جستجوی مقالات مرتبط با کلیدواژه « mushroom poisoning » در نشریات گروه « پزشکی »

Mushroom poisoning is a major health condition with a wide range of clinical and paraclinical features. This study aimed at evaluating the frequency of clinical and paraclinical manifestations of mushroom poisoning in patients referred to Shahid Rahimi Hospital in Khorramabad, Iran, over a one-year period (2018-2019).

The data collected were associated with the clinical manifestations, age, sex, seasons, type of mushrooms, patients’ residence, latent phase, clinical and laboratory findings, length of hospital stay, interventions and the treatments. The underlying diseases were also recorded. After data collection, they were entered into SPSS, version 18 software and analyzed statistically.

124 patients with a mean age of 36.65 years old were recruited into the study, 73 of whom were male and 51 female. The mean duration of the hospital stay was 2.19 days. The mean time elapsed between the consumption and the symptoms development was 4.42 hours. Similarly, the duration between the consumption and referral to the hospital was 4.72 hours. Most cases occurred in the Spring (91.1%). The most common clinical signs in the poisoned subjects were nausea and vomiting (81.5%). The most therapeutic medications were Livergol (48.4%) and Atropin (33.1%), and most subjects had consumed mushrooms grown in the nature (79.8%). One person died because of the poisoning (0.8%).

A large majority of the patients developed nausea and vomiting, whom were treated with drugs, but one patient died. People should be aware of, warned againt, and educated about the types of mushrooms before consumption.

In Spring 2018, due to intense rainfalls in Iran, plenty of mushrooms had grown, some of which were poisonous and their consumption had induced poisoning in people of different provinces; 1151 mushroom poisoning cases were reported within 25 days from 12 May to 9 July 2018.

This study aimed to address this issue from the public health perspective. The study further aimed at reporting the mortality and morbidity associated with mushroom poisoning and ascertaining the reasons behind the increase in the numbers of the affected persons.

This report was based on the review of official reports and a field assessment in the areas affected bymushroom poisoning in the western part of Iran.

There were 1151 mushroom poisoning cases, out of which 1133 (98.4%) were hospitalized, and unfortunately, 18 (1.56%) died. Kermanshah province had the highest rate of mushroom poisoning casualties, out which seven people died. A total of 12 provinces were affected.

Lack of knowledge of local people about the types of mushroom and their inability to differentiate between the toxic and non-toxic mushrooms, as well as lack of a swift and convenient immediate warning system has caused this incident of massive mushroom poisoning. However, planning and proper management can help to resolve these problems.

Mushroom poisoning is a global problem and can be a source of major mortality and morbidity. Children can easily be exposed to inadvertent mushroom ingestion. The aim of this study was to assess the demographic, clinical, and laboratory features of pediatric patients with mushroom poisoning. This was a retrospective and observational study of reported cases of exposure to mushroom poisoning at the Department of Pediatrics at West China Second University Hospital of Sichuan University and Wan Yuan Central Hospital between June 2011 and July 2016. The patients’ demographic, clinical, and laboratory features were evaluated. Fifty-eight patients aged between 1.22 and 16.71 years old were studied; 24 patients were female (41%) and 34 were male (59%). Thirty-seven (63.79%) patients had consumed mushrooms in the summer. The most frequent complaints were nausea and vomiting (98.28%). The onset of mushroom toxicity symptoms was divided to early-onset (< 6 hours after ingestion) and late-onset groups (6 to 24 hours). The incidence of life-threatening cases was higher in the late-onset group than that of the early-onset group (88.9% versus 12.2%, P < 0.0001). Three patients with mushroom poisoning died due to fatal hepatic failure, and one patient died due to cardiac arrest (myocardial toxicity). The value of White Blood cell Count (WBC), total bilirubin, and number of involved organs were significantly higher in the group who died than that of the survived group (14.9 × 109 versus 11.8 × 109, P = 0.002; 125 versus 8.5, P = 0.0001; 4.5 versus 1, P < 0.0001, respectively). The level of hemoglobin was lower in the group who died than those who survived (111 versus 132, P = 0.001). Parents and children must be taught to avoid eating unknown mushrooms. Life-threatening poisoning cases are often encountered in patients with late-onset mushroom toxicity symptoms. When children present nausea and vomiting during the rainy season, doctors should maintain keen vigilance towards mushroom poisoning. Acute liver failure is the main cause of death, yet myocardial toxicity should also be considered.

From April 28 to May 28, 2018, more than 1200 patients with impression of mushroom poisoning were referred to hospital emergency departments in 13 west and northwestern provinces, Iran; 112 (8.9%) patients were hospitalized and 19 were expired (ie, a fatality rate of 1.5%). The outbreak began in Kermanshah province with increasing number of patients presenting with severe abdominal pain, nausea, vomiting, and diarrhea soon after consumption of wild mushrooms. Lepiota brunneioncarnata, Hypholoma fascicalare, and Coprinopsis atramentaria have been involved in this outbreak. To prevent similar outbreaks, raising public awareness about risky behaviors of collecting and consuming wild self-picked mushrooms is of paramount importance. Herein, we present our experience with this outbreak.

Besides their nutritional value, mushrooms have shown beneficial effects on human body organs; thus, people are interested in consumption of mushrooms regardless of their safety. In this report, we present patients with suspected mushroom poisoning, who were admitted to the Medical Toxicology Department of Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Seventeen mushroom-poisoned patients were admitted to our department from April 2012 to May 2015. Following the evaluation of the vital signs, biochemical analysis was done and in parallel, treatment was initiated based on the laboratory tests results and clinical manifestations. In this period, 17 mushroom-poisoned individuals (11 males (64.7%) and 6 females (35.3%) with mean age of 28.26±18.05 years old) were referred to our department. Subjects presenting the signs of intoxication within 6 hours post-ingestion comprised 58.8% of our patients. The rate of mortality was zero but 3 patients presented with some levels of unconsciousness. Only one patient had augmented levels of AST with no evidence of hepatic failure. Coagulopathy as reflected by increased INR was observed in 2 patients. Regarding the season in which the poisoning occurred, the majority of cases happened in spring and autumn. Similar to other reports on mushroom-poisoned patients, we observed gastrointestinal disturbances as the major symptom. Since the majority of mushroom poisoning cases occur following the ingestion of accidentally picked mushrooms, risk communication practices should be improved to increase the public awareness of mushrooms toxic effects

One of the highly toxic mushrooms that are common in the northwest region of Iran is Amanita phalloides, which might result in renal or liver failure. This is a case report of a patient referred a few days after consumption of wild mushrooms to emergency department having gastrointestinal complaint whose experiments indicated liver and renal failure. The supportive treatment was given to the patient prescribing N-acetyl cysteine (NAC) and Livergol (silymarin) along with hemodialysis. A few days after admission to the hospital, the patient died due to severe clinical symptoms. The patient was poisoned by A. phalloides complaining gastrointestinal symptoms including nausea; vomiting and watery diarrhea about six hours after consumption and then, amatoxin in the mushroom caused damage to hepatocytes and renal cells and finally led to hepatorenal failure. Deaths caused by this type of mushroom are extremely high and necessary trainings should be provided to the people by the health system not to consume wild mushrooms, especially in spring and summer.

Although the majority of mushroom ingestions are benign، some result in significant toxicity and death. Of greatest concern is the hepatotoxic amatoxin-containing mushroom، which may be fatal even small ingestions. Identification of amatoxin poisoning can prove to be difficult due to delay in onset of symptoms and difficulty with identification of mushrooms. Case Report: We present one case of mushroom ingestion in Kerman، province what according to clinical course and laboratory finding، we believe to be an amanita species، treated with multiple dose of activated charcoal، N-acetylcysteine، high-dose penicillin and liver Gol (silymarin). We present the successful treatment a patient who ingested hepato-toxicity induced mushrooms، further، this case is evidence of a mushroom variety responsible for toxicity never previously implicated in the southeastern Iran.

Mushroom poisoning as a medical emergency can be a challenging problem for physicians. Despite the vast resources of poisonous mushrooms in Iran, few studies have been done in this regard, especially in the southwest region of the Caspian Sea that is very suitable for mushroom growth. Therefore, the aim of this study was to evaluate our experience with mushroom poisoning in this region. This retrospective study reviewed the records of 102 patients who were admitted to the Emergency Department of Razi Hospital of Rasht, the only referral department in this region, from May 2006 to May 2011. Data were analyzed by Chi-square test, ANOVA, and student’s t-test. The patients’ age ranged from 13 to 75 years and 47 of them were male and the rest 55 were female. Overall, 57.8% of mushroom poisoning cases occurred in patients from urban areas. Most incidences were reported between September and October, the rainy season in Guilan. Except for four patients with tachycardia, others had stable vital signs. The most frequent symptoms (86.4%) were nausea and vomiting. Complete blood cell count revealed that 28.4% of the patients had leukocytosis but all of them had platelet counts of less than 100000. This study showed that all cases had mild to moderate symptoms that were treated by simple supportive therapies. This suggested that mushroom species in our region are less dangerous but further studies need to establish what toxins and species are responsible for mushroom toxicity.