were randomly divided into control group, administration group and combined administration group, with 20 mice in each group. The expressions of EGFL7 and VEGF were detected by RT-PCR, and the expressions of renin and ang II were detected by Western blot.

After the administration of timolol maleate, the expression of EGFL7, VEGF, renin and Ang  II decreased (P < 0.05). The levels of EGFL7, VEGF, renin and Ang II were further down regulated by combined scheme of 32P application and timolol maleate (P<0.05).

32P application combined with timolol maleate can improve the therapeutic effect of infantile superficial hemangioma by inhibiting the expression of vascular endothelial growth factor, renin and angiotensin II.

Assessing the common oral lesions and their prevalence is important in different populations. This study assessed the prevalence of oral vascular lesions in patients referred to the Oral Medicine Department of Shiraz Dental School.  

In this cross-sectional study which was conducted in Shiraz Dental School, records of patients admitted from 2001 to 2017 were reviewed. A total of 176 patients had been diagnosed with oral vascular lesions. The mean age and gender of patients and the prevalence of vascular lesions were recorded and analyzed. Associations between the variables were explored using the Chi-square test and Kruskal-Wallis test. P<0.05 was considered statistically significant.

  A total of 176 patients had oral vascular lesions among 3,896 clinical patient records during the 16-year period (2001-2017). Of the 176 patients, 108 (61.4%) were females and 68 (38.6%) were males. The mean age at presentation was 36 ±4.5 years with an overall age range of 4-88 years. Amongst all the evaluated oral lesions, the most prevalent vascular lesion was pyogenic granuloma with 124 (3.18%) patients. Other vascular lesions were vascular malformations (n=27, 0.7%), hemangioma (n=19, 0.49%), and lymphangioma (n=6, 0.15%). There was no significant correlation between gender with vascular lesions (P=0.078) or location of lesions (P=0.143). No significant correlation was found between age with type of vascular lesion (P=0.174) or site of involvement (P=0.281).

  Among oral vascular lesions, pyogenic granuloma was found to be the most prevalent lesion in the oral cavity.

Hemangiomas are benign vascular lesions frequently observed in infancy and childhood.

A 14-year-old boy was referred to the hospital with a left-sided ear canal mass and hearing impairment. Otoscopic examination revealed a mass that occluded the canal. The transcanal surgical excision was performed. The mass was dissected from the skin, no bony erosion was noted intraoperatively, and the skin was returned back properly. The histopathological report demonstrated a capillary hemangioma of the external auditory canal. 

Hemangiomas are relatively common in the head and neck, but rarely detected in the external ear canal and tympanic membrane. Hemangioma of the ear canal may be asymptomatic and accidentally observed. Despite the rarity of the mass, it is important to consider them in the differential diagnosis of external auditory canal masses. The computed tomography and magnetic resonance imaging with gadolinium help to reveal the vascular nature of the mass. Complete surgical excision is the treatment of choice.

Liver hemangiomas are common. Giant liver hemangiomas are rare and symptomatic patients require treatment. Surgery is the curative procedure. Other options such as intra-arterial embolization may be used to decrease the volume and bleeding of these lesions. Three cases of giant liver hemangioma were treated with liver resection, one with left lateral hepatectomy and two with right lateral hepatectomy. All patients had made an uneventful recovery with no recurrence at 3-year follow-up. Most hemangiomas are small, asymptomatic, and do not require any treatment. Liver resection is a safe and effective treatment for giant hemangiomas.

Hemangiomas are benign tumors that are very common in the head and neck region. However, intravascular hemangiomas are very rare. Hemangiomas are classified as capillary, cavernous or mixed tumors according to the proliferating cells. Ultrasound, computed tomography, MR imaging and angiography are useful diagnostic tools and are generally required when planning surgical treatment. Definitive diagnosis is established by histopathological examination, differentiating hemangiomas from other vascular tumors or malignancies.  

We present a rare case of capillary hemangioma protruding from the external jugular vein. In our patient, the tumor was totally removed under local anesthesia. No complications and no recurrence were observed in the following two years.  

Intravascular tumors can present as neck masses and a definitive diagnosis is made by histopathological examination. Imaging tools provide important information about anatomy, the extent of the tumor, and for surgical planning.

Hemangioma is a benign vascular lesion, which is common in the head and neck but rare in the oral cavity. Oral hemangioma presents as a smooth, soft, painless mass, which may be sessile or pedunculated in any size. However, most of the lesions will diminish spontaneously. Several therapeutic approaches are used for hemangiomas, such as cautery, cryotherapy, laser therapy, and sclerosing agents. Herein, we reported the case of a 36-year-old female who had a swelling on the top of her upper lip since birth. We proposed laser therapy as an efficient treatment plan because of its benefits, such as the achievement of coagulation, comfort for both practitioner and patient, and esthetic advantages. Moreover, this approach eliminates the chance of recurrence if performed perfectly.

Infantile fibrosarcoma is a rare soft-tissue neoplasm, which may render a diagnostic challenge leading to misdiagnosis and consequently an inappropriate treatment of patients. This study reports a case of infantile fibrosarcoma that mimicked a hemangioma in an 11-month-old girl. As the lesion signal in the MRI was not consistent with the diagnosis of hemangiomas, we performed a core needle biopsy, which its result was consistent with the diagnosis of infantile fibrosarcoma. The lesion was initially treated with surgical resection. However, the lesion recurred one year after the surgery. The recurrence was managed with debulking surgery. The fifth finger was necrotized during the hospitalization after the relapse surgery. Finally, the necrotic finger was amputated. Also, adjuvant chemotherapy was used to prevent further relapses. The 1-year follow-up of the patient was recurrence-free. These findings highlight the importance of considering infantile fibrosarcoma when an infant presents with a lesion that clinically mimics a vascular lesion.

Hemangiomas are defined as soft tissue lesions in the maxillofacial or oral region. Hemangiomas of salivary glands constitute 30% of the non-epithelial tumors in major salivary glands.  Benign tumors in salivary glands are located 85% in parotid gland and 13% in submandibular gland. We present a case of submandibular hemangioma in an infant patient that had some complications and a challenging diagnosis. A 3- month-old female patient presented a giant hemangioma located in the submandibular, preauricular and right malar region with purplish color that during hospitalization had a cardiorespiratory arrest as a severe complication of the disease.

Over the past two decades, we have witnessed the increasing use of photodynamic therapy (PDT) in the field of ocular oncology. Based on a review of the literature and our own experience, we herein review the role of PDT for the management of intraocular tumors. The discussion includes two main topics. First, we discuss the application of PDT for benign tumors, including circumscribed choroidal hemangioma, choroidal osteoma, retinal astrocytoma, retinal capillary hemangioma (retinal hemangioblastoma), and retinal vasoproliferative tumor. Second, we assess the role of PDT for malignant tumors, including choroidal melanoma and choroidal metastasis.

Peripheral hemangioma is a benign congenital lesion and when involving the tongue, it does not appear on panoramic radiography.

This case report describes a 29-year-old male patient with peripheral hemangioma in his tongue and left side of the lower lip. In panoramic radiography, some calcifications are seen. In cone beam computed tomography (CBCT), more calcifications (phleboliths) and mandibular thinning are seen and if the lesion is not excised, it can result in mandibular fracture. As is known, biopsy or surgical excision of this lesion can result in severe hemorrhage, leading even to death. Therefore, accurate clinical and radiographic diagnosis is essential before starting any surgical intervention.

Exact evaluation of panoramic radiographs by dentists is important for the detection of silent lesions. With early detection of these lesions, many side effects can be prevented. On the other hand, sometimes peripheral lesions, such as peripheral hemangiomas, affect adjacent bone in a way that mimics a central lesion and are difficult to distinguish using only two-dimensional images such as panoramic radiographs. Therefore, using complementary imaging techniques such as CB

Hemangiomas are the most common tumors of infancy and infantile hemangiomas are the most common vascular tumors. The etiology of this tumor is unknown. Hemangiomas commonly occur in the skin followed by the deep tissues (intramuscular) and rarely within bones.

Hereby, the case of a 6-month-old girl whose whole left lower limb from thigh to ankle was involved with Hemangioma is reported. She had thrombocytopenia in lab data and abnormal coagulations profile. Biopsy was performed and treatment started base on diagnosis (Hemangioma). One month later, the swelling mildly decreased and platelet count raised.

Small hemangiomas do not need any treatment and are resolved spontaneously. However, gross or complicated hemangiomas need medical or surgical treatment. Propranolol, systemic glucocorticoids, vincristine and interferon alfa are alternative agents for medical treatment. Finally, surgical techniques, such as resection or amputation of limb, may still be the mainstay of treatment for lesions that do not respond.