جستجوی مقالات مرتبط با کلیدواژه « pain tolerance » در نشریات گروه « پزشکی »

Due to the painful and long-term treatments of cancer, children with cancer may suffer from severe psychological problems such as anxiety and decreased level of pain tolerance. Accordingly, psychological treatments such as play therapy can be helpful in this regard. The purpose of this study was to determine the effectiveness of cognitive-behavioral play therapy on pain tolerance and trait-state anxiety in children with cancer in Isfahan. The statistical population of this study was all children aged 9 to 12 years old who were referred to specialized cancer clinic of Isfahan in 2016. 30 of them were selected through purposeful sampling and randomly assigned into two groups of experimental and control. The results were analyzed using covariance analysis. The results of data analysis indicated that cognitive-behavioral therapy games resulted in increased pain tolerance and decreased trait anxiety in children with cancer (p <0.05). According to the findings of this study, cognitive-behavioral play therapy can be used as a complementary therapy to relieve anxiety and increase pain tolerance in these children. Declaration of Interest: None.

Hyperalgesia is a common clinical phenomenon among opioid dependent patients on methadone maintenance therapy (MMT) and it may be associated with undertreated pain and/or therapeutic failure. This study aimed to investigate association between serum methadone concentration (SMC) and cold pressor pain responses. Cold pressor pain responses in 147 opioid dependent patients on MMT were assessed using cold pressor test (CPT) at 0 hour and at 2, 4, 8, 12, and 24 hours after the dose intake. Blood samples were collected at 24 hours after the dose. Serum methadone concentrations were measured using the Methadone ELISA kit and classified into two categories: 0.05). Our results suggest an association of trough methadone concentration with the cold pressor pain threshold among opioid dependent patients on MMT. It would be useful to study the mechanisms underlying this association to help managing pain in such a population.