جستجوی مقالات مرتبط با کلیدواژه "predictive factor" در نشریات گروه "پزشکی"

Having a child with cerebral palsy (CP) is a stressful experience for the family specially mothers. Caring of this children take a lots of time and energy from family. The balance of life may be decreased by the influence of factors related to the child or mother. Therefore, the present study intended to investigate the predictive factors affecting the life balance of mothers with CP.

This study was a cross sectional descriptive-analytical research that conducted in Ahvaz in 2021. A total of 135 mothers (mean age= 33.37(7.93)) with at least one children under the age of ten CP participated in this research. Data were collected using life balance index, general health questionnaire, time management quality, and demographic information checklists. GMFCS E&R and MACS were used to determine the level of gross motor and manual ability function. To investigate the effect of predictor variables on the quantity of life balance, generalized univariate linear models were used.

Life Balance of mothers of children with CP was very unbalanced (45.2%) or unbalanced (35.6%). Based on regression coefficient of each variable, it was determined that MACS (B = 0.192), comorbidity in the children with CP (B= 0.187), gross motor function (B= 0.137), general health (B= 0.024) and maternal age (beta = 0.01), respectively, contributed the most in the prediction of life balance variances.

Life balance is a serious affected domain in mothers caring CP children. Child-related factors had a more effective role in predicting the life balance of mothers of CP children than mother-related factors.

 The aim of this study is to evaluate the factors affecting treatment success in patients who underwent Shock wave lithotripsy (SWL) for ureter stones and to investigate the effect of Storz Medical Lithotripsy Index (SMLI) on treatment effectiveness in ureteric stones.

 Prospective data were collected on patients undergoing SWL treatment for ureter stones between January 2013 and May 2021. Stone location, number, and size were determined with Non contrast CT (NCCT) for all patients. All patients underwent SWL with a Storz Modulith SLK lithotripsy machine with local anaesthesia. The total amount of energy applied to the stone was calculated using the Storz Medical Lithotripsy Index (SMLI). All patients were evaluated for stone-free status by X-ray at least 2 weeks after treatment. The success of the procedure was defined as the patient being completely stone free (SF) or detection of residual fragments < 4 mm that did not require further treatment

 A total of 1199 patients with ureter stones were included in the study. The mean age of the patients was 43.11 ± 10.65 (18-73), and the mean BMI was 27.87±8.12(19.02-38.65). During SWL, 89.3% of patients demonstrated excellent pain tolerance (1070/1199). A total of 119 patients could not tolerate pain during SWL (10.7%).Treatment success was associated with fewer treatment sessions (2.04±1.64 vs. 2.50 ± 1.48; p < 0.001), smaller stone size (7.35±2.99 vs. 9.02 ± 3.81; p < 0.001) and higher SMLI/stone size (29.70 ± 17.48 vs. 24.98±16.01; p < 0.001). In the univariate and multivariate regression analysis, the factors affecting the success of the treatment were the number of sessions (OR: 1.147), stone size (OR: 1.112), SMLI/stone size (OR: 1.115) and pain tolerance (OR: 0.740).

 In the treatment of ureteral stones with SWL, number of sessions, stone size, SMLI/stone size, and pain tolerance are the factors affecting success. SMLI per stone size is a statistically significant factor for predicting SWL success.

The aim of this study was to identify factors that can be used to predict severe neutropenia (grade 3 or higher) in patients with advanced urothelial cancer after cisplatin-based systemic chemotherapy.
The study examined 79 Korean patients with advanced urothelial cancer who were treated with several cycles of cisplatin-based systemic chemotherapy from May 2006 to May 2015. Risk factors for neutropenia (grade 3 or higher) and for the occurrence of neutropenia (grade 3 or higher) during the first cycle of chemotherapy were examined.
Thirty-six out of the 79 patients (45.6%) developed neutropenia at grade 3 or higher during the first cycle of cisplatin-based systemic chemotherapy: 18 (22.7%) of these experienced grade 3 neutropenia and 18 (22.7%) experienced grade 4. Multivariate analysis identified pretreatment neutrophil counts (P = .001) as the only significant factor predictive for severe neutropenia.
The pretreatment neutrophil count was found to be the factor that poses a significant and independent risk in development of severe neutropenia induced by applying cisplatin-based systemic chemotherapy to patients with advanced urothelial cancer.

So far, many studies investigated factors that affect pregnancy rates after intrauterine insemination (IUI). Various investigators have not agreed on the nature and ranking of these criteria.

The aim of this study was to assess the predictive factors for pregnancy rate after controlled ovarian hyperstimulation (COH)/ IUI.

Retrospective study of all patients undergoing IUI at Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital from January 2006 to December 2009. In total 980 IUI cycles in 569 couples were analyzed. All women in the study underwent ovarian stimulation using gonadotropin and IUI was performed 36 h after triggering ovulation. The primary outcome measure was clinical pregnancy rates. Predictive factors evaluated were female age, body mass index (BMI), duration of infertility, type of infertility, follicle stimulating hormone (FSH) level and estradiol (E2) on third day of the cycle, number of preovulatory follicles, endometrial thichness, total motil sperm (TMS) count, and ratio of progressive motile sperm.

The overall clinical pregnancy rate was 4.7%. Among the predictive factors after multivariate logistic regression analysis level of BMI (<25 kg/m²), number of preovulatory follicles (≥2), level of FSH (<9.4 IU/L), level of E2 (<80 pg/ml) and the ratio of progressive motile sperm (>50%) significantly influenced the clinical pregnancy rate.

Level of BMI, FSH, estradiol, number of preovulatory follicles and the ratio of progressive motile sperm may determine IUI procedure as optimum treatment model.

Ingestion of caustic substances is the main reason for referral to Philippines National Poison Management and Control Center among other causes of acute poisoning. Rapid assessment of severity of injury is important for treatment and prognosis of these cases. This study was aimed to investigate the correlation of clinical factors with severity of gastrointestinal (GI) mucosal injury. In this retrospective study, a total of 105 patients were included. Patients were categorized into two groups including 35 patients with low grade and 70 patients with high grade GI injury to compare the predictive value of clinical findings. Mean (SD) age of patients was 27 (10) and 47% of patients were male. Oral burns (P<0.001), dysphagia (P=0.001), hematemesis (P<0.001), number of presenting symptoms (P=0.001), and type of substance consumed (P<0.001) were significantly different between patients with high grade and low grade GI injuries. Multivariate analysis showed that only leukocytosis was a significant predictor of higher grades of GI injury (OR=17.3, P=0.004). Nevertheless, dysphagia (OR=8.1), and higher number of manifestations (OR=2.8) on initial evaluation could be considered as weak factors as they did not reach significance (P=0.09). Following caustic substance injury, prompt assessment of severity of GI injury according to endoscopic and physical examinations can facilitate better treatment plan and prognosis. Patients with leukocytosis should be more carefully monitored as they might be injured with higher grades of GI mucosal lesions.