جستجوی مقالات مرتبط با کلیدواژه "herbal therapy" در نشریات گروه "پزشکی"

Several studies have recently been conducted on herbal plants due to their growing medicinal usage. Since it is estimated that male partner causes 40% of infertility, we aimed to examine the effects of herbal combinations, including Zayesh Booalidaroo + Safoof-e Hefz + Royal jelly, in increasing male fertility in men with oligoasthenoteratozoospermia (OAT).

A total of 50 OAT men were chosen, confirmed, and diagnosed by a urologist. They were randomly divided into two groups: Herbal and routine therapy (Sperigen supplement). All the parameters in semen analysis, hormonal assay, sperm DNA fragmentation, protamine deficiency, and the concentration of seminal plasma antioxidants, including malondialdehyde (MDA), total antioxidant capacity (TAC), and superoxide dismutase (SOD), were assessed in both groups before and after the intervention.

According to the obtained data, the herbal group showed improved total sperm and /mL count (P=0.0001 and P=0.007, respectively) along with increased progressive and total motility (P=0.02 and P=0.043, respectively), while routine therapy did not change any of sperm parameters significantly (P>0.05). Also, in hormonal assessment, there were no significant changes after interventions except in the herbal therapy group, where patients showed an elevated testosterone hormone level (P=0.00). Furthermore, the seminal concentration of all assessed antioxidant enzymes significantly increased in both groups (P≤0.05).

The antioxidant properties of herbal composition ingredients and their ability to improve the level of testosterone hormone are the main factors responsible for lessening the percentage of sperm DNA fragmentation and sperm parameters. So, this herbal therapy can be regarded as a practical option in improving semen quality.

 The increase in antimicrobial resistance has necessitated the screening of medicinal plants as potential agents for the treatment of microbial infections. The aim of the research was to explore antimicrobial activities of identified local plants, namely: Kigelia africana, Maytenus chasei, Ximenia caffra, and Schrebera alata.

 The powdered leaves of the selected plants were extracted using ethanol, hexane, ethyl acetate, methanol, and water as solvents, and phytochemical contents were determined. DPPH (1,1-diphenyl-2-picrylhydrazyl) assay was used to determine the antioxidant activities of the extracts. Plant extracts were tested against bacterial ATCC strains for their antimicrobial properties.

 Hexane and water extracts of K. africana showed the highest percentage yield (16.15% and 8.85%, respectively). The highest phenolic content was found in water extracts of S. alata (14.07 ± 4.8 mg/g) and ethanol extracts of M. chasei (8.6 ± 1.53 mg/g), while the highest flavonoid content was found in the ethyl acetate extract of M. chasei (997.34 ± 52.04 mg/g). For all the tested plant extracts, the ethanol extract of M. chasei showed the best IC50 value of ± 4.71 µg/mL against DPPH compared to other plant extracts. The water extracts of all the tested plants also showed high antioxidant activities. Extracts of X. caffra and S. alata showed comparable inhibitions to ciprofloxacin (P>0.05) against all tested organisms.

 The findings of the study suggest that the compounds in the plant extracts contained both antioxidant and antibacterial activities and these plants might be considered for the treatment of bacterial infections.

Periodontitis is a type of prevalent chronicinflammatory disorder resulting in a failure in the function oftissues supporting the tooth, like gingiva, alveolar bone, andperiodontal ligament. Although antibiotic therapy is a commontherapy for periodontitis cases, this approach can cause someadverse effects in these patients. Thus, finding an effectivecurative option with low side effects is still a puzzle.

This narrative review was conducted onthe effects of herbal and nano-based herbal medicine againstperiodontitis by searching different databases such as GoogleScholar, PubMed, Scopus, Web of Science, Science Direct, andScientific Information Databases.

According to published studies, some popular herbalformulations, such as Aloe vera, curcumin, Melaleuca alternifolia,and Scutellaria baicalensis Georgi, can be effective in periodontitistreatment. However, these herbal products may be accompaniedby some pharmacological limitations, such as poor bioavailability,instability, and weak water solubility. On the other hand,harnessing nano-based herbal formulations can elevate thebioavailability, diminish toxicity, and omit repeated administrationof drugs.

Herbal and nano-based herbal products can create agood chance to treat periodontitis efficiently.

  Depression has become an epidemic disorder in the world, which according to the World Health Organization is the first debilitating factor in the world. There are different approaches to its treatment, including the use of complementary medicine and herbal medicines. In recent years, there have been reports about the protective role of tea consumption in reducing the risk of depression, especially in the elderly. This study aimed to determine the effect of tea consumption on depression by reviewing quality published studies in this regard.

 To conduct a comprehensive review on the topic of tea and depression between 2005 and 2024, we used various search engines such as Persian language scientific resources SID and Magiran, as well as Google Scholar, Web of Science, PubMed, and Scopus. The search was conducted using the keywords "tea" and "depression" in combination.

 Out of 215 articles that were reviewed, the final analysis was conducted on 22 of them. Among these, 20 articles validated the correlation between tea consumption and a decrease in symptoms of depression. In most of these studies, it was highlighted that consuming at least three cups of tea daily had a positive impact.

 The results of this study have verified the advantages of drinking over 3 cups of green tea per day. It is recommended to consume green tea in various groups, especially in populations with a high incidence of depression, such as the elderly living in boarding centers.

Herbal medicine has been used as tea, ointment, capsules, syrup, whole herbs, and tablets to treat fertility disorders. The herbs and their treatment use in different localities vary, and the effectiveness of herbal treatment for routine treatment of diseases is still a debated issue to date. This study is a 20-year review of the herbal medicines treatment options for female fertility disorders to provide an updated publication of herbal treatments for female infertility and their associated outcomes, informing further research or translation.

PubMed, Google Scholar, Web of Science, Science Direct, and Cochrane databases were searched for clinical trials using Medical Subject Headings (MeSH) terms and related keywords, which retrieved 336 studies. All cross-sectional studies, reviews, and controlled trials utilizing phytotherapy on study participants without evidence of female infertility were excluded. Only 23 studies published in the English Language between January 2002 and August 2021 were included in the evidence synthesis after article screening.

Several herbal treatments in women cause a significant reduction in the symptoms of primary dysmenorrhea, PCOS, endometriosis, luteal phase defect, and vulvovaginal candidiasis, with substantial improvements in pregnancy and live birth rates. The herbal drugs identified from available studies were formulations – tablets or creams - with specified doses and administered orally or intravaginally.

Evidence exists that herbal treatments effectively treat female fertility disorders. However, they have not fully established the extent of safety, side effects, and pharmacological mechanisms of the therapeutic effects attributed to these herbal treatments.

Medicinal plants have revealed much attention as an alternative or complementary treatment for opioid withdrawal syndrome. The current review collects all available literature to verify the efficiency of herbal remedies in the management of symptoms associated with opioid withdrawal.

A systematic literature search was conducted from January 1990 to May 2021 on four bibliographic databases (Scopus, PubMed, Embase, and Web of Science) using the search terms “medicinal plant”, “withdrawal syndrome”, “opioid”, and all their equivalents. All randomized controlled trials (RCTs), published in the English language were included for data synthesis. The search was performed according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA). The Cochrane risk of bias tool was used to verify the quality of the included clinical trials.

A total of 12 RCTs were collected and used for data synthesis. The results of these studies indicated that herbal medicines were effective in treating opioid withdrawal syndrome and could alleviate the withdrawal symptoms, such as abdominal constrictions, diarrhea, bone pain, perspiration, and insomnia, when compared to conventional medications such as buprenorphine, clonidine, and methadone. However, more than 30% of RCTs were found to be at high risk of bias in the areas of selection, performance, detection, attrition, and reporting.

Although several RCTs have proven that herbal remedies are effective in reducing opioid withdrawal symptoms, the findings need to be viewed more carefully. Further RCTs with more participants, longer duration, and less risk of bias are needed in the claimed cases.

Osteoarthritis (OA) of the knee is one of the important medical complications in elderly peoples. Various pharmacological and non-pharmacological therapies are described for treatment of knee OA, but considerable side effects especially in old populations are the limiting factors. Traditional, complementary and integrative medicines have a long history in treatment of chronic diseases such as OA. Many different oral and topical drugs have been introduced for curing of OA in Persian medicine (PM) as one of the most important and historical systems of medicine. The aim of this survey was to review the clinical trials related to pharmacological treatment of knee OA with medicinal methods of PM. The main databases including PubMed, Scopus and ISI Web of Knowledge were searched and consequently eight clinical trials were achieved. Some of common dosage forms such as gel and oil and some of traditional ones like “Marham” and “Dohn” were used for treatment of OA in these studies. The investigated plants were suppressors for different pathways of inflammatory responses. Antioxidant capacity and analgesic effects were other recognized effects for some of these herbs. In clinical aspect, seven of eight papers that were presented in this study, showed a significant effect in the treatment of OA; however, more researches are required to judge these traditional therapies. eatinine and urea as compared to the untreated diabetic mice. Multipledoses of GTAE and G10 significantly (p≤0.05) decreased the volume and length of renal structures, compared to the diabetic untreated group.

According to the obtained results, GTAE groups can regulate the levels of biochemical parameters and inhibit kidney damages in alloxan induced diabetic mice. It appears that GTAE can be suggested for treatment of diabetes as an anti-diabetic supplement or drug.

Hot flashes are considered to be a common experience for menopausal women and they can compromise the quality of life. The objective of this study is to assess the efficacy of Cimicifuga racemosa in comparison with evening primrose oil (EPO) in postmenopausal women with menopause‑related symptoms.

This study was performed on 80 postmenopausal women with hot flashes. The participants were randomly divided into two groups by blocked randomization. The participants of one group received black cohosh and the other group received EPO for 8 weeks. The severity and number of hot flashes and quality of life were measured by four‑point scale, and the Menopause‑Specific Quality of Life (MENQOL) questionnaire at pre‑intervention, 1st, 4th, and 8th weeks after treatment. Data were analyzed in SPSS Version 16 using independent t‑test, Chi‑square, and Fisher’s exact test.

Average severity of hot flashes in both groups and number of hot flashes in black cohosh group in 8th week were significantly lower than 1st week (P < 0.001), but number of hot flashes in primrose oil group in 8th week showed no significant differences (P = 0.32). The number of hot flashes and quality of life score in black cohosh arm compared to EPO showed a significant decrease in the 8th week (P < 0.05). All MENQOL scores were significantly improved in two groups (P < 0.05), but the percentage of improvement in black cohosh arm was significantly superior to EPO group.

Both herbs were effective in reduction of severity of hot flashes and improvement of the quality of life, but it seems that black cohosh is more effective than primrose oil because it was able to reduce the number of hot flashes too.