جستجوی مقالات مرتبط با کلیدواژه "metronidazole (mtn)" در نشریات گروه "پزشکی"

Background and Antibiotics have worldwide uses and they can enter water sources through different ways. Due to their different inappropriate effects, they have created a major concern in environmental control practices. Metronidazole (MTN) is an example of these antibiotics. This study was performed to investigate the efficiency of ozonation process (SOP) in MTN removal from aqueous solutions. The solution pH (3-12), reaction time and initial MTN concentration (1-40 mg/L) were investigated for their effects on efficiency of the removal process. The MTN concentration was analyzed by HPLC. Biodegradability improvement and mineralization rate were studied by BOD5/COD and TOC tests, respectively. The optimum pH for SOP was 10. The best compatibility for drug degradation kinetic was found with pseudo-second order (liner type II) model. The BOD5/COD increased from 0.09 in SOP influent to 0.33 in SOP effluent and the MTN mineralization rate was about 68%. Higher ozone decomposition in alkaline pH increased the radical production and improved removal efficiency. Moreover, higher mineralization rate reduced the environmental risks of effluent discharges.

Pharmaceutical products، particularly antibiotics، due to their cumulative and inappropriate effects and creating drug resistances، as inevitably pollutants، have been created a major concern in environmental control. Metronidazole (MTN) is one of these antibiotics. Hence، the aim of this study was investigation of MTN removal efficiency by catalytic ozonation process (COP) in presence of produced magnesium oxide nanocrystals as catalyst. The influences of several operational factors for their effects on removal were evaluated، including solution pH (3-12)، reaction time، MgO dosage (0. 25-4 g/L) and initial MTN concentration (1-40 mg/L). Also degradation kinetic، biodegradability improvement and mineralization rate were studied for the COP. For degradation kinetic the best compatibility was with pseudo-second order (liner type II) model. The optimum pH and MgO dosage for COP were determined to be 10 and 0. 25 g/L، respectively. Under optimum condition the complete removal of 40 mg/L MTN solution was observed after 20 min. The results illustrate that MgO nanocrystals markedly accelerated the MTN degradation in and the COP significantly increased BOD5/COD ratio and caused 94% MTN mineralization.