جستجوی مقالات مرتبط با کلیدواژه "mullerian agenesis" در نشریات گروه "پزشکی"

Uterine anomalies have been caused by impairment in the formation, evolution, or defect in the connection of Mullerian bud during the embryonic period. In this study, a case of unicornuate uterus with cervical agenesis is presented.

The patient was a 14-year female with symptoms of backache, pain in the left thigh, nausea, vomiting, and chill, which were started six months ago (no complain of abdominal pain). Sonography was performed and a cystic appendage with a thick wall containing internal eco and somewhat septa solid components appeared in the sinistral pelvis, indicating the sinistral rudimentary horn of the uterus with hematometra (secondary to cervical agenesis). Sonography showed a 32×92 mm twist tubular cystic appendage having an internal eco in left lower quadrant, indicating hydrosalpinx. No left ovary tissue was observed. Hymen was checked and it was imperforate. Due to cervical agenesis, blind vagina and hydrosalpanx, hysterectomy and left salpingectomy surgeries were performed. The pathological answer showed cervical  agenesis and  a unicornuate uterus containing hematometra and hematosalpinx in the left fallopian tube and endometrioma cyst.

Gynecologic problems should be considered in adolescents with initial amenorrhea and abdominal pain.

Unicornate uterus is one of the congenital uterus abnormalities in several forms. In this article, we report a rare case of unicornate uterus with non-communicated rudimentary horn and active endometrium combined with the unilateral ovarian endometrioma undistinguished of it.
A 21 years old woman with acute abdominal pain and pelvic mass referred to Imam Reza hospital, Mashhad in 2015. Ultrasonography reported a bicornate uterus and a large cystic mass with size of 12.5×17.5 cm in the right ovary. CBC and tumour markers were normal, only CA-125 was increased. The patient was operated because of the acute abdomen. In the explanatory laparotomy and hysteroscopy, a unicornate uterus with right accessory corn combined to the right ovary was showed that they formed a unique cystic mass contained a chocolate liquid. Rudimentary horn accompanied by the right ovary and falopan tube were resected. Histopathological report confirmed simultaneous endometrioma of the right ovary and hematometra in the rudimentary horn.
Unicornate uterus with non-communicated rudimentary horn and active endometrium may be associated with hematometra and/or endometrioma. The accumulation of chocolate like fluid may lead to destroy of ovary tissue and elimination of rudimentary horn coincide with oophorectomy seemed unavoidable. Therefore, early diagnosis and removal of rudimentary horn can avoid of complication such as endometriosis, oophorectomy and ectopic pregnancy.