جستجوی مقالات مرتبط با کلیدواژه "hpv infection" در نشریات گروه "پزشکی"
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Background
Human papillomavirus (HPV) is the most prevalent sexually transmitted infection, especially among sexually active individuals.
ObjectivesThis study aimed to determine the prevalence of HPV infection among males and females in Southern Iran. Although previous studies have explored HPV prevalence in various provinces across Iran, this research is unique as the first to examine a four-type sample within this region.
MethodsThis cross-sectional study involved a sample of residents from Southern Iran, comprising 82 females (71.9%) and 32 males (28.1%), aged between 13 and 74 years, most of whom were sexually active. The main focus of the research was to investigate HPV infection across various anatomical sites in both healthy women and those with external genital warts (eGW).
ResultsThe anatomical sites assessed included the oral, anal, vaginal, and urinary areas. Out of the total sample, 79 individuals (69.3%) tested positive for HPV. Within this group, 65 individuals (81.3%) were from the eGW group, while 14 individuals (41.2%) belonged to the normal population. A statistically significant difference (P ≤ 0.1) was observed in the prevalence of HPV in oral samples between the two groups. In the eGW group, 61 participants were positive for low-risk HPV (LR-HPV) genotypes, and 4 tested positive for HPV-18. Among the normal population, 14 individuals tested positive for LR-HPV genotypes. Notably, a higher proportion of positive HPV results—approximately 29%—was identified in anal and urinary samples compared to vaginal samples from females in the normal population.
ConclusionsSignificant differences in HPV prevalence were noted between individuals with eGW and those in the normal population. Overall, the prevalence of HPV among eGW individuals was approximately twice that of the normal population across the four anatomical sites. Further research is warranted to better understand the association between HPV infection, eGW, and various sociodemographic factors.
Keywords: External Genital Wart, Genotype, Prevalence, HPV Infection -
Background
Oral papilloma is benign lesion while there is concern about high-risk types of Human Papilloma Virus (HPV) for cancer.
Case PresentationThe patient was a 30-year-old woman who presented to the School of Dentistry, Semnan University of Medical Sciences for orthodontic treatment. Intraoral examinations revealed a prominent white papule on the tip of the tongue. Histopathologic exanimation revealed the proliferation of hyper keratinized stratified squamous epithelium arranged in projections with fibrovascular connective tissue cores, cell irregularity with hyperchromatic nucleus and koilocytes within the epithelium which confirmed the diagnosis of squamous papilloma (SP) with mild to moderate dysplasia. The patient was instructed to take care of the sexual behaviors and the injection of Gardasil vaccine was recommended. A month later, there was no evidence of a lesion.
ConclusionThough SPs are common lesions in the oral cavity, occurrence of dysplasia on SPs on the anterior part of the mouth is rare. Surgical removal supplemented by administration of Gardasil vaccine can be the treatment of choice in these cases. The significance of close attention to the oral lesions and consultation with an Oral and Maxillofacial Medicine Specialist is highly recommended in order to accurate diagnosis and timely treatment.
Keywords: Papilloma, Oral Cancer, Tongue Cancer, HPV Infection -
International Journal of Community Based Nursing and Midwifery, Volume:9 Issue: 2, Apr 2021, PP 92 -105Background
Human papillomavirus (HPV) is the most globally-prevalent sexually-transmitteddisease. Many stresses experienced by the patients after their disease is diagnosed affect the diseaseprogression, and these problems and consequences demonstrate the importance of the support for thepatients. The present research was conducted to explore the perception and experience of support inpatients diagnosed with HPV.
MethodsIn this qualitative study, 24 participants (17 patients, 2 spouses of these patients, and 5health service providers), selected using purposeful and snowballing sampling from April 2019 toMarch 2020, underwent an inductive content analysis conducted in dermatology clinic of ShahidFaghihi hospital, Shiraz, Iran. The data were collected through in-depth semi-structured interviews,all of which were recorded and transcribed. The data were analyzed in MAXQDA 2018 until datasaturation was reached.
ResultsThe patients aged 19-50 years old were married in 14 of the cases and their majority had genitalor anal warts. Their level of education ranged from junior high school to an MSc degree. Perceivedsupportive paradox emerged as the main theme which consisted of 2 categories of supportiveness andlack of support.
ConclusionThe present findings showed many challenges for the patients in the face of contradictorybehaviors by their relatives and health service providers. Integrated systems are required to develop inorder to promote the understanding of health service providers of HPV and counsel the patients to takeappropriate strategies and, therefore, eliminate their confusion and reduce their anxiety.
Keywords: HPV Infection, Qualitative research, Social Network, Support -
International Journal of Women’s Health and Reproduction Sciences, Volume:6 Issue: 1, Winter 2018, PP 2 -5As a unique preventable cancer, invasive cervical carcinoma is the second most common cancer among the women in developing countries. Change in womens lifestyle, worldwide spread of HPV infection and womens lack of effective education and screening programs in less developed countries constitute the most important factors for its high incidence and mortality rate. From a diagnostic perspective, atrophic smears may be interpreted as positive malignant smears in postmenopausal and occasionally in premenopausal women. However, rarely a high grade or malignant smear might be rendered as the atrophic smear. For this reason acquaintance with atrophic smears and their diagnostic challenges should be included in pathology and cytotechnology training courses. In this review, usual pattern of atrophic smears and differential diagnosis of atrophic smears along with mimics will be presented for decision making and particularly avoiding overdiagnosis.Keywords: Atrophic Pap smear, Invasive cervical cancer, HPV infection
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مقدمهویروس پاپیلومای انسانی یکی از شایع ترین عفونت های منتقل شونده از راه جنسی در سراسر جهان و علت اصلی سرطان دهانه رحم، در بین زنان 44-15 ساله است. از آنجایی که شناخت عوامل مرتبط با HPV در پیشگیری از این عفونت و به تبع آن سرطان سرویکس می تواند مفید باشد، لذا مطالعه حاضر با هدف بررسی بروز زگیل تناسلی و برخی عوامل مرتبط با آن در زنان مراجعه کننده به مرکز آموزشی و درمانی الزهراء تبریز انجام شد.روش کاراین مطالعه مقطعی در سال 93-1392 بر روی 221 زن مراجعه کننده به درمانگاه زنان بیمارستان الزهراء تبریز با شکایت عفونت واژینال انجام شد. اطلاعات از طریق پرسشنامه های مشخصات فردی- اجتماعی و عوامل خطر و آگاهی در مورد عفونت HPV و چک لیست ثبت شکایات و علائم بالینی و بررسی کولپوسکوپیک (در مورد زنانی که سوزش و خارش های مقاوم به درمان و یا زگیلی در ناحیه تناسلی خود داشتند) جمع آوری شد. تجزیه و تحلیل داده ها با استفاده از نرم افزار آماری SPSS (نسخه 19) و آزمون های تی مستقل، کای دو و تحلیل رگرسیون لوجستیک یک و چند متغیره انجام شد. میزان pکمتر از 05/0 معنی دار در نظر گرفته شد.یافته هادر این مطالعه 46 نفر (8/20%) از افراد HPV اثبات شده توسط کولپوسکوپی و بیوپسی داشتند. از عوامل مورد بررسی، تنها بین طول مدت ازدواج (023/0=p) و داشتن همسر دوم توسط شوهر (039/0=p) با HPV ارتباط آماری معنی داری وجود داشت. میانگین نمره آگاهی 9/3±04/12 از محدوده نمره قابل دستیابی 0 تا 24 بود. بین افراد با HPV مثبت و منفی از نظر میزان آگاهی، اختلاف آماری معنی داری وجود نداشت (936/0=p). همچنین احتمال بروز HPV در افرادی که کمتر از 10 سال از ازدواجشان می گذشت، تقریبا دو برابر افرادی بود که بیش از 10 سال از ازدواجشان می گذشت.نتیجه گیریبا توجه به بروز بالای عفونت HPV در این مطالعه و آگاهی متوسط شرکت کنندگان نسبت به عفونت HPV ضرورت دارد که برنامه ای جامع در مورد ارتقای آگاهی کل افراد جامعه در معرض خطر مد نظر قرار گیرد.کلید واژگان: آگاهی, سرطان دهانه رحم, عفونت HPVIntroductionHuman Papilloma Virus (HPV) is one of the most common sexual transmitted infections worldwide; it is the main cause of cervical cancer in women aged 15-44 years. Since identifying the factors of HPV can be useful in prevention of this infection and cervical cancer, so this study was performed with aim to determine the incidence of Human Papilloma Virus infection and some relevant factors among women referring to Alzahra Therapeutic-Educational Center of Tabriz.MethodsThis cross-sectional study was conducted on 221 women aged 15-50 years with vaginal infection referred to Gynecology section of Alzahra hospital in Tabriz-Iran, 2013-2014. Data was collected using the questionnaires including socio-demographic characteristics, risk factors, knowledge about Human Papilloma Virus, and also the checklist of recording complaints, clinical symptoms and colposcopic evaluation (in the case of women who had treatment-refractory irritation and itching or warts in the genital area). Data were analyzed using SPSS software (version 19), and independent t-test, chi-square and single and multiple logistic regression model. PResultsIn this study, 46 patients (20.8%) had HPV confirmed by colposcopy and biopsy. Among the studied factors, only duration of marriage (P=0.023) and having second partner by husband (P=0.039) were significantly related to HPV. The mean of knowledge score was 12.04±3.9 from obtainable score of 0-20. There were no significant differences among the subjects with positive and negative HPV in terms of knowledge (P=0.936). Also, the incidence of HPV was two folds high in the women with marriage duration less than 10 years than the women with marriage duration more than 10 years.ConclusionRegarding to high incidence of HPV infection and moderate knowledge of participants about HPV infection in this research, it is essential to consider a comprehensive program to promote the knowledge of total high risk persons.Keywords: Cervical cancer, HPV infection, Knowledge
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