جستجوی مقالات مرتبط با کلیدواژه "iron-deficiency anemia" در نشریات گروه "پزشکی"

 This study was conducted to determine how the theory of planned behavior (TPB) can be applied as a theoretical framework for managing iron deficiency anemia among student girls.

 This quasi-experimental study was conducted in descriptive and interventional phases on student girls residing in Fariman, Iran. In the descriptive phase, 200 students were selected by multi-stage random sampling. In the intervention phase, 80 students were randomly divided into experimental and control groups. Data were collected using two questionnaires. One questionnaire included questions about demographic variables, and the other was a TPB construct questionnaire. The educational program was held based on the TPB model for the intervention group in four sessions. The intervention was evaluated immediately and three months after the training session. The data were analyzed by SPSS 20 using repeated measures, ANOVA, t-tests, and linear correlation.

 In this study, the research sample consisted of 200 student girls with a mean age of 13.11±0.5. Before the intervention, there was no statistically significant difference in the average preventive nutrition behavior score between the two groups (P>0.05). However, after the education in the intervention group, the subjective norm score and perceived behavioral control increased from 8.19±0.98 to 8.88±1.2 and from 18.1±3.6 to 19.8±3.3, respectively. In addition, intention and preventive behavior increased from 14.6±2 to 16.05±1.9 and from 24.8±4.5 to 26.9±4.1, respectively. These differences were found to be statistically significant (P>0.05).

 The results of this study demonstrated that educational interventions based on the TPB model can be effective in promoting preventive behaviors for anemia.

Thalassemia is an inherited blood disorder with a defect in the sufficient production of a protein called hemoglobin. We aimed to investigate the simple blood indices of patients with Beta Thalassemia Trait (BTT) and Iron Deficiency Anemia (IDA) to propose a new formula using logistic regression for differentiate two characteristics from each other.

Among the 702 records of the BTT Counseling Center (Khoy, Iran-2022), 292 cases (219 iron deficiency anemia (IDA) and 73 BTT) were eligible for the study. Blood indices such as RBC, HGB, HbA2 described and used to diagnose two types of participants. Blood indices had high multicollinearity that was modified. Logistic regression for blood indices fitted and goodness of fit indices with Area Under ROC curve (AUC) estimated.

The average age of the participants was 24.56 yr. The status of Multicollinearity between independent variables was modified. The HGB, MCV, HbA2, and HbA variables were used in the model and only HbA2 status was significant (P<0.001). According to the output of the model, for each unit increase in HbA2, the chance of having BTT was about 8.5 times higher than IDA. The sensitivity, specificity, AUC curve, and accuracy of the final model were estimated to be 97, 72, 84, and 93%, respectively. A regression formula to differentiate BTT from IDA proposed.

In studies related to the differentiation of the BTT from IDA, the presence of the HbA2 index in the model and prediction is very necessary.

Rational utilization of parenteral iron with meticulous calculated doses will promote appropriate utilization of healthcare resources. The aim is to study utilization of intravenous Iron Sucrose at patient level and hospital level. 

This prospective-observational study was conducted over 6 months. Case-records of 125 indoor patients were reviewed for intravenous (IV) Iron Sucrose prescription and patient details and treatment details for patients were procured. 

125 patient records were divided in (Antenatal care and Non Antenatal care) ANC and Non ANC groups; and their Mean age was 36(S.D ± 16) years. IV Iron Sucrose was prescribed the most in anemic pregnant patients 41(32.8%) followed by severely debilitated patients on other injectable drugs 37(6%). The Total administered dose was more than the Standard calculated dose in an alarming 84(67.2%) of the patients. Utilisation of IV iron sucrose in Defined Daily Dose per 100 bed days (DDD/100 bed days) was found to be 0.42 in total patients whereas it was 0.59 in ANC and 0.36 in Non ANC groups. 

This research highlighted that overutilization and administering more than the required dose of IV iron sucrose, could be effectively tackled by calculation of its standard dose by Ganzoni’s formula. Studying the monthly trends and comparing utilization of parenteral iron with the help of DDD/100 bed days by hospitals can help in comparing utilization and also assist for budgetary preparedness of hospitals. There is also a dire need to formulate universally accepted guidelines for the use of parenteral iron in general adult population.

Iron Deficiency Anemia (IDA) is a massive health concern with a high frequency in Iran. Differentiating between IDA and other microcytic-hypochromic anemia like beta thalassemia minor requires demanding and money consuming tests. That is why this study aimed to assess well-suited and conclusive deferential indexes for IDA diagnosis among children aged between 1-15 years old

Blood samples were collected from outpatients aged between 1-15 years old. Consequently, Ferritin, Hemoglobin, Serum Iron, RBC count, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell volume distribution width (RDW), total iron binding capacity (TIBC) were determined. Furthermore, differential indexes including Mentzer, Shine and Lal and England-Frazer were measured and the data were analyzed using SPSS.

Out of 100 children, 72 individuals were healthy and 28 had IDA. The average age was 3.6±2.9 years. The prediction value of the RBC indexes for the differentiation IDA were as follows: MCV (99%), HB (96%), Ferritin (95%), HCT (87%), MCH (79%), Serum Iron (71%), RBC count (51%), RDW (27%), and TIBC (26%). The prediction values of the formulas were as follows: Shine and Lal (96%), Mentzer (80%), and England-Frazer (79%).

According to the findings, it is possible to diagnose IDA by Complete Blood Count (CBC) test accompanied by differential indexes. A simple selective index such as Shine and Lal might be very beneficial for screening of IDA. This index is also useful for the diagnosis of microcytic anemia.

A high level of hemoglobin at birth is one of the iron reserves needed by infants to deal with iron deficiency anemia. This study aimed to assess the iron status in neonates born by cesarean section and the effect of maternal characteristics and other laboratory measures on neonatal iron levels. Moreover, it was designed to investigate anemia and identify its factors. This descriptive correlational study was conducted in 2022 on 50 neonates by caesarean section in Babylon Hospital, Iraq. Serum ferritin and other laboratory parameters from neonatal umbilical cord blood were measured in addition to others that had been recorded for both neonates and their mothers. The data were analyzed using the t-test. Out of 50 neonates, 8 infants had low serum ferritin levels and 4 of these 8 had anemia, and 6 of them were born to mothers from rural areas. The mean maternal age of neonates with low serum ferritin was significantly higher than those with normal or high serum ferritin. The results showed that the place of residence and its clean climate and healthy nutrition can have a direct effect on the ferritin level. No significant effect of serum ferritin on WBC, reticulocytes, and platelet counts was observed in this study. Anemia is significantly associated with low serum ferritin neonates; in addition, maternal age and residence have significant effects on neonatal serum ferritin. Considering the high prevalence of iron deficiency anemia in mothers and even in mothers with proper nutrition, iron deficiency in the mother leads to a decrease in the baby's reserves and makes him susceptible to iron deficiency in the first months after birth. The importance of using iron supplements during pregnancy becomes clearer, and one should not be satisfied only with diet. Due to the adverse effects of increasing the number of pregnancies on the mother's iron reserves, appropriate spacing should be observed.

Iron deficiency anemia (IDA) is one of the major health issues in the world, especially in developing countries. During adolescence, iron deficiency can be caused by a growth spurt, inadequate nutritional intake, parasite infection, and heavy blood loss during menstruation. Regarding the importance of this issue, we aimed to assess the iron profile in adolescent scavengers living in slum areas.

This was a cross-sectional study conducted in October 2016 at an alternative school for adolescents working as scavengers in Bekasi, Indonesia. Data on menstrual status, weight and height measurements, and blood samples were collected to define iron status (iron depletion, iron deficiency, and IDA).

In this study, 96 adolescents aged 10–18 years were recruited. The prevalence of anemia was 13.6%, and half was caused by iron deficiency. The iron profiles of subjects were iron depletion (2.1%), iron deficiency (18.8%), and IDA (7.3%). Hemoglobin, ferritin, and transferrin saturation were significantly lower in females (P<0.01, P=0.01, P<0.01 respectively).

Anemia, iron depletion, iron deficiency, and IDA are more prevalent among adolescent girls. Special attention is needed to improve the iron status of girls, especially by giving iron supplementation for IDA prevention. Moreover, achieving the optimal iron reserve is imperative to enter a safe and healthy pregnancy by reducing delivery complications due to inadequate iron storage of both mother and fetus.

 
We aimed to evaluate serum and salivary vitamin B12 levels in patients with iron deficiency anemia (IDA) with and without recurring aphthous ulcers (RAS).

 
Study participants were divided into three groups, clinically healthy control group (n = 25), an IDA patient with RAS (n = 25), and an IDA without RAS (n = 25). The enzyme-linked immunosorbent assay (ELISA) method was used to assess the serum and salivary B-12 levels blindly. Data analyses were performed using one-way ANOVA and the Tukey’s post hoc test using R software.

 
There were statistically significant differences regarding serum and salivary B12 levels among study groups (P<0.001). All pairwise comparisons showed significant differences regarding serum (P<0.001) and salivary (P ≤ 0.002) B12 levels.

 
The Control group (396 ± 18.2 pg/mL) was within the normal serum level of vitamin B12 (200-900 pg/mL), while in IDA with RAS (111 ± 15.4 pg/mL) and IDA without RAS (145 ± 57.2 pg/mL) serum level of vitamin B12 is lower than the normal range and significantly lower than the control group.

Micronutrients are one of the major groups of nutrients required by the body. Vitamins and minerals are considered micronutrients that are vital for growth, immune function, brain development, and many other important functions. they also play a role in preventing and fighting diseases. Malnutrition (undernutrition) is caused by a lack of nutrients and is the leading cause of death in the world. Biofortification of staple crops with micronutrients has been proposed as a potential technique for combating malnutrition by enriching target food crops. Iron deficiency is one of the most frequent dietary problems worldwide, affecting both industrialized and developing nations. Iron deficiency anemia is a condition in which the blood doesn’t have enough healthy red blood cells. It may be due to blood loss, lack of red blood cell production, and high rates of red blood cell destruction, but it leads to reduced oxygen flow to the body’s organs and causes fatigue, skin pallor, shortness of breath, light-headedness, dizziness, or a fast heartbeat. Nanotechnology is the creation and use of innovative structures, materials, and systems in a variety of disciplines, including agriculture, food, and medicine. The study and management of matter at sizes of 1 to 100 nanometers is known as nanotechnology. It can help with everything from food production to manufacturing, and it can make a big impact on food quality and safety, and also the health benefits of foods. While nanotechnology may be the greatest technique to reduce anemia’s effects while also boosting iron bioavailability in the blood, it has some negative effect on the body that depends on the duration of exposure and the level of intake. In this paper, we discuss how micronutrient deficiencies and anemia can be prevented by using nano techniques as well as how they impact the human body.

Iron deficiency anemia in children or women in pregnancy, is a public health problem in some countries. The World Health Organization (WHO) has called on all countries to achieve a 5% reduction in anemia in women of childbearing age, including adolescent girls, by 2025. One of the programs is iron supplementation. The success depends on the adherence of adolescent girls to consume iron tablets. This systematic review aimed to find the level of compliance to iron supplementation consumption among adolescent girls and explore barriers and facilitator factors to such adherence.

This article was a systematic review and conducted a multi-database search. The articles passed the PRISMA flow diagram process. The inclusion and exclusion rules decided the qualification of studies included. Of 1066 articles, we obtained 20 studies for the systematic review.

The lowest compliance found were 26.2% and 26.3%, and was high (>80%) in intervention studies involving supervision and monitoring and peer educator. All articles' barrier and facilitator factors were classified into four categories; personal, social, environmental, and regimen.

Efforts to improve adolescent compliance to take iron tablets should consider all of these factors.

Chronic heart failure (CHF) patients are usually faced with reduced physical function, inappropriate sport tolerance and inability for daily activities. Studies showed that increasing serum hemoglobin (Hb) level in CHF can increase the maximum oxygen delivery and the consequent functional capacity. We aimed to assess this finding.

This single-arm clinical trial study was conducted on patients with CHF between March 2019 and 2020 in our hospital. In baseline, NYHA function class and 6-minute walking test (6MWT) were recorded. Persian standard version of health-related quality of life (Iranian-QoL) questionnaire and visual analogue scale (VAS) for fatigue were also administered to patients. After calculating the required dose of elemental iron, intravenous ferric carboxymaltose solution was infused in 1000 mg dosage for patients with hemoglobin level of more than 11 mg/dl (anemia) and in 500 mg dosage for patients with hemoglobin level of more than 14 mg/dl (without anemia). All the examinations were repeated after 12 weeks.

Eventually, 50 (20 male and 30 female) patients with a mean age of 58.88 ± 17.05 years underwent analysis. The mean distance in 6MWT was significantly increased from baseline (mean±SD change: 17±6m, p < 0.001). In addition, the mean fatigue and quality of life scores were significantly improved 12 weeks after treatment in comparison to the baseline (P<0.001).

a one-cycle treatment with intravenous ferric carboxymaltose can efficiently improve the functional capacity and quality of life in patients with chronic heart failure who suffer from iron deficiency, with and without anemia.

 To our knowledge in our country not many studies have been done regarding the iron status and cognitive function in children. Therefore, the aim of this study was to investigate the relationship between serum iron levels and cognitive function in children aged 1 month to 5 years in our institution.

 This study was conducted for 18 months in the pediatric population of a tertiary care hospital in Mysore, India, after obtaining approval from the Ethics Committee of the institution. A total of 255 subjects aged between 1 month and 5 years were selected as per the eligibility criteria. From these children, a venous blood sample was sent for determination of iron levels and total iron binding capacity. Cognitive abilities were assessed using the age-appropriate Ages and Stages Questionnaire (ASQ -3).

 The mean age of the study population was 22.87±14.83 months and the male-to-female ratio was 1.7:1. Totally, 230 out of 255 children were iron deficient (90.2%), 91.3% boys and 88.3 % girls. Anemia was found in 55.7% of the children, with 94.3% of those with anemia suffering from ID. ID was found to have a negative significant effect on fine motor skills (p < 0.0001) and problem-solving ability (p=0.01). Gross motor skills were significantly impaired by ID (p<0.0001).

 This study re-emphasizes that ID and IDA have a negative impact on cognitive development and performance, with more severe effects in the last stage of ID –IDA.

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a significant health and financial issue in the current century. Despite significant attempts to manage the illness, the transmission routes of the virus and its widespread genomic mutations have led to an increasing number of new infections and mortality rates. In the absence of specific treatment for this new virus, identifying and managing factors affecting the prognosis of the disease is one of the critical strategies to reduce disease mortality. Patients with iron deficiency anemia (IDA), who account for an estimated half a billion people globally, are more prone to infections due to immune system disorders. Since they visit hospitals more frequently for follow-up care and diagnosis, they are more susceptible to becoming infected with SARS-CoV-2. Once infected with SARS-CoV-2, low hemoglobin (Hb) levels and compromised immune systems disrupt the restriction of infection in these individuals, ultimately leading to severe complications of COVID-19.

to evaluate the frequency of iron deficiency with or without anemia among hemophilia patients with its correlation with other factors including age, address, type and severity of hemophilia. Study design: Cross sectional study, it was conducted at Babylon hereditary blood disease center at Babylon Government/Iraq. For a period of 10 months, from 1st of February to end of November 2019. The study included 60 patients of hemophilia classified into: hemophilia A (40) patients and hemophilia B (20) patients; all of them were males; age ranged from 6 months to 15 years. All patients were sent for white blood cells count, Hb, Red blood cells indices, serum ferritin level, ESR, C-reactive protein and virology screening. The study reveals IDA occurred in 28.3% and 58.3% of patients developed ID. There was more declined in mean ferritin level among patients with IDA reached 3.7 ± 1.4 ng ml-1 , compared  to 5.7± 1.4 ng ml-1 in ID and in those with sever deficiency. Higher percentage of ID and IDA occurred in complicated hemophilia and those were lived in rural areas. Iron deficiency and IDA are common among hemophilia patients.