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عضویت

جستجوی مقالات مرتبط با کلیدواژه « mediastinitis » در نشریات گروه « پزشکی »

  • Saviz Pejhan, Ehsan Sadeghian, Kambiz Sheikhi, Farahnaz Sadegh Beigy, Fezzeh Elyasinia, Reza Eslamian*, Ali Reza Mirsharifi
    Background

    Mediastinitis is a significant complication of open heart surgery and other thoracic operations. Deep sternal wound complications notably increase morbidity and mortality. The optimal treatment for deep sternal wounds following sternotomy remains a topic of discussion. Options such as repeated irrigation and debridement of the wound, closed chest catheter irrigation, and recent plastic surgery approaches like pectoralis major flap transposition all have their proponents.

    Methods

    Given the high prevalence of Deep Sternal Wound Infection (DSWI), we conducted this retrospective descriptive study. We used existing information to compare the conservative method of repeated irrigation and debridement with pectoralis major flap transposition. We presented the results using descriptive and analytic methods. We evaluated a total of 125 patient health records with deep sternal wound infection over a ten-year period (2003-2013).

    Results

    The results of this study showed that 83.2% of patients who developed DSWI after surgery suffered from underlying diseases such as diabetes, renal failure, etc. However, no relationship was found between the presence of an underlying disease and recovery. Furthermore, no significant relationship was observed between diabetes and recovery. Among the 125 assessed files, 50 patients received a pectoralis flap, among which 48 patients recovered with sternal stabilization and only 2 patients recovered without stabilization. Conversely, among cases without pectoralis flapping, records were available for only 67 patients, of whom only 35 patients recovered with sternal stabilization while 32 patients recovered without sternal stabilization. Recovery was significantly enhanced in the group receiving flapping.

    Conclusions

    The only factor that improved the outcome in our assessment was the use of pectoralis flapping. This is consistent with the results of studies published in recent years that used plastic surgery methods, i.e., pectorals muscle or omentum flapping, which are associated with a high success rate and reduced length of inpatient stay.

    Keywords: Mediastinitis, Median Sternotomy, Pectoralis Flapping}
  • پریسا فیروزبخش، شیوا خالق پرست، سعیده مظلوم زاده، پردیس مرادنژاد*
    هدف

    این مطالعه با هدف مرور پژوهش هایی که به بررسی مداخلات موثر در پیشگیری از وقوع عفونت زخم متعاقب جراحی قلب باز پرداخته اند انجام شد.

    زمینه

    عفونت زخم محل جراحی قفسه سینه و عفونت های عمقی زخم استرنوم از عوارض جدی هستند که شیوع آن حدود 0/4 تا 5 درصد است و می توانند به واسطه طولانی کردن مدت بستری، نیاز به جراحی های مکرر یا آنتی بیوتیک های طولانی مدت، بار مالی زیادی را به بیمار و سیستم سلامت تحمیل کنند. بر اساس مطالعات، عوامل خطر متعددی برای بروز عفونت زخم محل جراحی قفسه سینه  شناسایی شده است که بسیاری از آنها قابل کنترل هستند و با شناسایی و مدیریت مناسب، می توان تا حد زیادی از بروز این عارضه جدی و خطرناک پیشگیری کرد.

    روش کار

    این مطالعه مروری در سال 1401 با جستجوی پایگاه های داده ای شامل SID، Scopus، Uptodate، Medline، PubMed، Science Direct، و Magiran با استفاده از کلیدواژه های پیشگیری، مدیاستینیت، جراحی قفسه سینه و معادل انگلیسی آنها انجام شد. مقالات اصیل که گزارش پژوهش ها با طراحی مقطعی، مورد شاهدی، کوهورت، یا کارآزمایی بالینی را به زبان فارسی یا انگلیسی در بازه زمانی سال های 2000 تا 2021 میلادی در نشریات نمایه شده در پایگاه های داده ای مورد جستجو منتشر کرده بودند و دسترسی به متن کامل آنها مقدور بود مورد بررسی قرار گرفتند. معیارهای خروج از مطالعه شامل مقالات مروری، نامه به سردبیر، و گزارش مورد بود. پس از جستجوی اولیه، 62 مقاله مرتبط یافت شد که در آخر، با توجه به معیارهای ورود و خروج، تعداد 16 مورد از آنها به طور کامل مورد بررسی قرار گرفتند.

    یافته ها

      از جمله اقدامات قبل از انجام جراحی برای پیشگیری از بروز عفونت زخم محل جراحی قفسه سینه می توان به رعایت بهداشت دست، کاهش وزن، ترک سیگار، کنترل مناسب قند خون قبل وحین و بعد از عمل جراحی، تجویز آنتی بیوتیک پروفیلاکتیک مناسب، دکلونیزاسیون بینی و حلق از استاف اوریوس با استفاده از پماد موپیروسین، و رفع موهای زاید با استفاده از کرم موبر (بدون تیغ) اشاره نمود. ضدعفونی کردن فیلد جراحی با استفاده از کلرهگزیدین، استفاده از روش های مناسب جراحی برای بستن زخم و حفظ ثبات و پایداری استرنوم، و آموزش مناسب بیماران توسط پرستاران درباره علایم هشدار، و پیگیری دقیق آنها از جمله اقداماتی هستند که می توانند در حین عمل و پس از آن به پیشگیری از بروز عفونت زخم محل جراحی قفسه سینه کمک قابل توجهی کنند.

    نتیجه گیری:

     با شناسایی عوامل خطر زخم محل جراحی قفسه سینه و کنترل دقیق و به موقع آن می توان تا حد زیادی از بروز عارضه جدی و تهدیدکننده زندگی زخم عفونت زخم محل جراحی قفسه سینه پیشگیری نمود.

    کلید واژگان: عفونت زخم محل جراحی قفسه سینه, عفونت عمقی زخم استرنوم, جراحی قلب, پیشگیری}
    Parisa Firoozbakhsh, Shiva Khaleghparast Athari, Saiedeh Mazloomzadeh, Pardis Moradnejad*
    Aim

    The aim of this article is to review studies that have evaluated effective interventions in the prevention of mediastinitis following cardiothoracic surgery.

    Background

    Mediastinitis and deep surgical wound infections (DSWI) are life-threatening complications of median sternotomy and have a prevalence of 0.4-5 percent. They can produce a significant financial burden on the patient and also the health care system by prolonging the hospitalization period and the need for repeated surgeries or long-term antibiotics. Several risk factors have been identified for mediastinitis following cardiothoracic surgery, many of which are easily preventable by proper diagnosis.

    Method

    . In this literature review, databases including PubMed, Medline, UpToDate, Scopus, Science Direct, SID, and Magiran were searched out using the keywords Mediastinitis, Prevention, Cardiothoracic surgery, and their Persian equivalents. Persian and English original articles (including cross-sectional, case- control, cohort studies, and clinical trials) investigating the effective interventions in the prevention of me- diastinitis following cardiothoracic surgeries and were published between 2000 and 2021 and had an available full text, were included in the current study; review articles, letter to editors, and case reports published in non-authoritative journals were excluded from this study. After primary search, 62 relevant articles were found and based on inclusion/exclusion criteria, 16 articles were finally selected and reviewed in the cur- rent study.

    Findings

    Mediastinitis ca n be prevented before surgery by hand hygiene, weight loss, smoking cessa-tion, proper prophylactic antibiotics, decolonization of nasopharynx and oropharynx from Staph aureus by Mupirocin ointment, and removing hair using depilatory cream (not the blade). Tight blood glucose monitoring before, after, and during the surgery, disinfection of the surgical field by chlorhexidine, using a proper surgical technique for wound closure and stabilizing the sternum, and proper patient training by nurses about red flags of infection can play an important role in the prevention of mediastinitis.

    Conclusion

      Mediastinitis ca n be easily prevented by identifying its risk factors and controlling them accurately and in a timely manner.

    Keywords: Mediastinitis, Deep surgical wound infection (DSWI), Thoracic surgery, prevention}
  • Mohsen Ziyaeifard, Rasoul Azarfarin, Seyed Mostafa Alavi, Evaz Heydarpur, MohammadHassan Ghaffarinejad, Fatemehshima Hadipourzadeh *, Shahin Salabaty
    Background

    Mediastinitis is a severe complication after cardiac surgery. The aim of this study was to determine the incidence of postoperative mediastinitis, the predictors of mediastinitis, and sternal dehiscence in adult cardiac surgery patients.

    Methods

    In this retrospective study, the records of 60 patients were evaluated regarding mediastinitis and dehiscence after cardiac surgery in a referral cardiovascular hospital in Tehran, Iran.

    Results

    In the present study, 4360 patients underwent surgery over 18 months from September 2017 through March 2019. Of this total, 60 patients with a diagnosis of mediastinitis and sternal dehiscence were included in the study’s analysis. In our investigation, 1.03% of the cases (45/4360) had mediastinitis and 0.3% (15/4360) cases experienced sternal dehiscence. Among the many risk factors that were examined, there were significant differences between the mediastinitis and dehiscence groups regarding diabetes mellitus (P =0.007), a history of preoperative chronic kidney disease (P =0.02), a history of myocardial infarction (P =0.002), a history of arrhythmia before cardiac surgery (P =0.02), reoperation due to postoperative bleeding (P =0.07), the number of patients transferred to the ICU with the sternum left open (P <0.001), postoperative pulmonary complications (P =0.007), and postoperative arrhythmias (P =0.04).

    Conclusions

    There were significant differences between the mediastinitis and dehiscence groups regarding diabetes mellitus, a history of preoperative chronic kidney disease, myocardial infarction and arrhythmias before cardiac surgery, reoperation due to postoperative bleeding, the number of patients transferred to the ICU with the sternum left open, postoperative pulmonary complications, and postoperative arrhythmias. (Iranian Heart Journal 2021; 22(3): 6-12)

    Keywords: MEDIASTINITIS, Dehiscence, Cardiac Surgery, risk factors}
  • Behdad Gharib, Masoud Mohammadpour, Meisam Sharifzadeh, Fatemeh Mirashrafi, Bahareh Yaghmaie, Neda Pak, Mehrzad Mehdizadeh, Hamid Eshaghi, Mojtaba Gorji, Sara Memarian
    Parapharyngeal abscess is a life-threatening disease. Upper respiratory tract infection is the main cause in children. We present a 15-month-old boy admitted to the emergency ward with the chief complaint of difficulty in breathing caused by parapharyngealabscess. His condition deteriorated gradually, and he transferred to the operation theater quickly for abscess drainage and because of the difficulty in orotracheal intubation; a tracheostomy was performed. His respiratory condition deteriorated 2 days after PICU admission, and the medical team noticed an unexplainable respiratory distress. A chest x ray obtained and showed a right side pneumothorax and subcutaneous emphysema around theneck area. The case presented here, had not been diagnosed at the first examination; however, there were enough clinical clues (such as respiratory distress, drooling, torticollis, bulging of theneck, previous viral respiratory infection, possible pharyngeal trauma). The story of this case reminds us the importance of the precise physical exam and history taking which could be life-saving.
    Keywords: Parapharyngeal abscess, Respiratory distress, Mediastinitis, Retropharyngeal abscess}
  • Ebrahim Razi*, Abdolhossein Davoodabadi, Armin Razi
    Spontaneous esophageal perforation or Boerhaave''s syndrome is an uncommon condition that may occur following forceful vomiting and lead to mediastinitis. It is associated with high mortality and morbidity in absence of therapy. We present a case of spontaneous esophageal perforation in a 63 year-old man who developed a right-sided effusion, an unusual presentation. This case report and the relevant literature reveal that delay in prompt surgical repair is associated with a high morbidity and mortality.
    Keywords: Esophageal perforation, Mediastinitis, Pleural effusion}
  • Samer Kassem, Tommaso Generali, Andrea Daprati, Federico Martinelli, Alessandro Parolari
    Introduction

    A 43-year-old man developed a mediastinal abscess after a redo aortic valve along with an ascending aorta replacement and also a sub-aortic membrane resection. He was surgically revised: as there were no signs of involvement of the valve and vascular prosthesis, a pedunculated tract of the greater omentum was mobilized and positioned around the aortic prosthesis. During a 10-month follow-up, it has been revealed that the patient is doing well and has no recurrence of the infection. Use of the great omentum could be considered in the selected mediastinitis cases.

    Case Presentation

    A 43-year-old man was referred to our institution for a severe aortic regurgitation and an ascending aorta enlargement associated with a relapsing sub-aortic membrane, which had been treated in his childhood. He underwent a redo ascending aorta replacement and an aortic valve replacement (mechanical prosthesis) along with a resection of the relapsing sub-valvular membrane. Some weeks after he was admitted to another hospital for fever, arthromyalgias and chest pain. After a few days, he developed an inflammatory jugular swelling and underwent a chest CT scan showing a bulky anterior mediastinal abscess in the direct continuity with the sternum. A further chest CT scan showed a mediastinal para-aortic capsulated mass, 135 × 85 × 90 mm in dimension, well delimited over the surrounding plans. At the top of the lesion, a further fluid collection was appreciated, extending through the sternum over the subcutaneous tissues, 30 × 20 mm in dimension. Re-sternotomy was performed and the mediastinal mass was opened and drained. After an extension of the median sternotomy through the epigastrium, a pedunculated tract of the greater omentum was mobilized and positioned around the vascular prosthesis to fill the empty space left by the abscess.

    Conclusions

    The greater omentum is well known in cardiothoracic surgery for its valuable features such as plasticity, immune competence, good blood supply and neovascularization-potential. Dead space can be obliterated by omental flap because of its plasticity qualities. It contains a large number of immunologically active cells likely to be responsible for its anti-infective properties. We can affirm that use of the great omentum could be considered in selected post-operative mediastinitis cases after cardiac surgery.

    Keywords: Mediastinitis, Omental Flap, Mediastinal Abscess}
  • Rezayat Parvizi, Mojtaba Varshochi, Sohrab Negargar, Susan Hassanzadeh
    Purulent mediastinitis is an unusual complication of median sternotomy. This complication often occurs shortly, usually within two weeks, after surgery. This study has been planned to clarify the situation of life-threatening infectious complications after surgical operations at our center and to better the ways of prevention as much as possible.
    In this study, all the patients who had undergone median sternotomy were observed over a 4-year period. The documentation of the diagnoses was completed, information about the patients including demographic characteristics, type of surgery, pre-, intra- and postoperative risk factors, clinical and laboratory findings, etiological diagnoses, responsible organisms, management methods and finally the outcome of the patients were collected and analyzed by a statistical software (SPSS-Win).
    1.2, and 15% needed preoperative intra aortic balloon pump. The mortality rate was 31%.
    This complication is distinguished by its clinical manifestations and positive culturing from the mediastinum. Microbial etiology is influenced by the source of contamination and must be recognized for any center separately. A combination of antimicrobial therapy and surgical intervention has better results. A better evaluation of the patients’ preoperative conditions, promotion of surgical techniques and preventive measures, and an early diagnosis of mediastinitis will be effective in the reduction of this
    complication
    Keywords: mediastinitis, open heart surgery}
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