جستجوی مقالات مرتبط با کلیدواژه « laboratory tests » در نشریات گروه « پزشکی »

 Clinical, radiological, and laboratory findings characteristic of the coronavirus disease 2019 (COVID-19) infection have already been investigated and identified; however, data on pregnant women infected with COVID-19 are limited. This study aims to examine the clinical, radiological, and laboratory characteristics of pregnant women compared to non-pregnant women with COVID-19 disease. 

 This hospital-based retrospective age-matched case-control study included two groups, pregnant and non-pregnant women, each consisting of 51 patients hospitalized with COVID-19 in Bushehr, Iran.  Demographic, clinical, and laboratory information was extracted from medical records using a predefined checklist. 

 Except for cough, there were no statistically significant differences in clinical signs and symptoms between pregnant and non-pregnant women. Although hemoglobin oxygen saturations are statistically significant among the two groups, this difference is not clinically significant (95% vs 93%). There were no statistically significant differences between pregnant and non-pregnant women in the pattern of pulmonary involvement in chest CT findings. Laboratory factors such as serum hemoglobin, red blood cell count, absolute lymphocyte count, prothrombin time and partial thromboplastin time, serum creatinine, serum potassium, and lactate dehydrogenase had statistically significant differences between the two groups. However, these differences were not clinically significant. 

 In a few aspects, the clinical characteristics and laboratory test results of COVID-19 in pregnant patients seem to be distinctive from their nonpregnant controls. We believe our findings can guide the prenatal and postnatal considerations for COVID-19 pregnant patients.

The etiology of polyneuropathies varies in the pediatric population, where hereditary or metabolic disorders are far more common than in adults. However, treatable polyneuropathies, also prevalent in these settings, are those to prioritize. Moreover, diagnosing subacute and chronic symptoms in children can be challenging compared to adults. Therefore, selecting the best and most relevant laboratory investigations and paraclinical studies is critical. This taskcan be relatively challenging in countries with limited resources or insurance coverage. This study describe the various types of polyneuropathies found in children and their characteristics and suggest an algorithm for using the best laboratory tests in the context of the Iranian healthcare system.

 Tramadol is a unique opioid and the most prescribed opioid worldwide. Tramadol-related overdose and death have been increased in several countries. Due to the high level of tramadol use, misuse, and overdose in Iran, and considering the cost and time spent doing laboratory tests for all patients, this study aimed to investigate the possible relationship between changes in laboratory findings of patients poisoned by tramadol and their neurological manifestations to evaluate the need for these tests.

 This was a cross-sectional descriptive study of patients with acute tramadol poisoning who were referred to the Emergency department of Sina hospital, Tabriz, Iran from March 2020 to March 2021. Lab tests taken from the patient in the emergency department were recorded. Meanwhile, the patients’ neurological symptoms were noted. And demographic information of patients was collected in a predesigned checklist and was analyzed by IBM® SPSS® 20.0 release software.

 A total of 95 patients including 76.8% male and 23.2% female with an average age of 28.26±10.57 were admitted to the emergency department. The most common symptoms of neurological impairment experienced by patients were seizure (32.6%) and decreased level of consciousness (38.8%). There was no relationship between the neurological symptoms of tramadol poisoning with neither arterial blood gas characteristics nor hematological factors (P>0.05).

 The neurological manifestations of tramadol poisoning were not related to arterial blood gas characteristics such as PH, PCO2, PO2, and HCO3−. Also, there was no relationship between hematological factors including white blood cell (WBC), red cell distribution width (RDW), platelets (Plt), sodium (Na), potassium (K) and blood sugar (BS), and neurological symptoms caused by acute tramadol poisoning. Therefore, requesting these tests during tramadol poisoning should be reconsidered.

 COVID-19 has enforced high burden on health systems universally. To better allocate limited health equipment, we aimed to investigate the prognostic impacts of laboratory parameters.

 All SARS-CoV-2 patients admitted to Imam-Reza University Hospital, Mashhad, Iran, during three COVID19 peak periods in Iran (March to April 2020, July to August, and October to November 2020) were enrolled the study. Demographic and laboratory data were extracted and compared between survivors and non-survivors. Regression analyses and receiver operating characteristic (ROC curve) were used to identify risk factors and assess the ability of laboratory tests in predicting in-hospital mortality.

 A total of 2156 COVID19 patients were included in the analysis, with a mean age of 60.20 (±18.8) years. Most patients were male (57%). Multiple regression analysis identified older age (OR=1.01), male sex (OR=2.34), lymphopenia (OR=2.12), LDH >500U/L (OR=2.17), hypernatremia (OR=9.7), urea >45mg/dL (OR=3.6), and BS >200mg/dl (OR=1.93) as significant risk factors for in-hospital death. Using ROC curve analysis, D-dimer (>1000ng/ml) as well as CK-Mb (>28U/L) both with sensitivities and specificities of more than 80% and PPV of about 90% were able to identify patients with higher possibility of in-hospital death.

 Male sex, older age, lymphopenia, hypernatremia, increased Urea, increased LDH, and hyperglycemia may serve as potential risk factors for in-hospital death. D-dimer and CK-MB may be used in identifying patients with high probability of in-hospital death. These tests may be used in clinical decision-making in order to improve outcomes of patients with COVID-19.

Laboratory analysis errors in procedure or interpretation may be seen during the process of completing physician test orders. They may also result in rejection of the requests due to some applicability reasons. Hence, this study was carried out to determine the rate and reasons for such rejections in clinical settings.

This cross-sectional comparative study was performed on 104008 laboratory tests in a one-year period in terms of the percentage and type of errors that occurred in Shahid Bahonar Hospital in Kerman, Iran, in 2018. The types of studied errors included hemolysis, sample clotting, insufficient sample size, and mistakes in labels or absence of labels on the sample.

In this study, 104008 laboratory tests were performed, with 2299 (2.21%) sample rejections, 456 (32.31%) complete blood count (CBC) sample clotting; 417 (29.38 %) hemolysis; and 150 (17.47 %) inadequate sample volume as the majority of errors. There was no statistically significant relationship between pre-analysis errors and clinical aspects (P=0.124).

According to the results, it may be concluded that considering the high prevalence of laboratory errors in comparison with the majority of other studies, continuous training courses and determination of the causes of these errors are crucial to attaining better function and basic knowledge.

Context: Findings have been perceived that only fewer children face COVID-19 and among infected, they have fewer violent signs. Being less severity among children could be significant for meditating therapeutics for high-risk adults and the elderly. Evidence Acquisition: This study reviewed the main associated symptoms related to COVID-19 such as epidemiologic, laboratory-related, and therapeutic aspects among pediatric patients. In this narrative review, the most recent reproduced data on pediatric patients’ clinical revelation with COVID-19 have been considered and reviewed.

All ages of pediatric patients were susceptible against the COVID-19. There wasn’t any significant sex difference. Asymptomatic, mild, or moderate signs were reported in more than 90% of all patients. Although pediatric patients clinical appearance of COVID-19 was commonly less severe compare to adult patients, young pediatric patients, exclusively infants, were vulnerable to infection.

It is important that clinicians must be informed of possible clinical manifestations of pediatric patients ’COVID-19 cases to avoid neglecting or overdiagnosis of patients. As well as, this review provided strong documents of human-to-human transmission.

 Dengue fever is caused by any one of four types of dengue viruses (DEN1-DEN4), spread mainly by Aedes aegypti. India had the largest number of dengue cases, with about 33 million apparent and another 100 million asymptomatic infections occurring annually. The patients typically present with the sudden onset of fever, frontal headache, retroorbital pain. The laboratory diagnosis can be made by IgM ELISA or by NS1 antigen-detection ELISA during the acute phase. This research was conducted from January 2018 to December 2018 at Sir T. hospital and Government Medical College in Bhavnagar, Gujarat. The patients having complaints of fever, headache, myalgia, arthralgia or rash, were clinically examined, and laboratory investigated for dengue with NS1 and/or IgM dengue antibody. A total of 536 patients was screened, of which 112 patients were diagnosed as dengue fever at 21% dengue positivity rate, based on detection of NS1 (46/304, 15%), and anti-dengue IgM (66/232, 28%) in their sera. The majority of the patients were males (77/112, 69%). The majority of patients were in 11–30 years’ age group (66/316, 21%). Fever (100%) was the chief presenting complaint, followed by headache (83, 93%), and myalgia (79, 89%). The highest number (28) of dengue patients was observed in the month of October 2018. According to this study results, the physicians in the dengue-endemic area should be aware of dengue in acute febrile illnesses and use the appropriate laboratory tests such as NS1 antigen and IgM antibodies for early dengue diagnosis. This can help clinicians to prevent morbidity and mortality associated with dengue.