جستجوی مقالات مرتبط با کلیدواژه "hyposalivation" در نشریات گروه "پزشکی"

The potential association between asthma and various oral and dental conditions such as caries, tooth wear, periodontal diseases, and alterations in the oral mucosa remains a topic of ongoing debate among dental professionals. This study sought to assess the prevalence of hyposalivation and dry mouth in children aged 3 to 12 years with asthma, who were referred to Bu Ali Sina Hospital in Sari in 2023.

This descriptive-analytical epidemiological study was conducted on pediatric asthma patients at Bu Ali Sina Hospital in Sari. Data on each patient’s asthma severity, duration of the condition, and medication usage were collected through questionnaires and interviews with patients’ parents. Unstimulated salivary flow was measured using the gravimetric method. Statistical analyses were performed using Spearman's correlation coefficient, Mann-Whitney, Kruskal-Wallis, and Chi-square tests to compare the data, with a significance level set at 0.05.

A total of 66 children (32 boys and 34 girls) participated in this study. Hyposalivation was observed in 33.3% of the children (22 out of 66), while 42.4% (28 out of 66) experienced dry mouth. A statistically significant association was found between gender and hyposalivation, with boys being more affected than girls (P<0.05). Furthermore, dry mouth was notably more prevalent among children with hyposalivation (P<0.001). Children with hyposalivation were approximately 16 times more likely to report dry mouth compared to those without hyposalivation (Odds Ratio=16.35, P=0.001).

This study highlights the higher prevalence of hyposalivation in boys compared to girls, though no significant association was found between gender and presence of dry mouth. A strong, statistically significant link between hyposalivation and dry mouth was confirmed through multiple logistic regression analysis. These findings suggest that children with hyposalivation are at a markedly increased risk of experiencing dry mouth, underscoring the need for early detection and management in pediatric asthma patients.

This study investigated the relationship between oral health related quality of life and hyposalivation and dry mouth in patients with chronic renal failure (CRF) undergoing hemodialysis.

This descriptive-analytical study was conducted in 200 patients with CRF undergoing hemodialysis attending the dialysis department in Sari Imam Khomeini Hospital, 2021. Patients completed oral health-related quality of life questionnaires (OHIP-14) with additive and simple count assessment methods. To diagnose dry mouth, unstimulated saliva was collected and patients were asked nine questions, of which five positive answers indicated dry mouth. Data analysis was done in SPSS V18. Pearson's or Spearman's correlation coefficient were applied to investigate the association between quality of life score and unstimulated salivary flow, and t-test or Mann-Whitney test were used to compare the quality of life scores between the groups with and without dry mouth.

Hyposalivation was observed in 66 patients (33%). The OHIP-14 score was significantly higher in both additive and simple count methods in patients with dry mouth and hyposalivation (P<0.05). Comparing different variables, the findings showed that 66.7% of the patients with hyposalivation were older than 58 years of age (P=0.007). In addition, 60.6% of patients with dry mouth had diabetes (P=0.01).

Dry mouth and hyposalivation reduce the quality of life in patients with CRF undergoing hemodialysis. Also, dry mouth and hyposalivation were relatively common problems in these patients. The treatment of these problems is necessary because of their impact on patients' quality of life.

Rheumatoid arthritis is one of the most common chronic inflammatory diseases of the joints that has many effects on oral health. The aim of this study was to evaluate the quality of life (QOL) and oral health indicators in patients with rheumatoid arthritis and healthy subjects.

A case-control study was carried out in Sari Tooba Clinic, 2018-2019. Data of all participants (case group, n=24 and control group, n=24), including demographic data, smoke consumption, and wearing removable dentures were recorded and all participants responded to nine questions about oral dryness and other systemic diseases. The Oral Health Impact Profile-14 (OHIP-14) was used and patients were clinically examined. DMFT was calculated and plaque, gingival, and sulcus bleeding indices were determined on Ramfjord teeth. The flow rate of non-stimulated saliva was investigated using a weight estimation method. Quantitative variables were compared between the case group and control group applying independent T-test or its non-parametric equivalent (Mann-Whitney).

There were two men (8.3%) and 22 women (91.7%) in each group. The mean ages in the case and control groups were 45.62 ± 11.29 and 45.58 ± 10.57 years. The age and gender distribution was not significantly different between the two groups. The mean DMFT, plaque, gingival, and sulcus bleeding indices and non-stimulatory saliva flow rate were higher in case group than the control group, but only the plaque index in the case group (5.62±2.63) was significantly different from the control group (4±2.44) (P=0.026). GI, PI and SBI were found to be significantly associated with oral health-related QOL (P<0.05).

Examination, diagnosis, and treatment of oral health indicators is effective in improving the QOL in patients with rheumatoid arthritis.

The aim of this study was to determine the effect of xerostomia and hyposalivation on quality of life in patients receiving chemotherapy and evaluating unstimulated salivary flow rate in these patients.

This descriptive-analytic study was conducted in 80 cancer patients with xerostomia undergoing chemotherapy. The Health Impact Profile-14 (OHIP-14) was administered to evaluate the effect of xerostomia and hyposalivation on patients’ quality of life. Data analysis was done in SPSS V22.

The additive and simple count OHIP-14 scores were 20.66 and 3.10, respectively. Among 80 patients with xerostomia, 50 had hyposalivation (P<0.001).

Xerostomia and hyposalivation in patients undergoing chemotherapy have negative effects on oral health-related quality of life and these patients require more attention.