جستجوی مقالات مرتبط با کلیدواژه « herbal remedy » در نشریات گروه « پزشکی »

Ulcerative colitis (UC) is a chronic, idiopathic, and recurrent disease with unknown etiology. Achillea wilhelmsii has been introduced as a herbal remedy for gastrointestinal ulcers and UC in traditional Persian medicine.

We examined the effectiveness of A. wilhelmsii aqueous extract against acetic-acid-induced UC in rats. Settings and Design: Fifty-six male Wister albino rats weighing 180–200 g were randomly divided into eight groups and after induction of UC were treated with five doses of aqueous extract of A. wilhelmsii.

After induction of UC by acetic acid, the aerial parts of A. wilhelmsii (6.25, 12.5, 25, 50, and 100mg/kg) were administered orally. On 11th day, the animals were euthanized by overdose of ether inhalation and the intestinal tissue was rapidly dissected for macroscopic, histological, and microscopic scores. Statistical Analysis Used: Data were analyzed by stats Directver.2.7.9 (SAS, Cary, North Carolina). One-way analysis of variance (ANOVA) followed by Newman–Keul’s post hoc test for multiple comparisons. A value of P < 0.05 was considered as significant level. Results were expressed as mean ± standard error of the mean (SEM).

All doses of A. wilhelmsii extract significantly reduced macroscopic and microscopic scores of colitis without significant changes in bodyweight of animals.

Treatment of the rats with A. wilhelmsii extract improved UC via its anti-inflammatory, antioxidant, and antimicrobial activities. According to the results of this study, A. wilhelmsii has a therapeutic effect against acetic-acid-induced UC in the animal model.

Jaundice is recognized by increased bilirubin level of blood and yellow appearance in skin, sclera and mucous membrane. Natural products have been used for treatment of jaundice for a long time and Persian Medicine can be a good source of natural drugs for this purpose. This study was done to find the materia medica used for jaundice based on Persian medicine (PM) texts including The Canon of Medicine (al-qanun), Al Hawi Fi Al Tibb, Tuhfat al-Mu’minin, Hedayat al-Motealemin fi Tibb, Zakhireye Khwarazmshahi, Al-Abniah 'an Haqaeq al-Adwia, Makhzan ul-Adwia and Ikhtiyarat Badie. One hundred eleven materia medica belonging to 51 families were identified as herbal remedies for treating jaundice. Apiaceae, Asteraceae, Cucurbitaceae, Fabaceae, Lamiaceae, Rosaceae and Zingiberaceae were the most dominant families. The results of this study may be present sources for pharmacological studies and development of new herbal medicines for jaundice. Asparagus, echium, arnebia, chicory, citron and purgative manna could be good candidate Materia Medica for future studies.

TNowadays, male infertility is one of the most common issues in the medical field and the main reason for it is impaired sperm production. Assisted Reproductive Techniques (ARTs) used for treatment of infertile couples are too costly. Currently, using herbal medicine due to lower side effects and cost has gained special significance. In this study, the effect of combination of several plants was evaluated on male infertility and pregnancy rate.
In this clinical trial, 40 infertile men referring to Alzahra hospital were randomly selected to take a combination of 7 plants including Allium cepa, Zingiber officinale, Ocimum basilicum, Cinnamomum verum, Citrus sinensis’ peel, Citrullus lanatus’seeds and Daucus carota’ seeds in a form of 700 mg capsule, once daily for 6 months. Before and after treatment, the patients’ blood and semen samples were collected and analyzed.
The number of sperms (P = 0.001), overall motility (P = 0.002), forward movement (P = 0.002), and normal morphology of sperms (P = 0.006) after treatment showed significant improvement. Also patients’ blood glucose levels meaningfully reduced after treatment (P = 0.036). The total volume of semen, total cholesterol, testosterone, and LH levels did not significantly differ with use of the compound herbal medicine. Seven couples during the study and after six months of receiving medication got pregnant.
Consumption of compound herbal medicine with the lowest risk and cost, significantly improves sperm parameters. It seems that the mechanism of action is through counteracting the effects of oxidative stress.