جستجوی مقالات مرتبط با کلیدواژه « sexually transmitted diseases » در نشریات گروه « پزشکی »

Correctly estimating the prevalence of sexually transmitted infections (STIs) is crucial for monitoring and managing these diseases effectively.

This study aimed to estimate the prevalence of STI syndromes and evaluate the surveillance systems for STIs in Marvdasht.

We conducted a cross-sectional study in 2018 involving a population-basedrandomsampleof 3 879 participants aged 18-50 in Marvdasht city. Genital ulcers and secretions in both genders were used as the primary outcomes to assess the completeness of the system and calculate the correction factor. A mathematical model was developed to estimate the correction factor for the prevalence of selected syndromes in each gender. The correction factor was determined by dividing the cases estimated through the mathematical model by the cases reported by the surveillance systems.

The estimated prevalence (with 95% confidence intervals [CI]) of urethral discharge in men and women, based on the model, was 25.32% (23.08 - 27.56) and 47.03% (39.93 - 54.13), respectively, and for genital ulcers, it was 5.16% (4.06 - 6.86) for men and 15.50% (9.5 - 21.5) for women. In both genders and for both syndromes, the reported prevalence by the care system (men: discharge 0.09% [0.07 - 0.11], ulcer 0.04% [0.03 - 0.06]; women: discharge 0.12% [0.1 - 0.15], ulcer 0.19% [0.16 - 0.22]) was severely underestimated. The highestandlowest underreporting correction ratios in the national STI monitoring system were observed for urethral discharge in men (124.5) and genital ulcers in women (7.26), respectively.

The study revealed that the reported prevalence of STI syndromes in Iran is significantly underestimated compared to the actual prevalence in the population. Fundamental revisions are necessary to enhance the system’s validity and completeness in detecting and reporting STIs.

Sexually transmitted infections (STIs) are frequently unreported, representing implied public health concerns, especially for women and in more vulnerable communities. This study aimed to determine the STI preventive behavior of Iranian women and related factors in protection motivation theory (PMT).

A cross-sectional online survey was conducted on a convenience sample from 20 January to 21 March 2021 in Iran. Women who were 18-35 years old with marital status were eligible to participate (N=600). The collected variables included demographic characteristics and STI-related behaviors regarding constructs of PMT: knowledge, perceived vulnerability, perceived self-efficacy, and preventive intention. A Persian version of the Korean four-scale about STI preventive behaviors was used as the assessment tool, and one-way ANOVA and Pearson correlation tests were used for analysis.

A significant difference was observed between knowledge, perceived vulnerability, perceived self-efficacy, and preventive intention with sociodemographic variables. STI-perceived vulnerability and STI-knowledge with mean scores of 62.37 and 42.52 were the highest and lowest perceived constructs of preventive behavior, respectively. STI knowledge of Iranian women was low, and STI-preventive self-efficacy was perceived as a positive predictor for STI protective behaviors.

A theory-based educational intervention is highly recommended to improve STI-protective behaviors.

HPV infections cause a wide spectrum of pathological changes in lower anogenital epithe- lium. The aim of this study was to investigate the HPV DNA status and histological findings in cervical biopsy specimens diagnosed as flat condyloma.

This study included 20 cervical biopsy specimens diagnosed as flat condyloma. The histopatholog- ical criteria and presence of HPV DNA were evaluated. HPV genotyping was determined in HPV-positive specimens using BioEdit software and the results were analyzed in SPSS software.

HPV DNA was not found in 30% of specimens and relative frequency of HPV genotypes was: 15% HPV6, 15% HPV11, 5% HPV16, 5% HPV18, 5% HPV53, 5% HPV68, 5% HPV84, 10% HPV45. Relative frequency of histopathologi- cal criteria was as below: 100% of specimens had koilocytosis, 100% acanthosis, 15% nuclear immaturity, 100% atypia, 15% mitotic activity, 50% dyskeratosis, 35% parakeratosis and 10% hyperkeratosis.

There were significant differences between HPV positivity and two pathologic criteria; multinucleation and hyperkeratosis (P Value: 0.02). Nuclear immaturity was significantly more prevalent in high risk HPV-positive specimens (P Value: 0.03).

Sexually transmitted infections (STIs) are among the most common infectious diseases and a globally concerning public health issue, especially in developing countries.

This study aimed to evaluate the syndrome-based point and lifetime prevalence of sexually transmitted infections in a big Iranian city.

This cross-sectional study was conducted in 2019 on a hospital-based random sample of 2107 people (men and women aged 15 - 50) at Marvdasht Central Hospital (Iran).

The lifetime prevalence of Sexually Transmitted Diseases (STDs) was significantly higher in women than in men (81.56% vs. 33.60%, P-value < 0.0001). Also, about 20.7% of men and 48.26% of women had at least one of the STIs-associated syndromes at the time of the interview (instantaneous prevalence) (P-value = 0.001).

The estimated prevalence of syndromes associated with sexually transmitted infections is alarmingly high. The results emphasize the need for further studies on effective health care and health promotion services to reduce STIs (including early detection and treatment of infections and public education).

Congenital infections are among the most important conditions threatening human fetal health, the majority of which are caused by viral agents. Screening pregnant women for viral infections is essential because such infections can cause serious consequences for both the mother and the infant. So, this study aimed to serologically investigate sexually transmitted viral infections in pregnant women and also find the association between the prevalence of viral infections and epidemiological parameters in pregnant women of Sari, Iran.

This descriptive, observational study was performed in pregnant women referring to Sari Birth Cohort Center between 2018 and 2020. Atotal of 1092 blood samples were investigated for hepatitis B(HBV), hepatitis C(HCV), human immunodeficiency virus(HIV), human T‑lymphotropic virus (HTLV), and cytomegalovirus (CMV) serological markers by enzyme‑linked immunosorbent assay (ELISA).

The prevalence of HBsAg positivity, HCV, HIV, and HTLV was 0.2%, 0.09%, 0.09%, and 0.2%, respectively. The percentage of participants with CMV‑IgM and ‑IgG antibody titers above normal was 0.2% and 91.8%, respectively. Pregnant women whose educational level was bachelor’s degree or lower, those who did not use a male condom before pregnancy, or those with a family history of infectious disease were found to be more likely to have HBV, HCV, HIV, HTLV, and CMV infections.

Family history, maternal age, pregnancy stage, and not using a male condom are among the risk factors for sexually transmitted viral infections in pregnant women in Sari.

The term transgender refers to those whose gender identity is different from their birth sex. Studiesestimate that gender-diverse persons represent 0.1-2% of populations investigated.1

Amongst sexually transmitted infections in the world, Trichomonas vaginalis is of the most common. Most of the infections are asymptomatic. It can infect women more than men because of genital tracts condition. The mother’s birth canal and perineum are common sources of infants’ eye infection. Some studies noted the possibility of T. vaginalis transmission through the birth canal to infants. Such an event can lead to neonatal conjunctivitis. By following Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines, a systematic review conducted to assess the possibility of neonatal conjunctivitis caused by T. vaginalis. Several factors can play a role in T. vaginalis transmission, such as low sanitary level, physical contact by contaminated biological fluids and infant’s opened eyes during the delivery. Through the review of different studies, it is inferred, although the probability of neonatal conjunctivitis caused by T. vaginalis is low, but it is possible. Finally, metronidazole is an approved drug for treatment of trichomoniasis and needs to consider in neonatal conjunctivitis caused by T. vaginalis.

Genital herpes has superseded the bacterial sexually transmitted diseases (STD) as the most prevalent STD seen worldwide, with an estimated 491 million being affected. It is encountered with an increasing frequency, with a prevalence of 11.9% in the USA, and can present in atypical and severe ulcerative forms, especially in human immunodeficiency virus (HIV)-infected individuals. Though a definitive antiviral treatment with acyclovir, valacyclovir or other derivatives exists, the property of latency and reactivation leads to its increasing incidence and prevalence. The common sites of involvement in the males are the glans, prepuce, and shaft of the penis. The male condom, if used appropriately, is the most effective among the barrier methods of contraception, with an additional advantage of protection from STDs. However, it has a failure rate of up to 13%. The efficacy of condoms in preventing herpes simplex virus 2 (HSV-2) transmission has been studied in several contexts; condoms are often associated with a decreased risk of HSV-2 transmission, yet fallacies can occur. Here, we describe a male who developed a primary episode of genital herpes at the base of the penis, despite proper usage of condoms during intercourse. This presentation can be likened to condom chancre, a much-described entity of primary syphilis.

Sexually transmitted infections (STIs) are one the most common infections in the world. Among them, anogenital warts and gonorrhea infections are a significant group of STIs.
We conducted this research to evaluate the prevalence of anogenital warts and gonorrhea infection and their related aspects in Iran. Still, it has a lot to know about its prevalence, trends, and risk factors.

In this cross-sectional study, 1064 patients voluntarily referred from a marriage counseling center to the  physicians in our center to evaluate STIs were enrolled in this study. All participants completed a data collection form about their sex, age, lifetime number of sexual partners, high-risk behaviors, and history of prior gonorrhea infection. They were also evaluated for anogenital warts by physical examination. The data were analyzed by SPSS 24 with Chi-square test, independent t-test, and logistic regression analysis. P-value <0.05 was considered significant.

The number of participants with current anogenital warts was 9.2% (11.9% in men and 3.5% in women). 1.1% of the participants had a documented prior gonorrhea infection, and all of these cases were men. After logistic regression analysis, there was a significant relationship between anogenital warts and gonorrhea infection and male gender (P=0.03). Also, there was a meaningful relationship between these diseases and the higher number of lifetime sexual partners (P=0.001).

Male sex and having more lifetime sexual partners are the risk factors for getting anogenital warts and gonorrhea infection.

The present study aimed to determine the prevalence of anti-syphilis antibodies in Iranian pregnant women who attended antenatal care (ANC) in 21 districts affiliated to Isfahan University of Medical Sciences (MUI) from April 2017 to April 2020.

In a cross-sectional study in 2020, the data about anti syphilis antibody were collected from electronic health files of pregnant women. Pregnancy specific health package was delivered to Iranian pregnant women in a horizontally integrated network across the country. The electronic health file was used for every Iranian citizen and all health events were recorded by their health care providers in 2016. All health services, particularly laboratory tests that were performed either in public or private laboratories, that were given to pregnant women needed to be recorded in their electronic health files. According to the pregnancy health package, they were screened initially by Rapid Plasma Reagin (RPR) test.

In those years, 70512, 72298, 63272 pregnant women were screened respectively. In these intervals, using the RPR test, no positive cases of anti- syphilis antibody were found.

It seems that syphilis infection among Iranian pregnant women who attended ANC in districts affiliated to MUI has reached the elimination phase.

Sexually transmitted diseases (STDs), especially in men, can lead to multiple morbidities and facilitate the transmission of serious pathogens, such as the human immunodeficiency virus. The present study used the data from a nationwide survey on male morbidities to estimate the prevalence of STDs among men in Iran.

This cross-sectional study used the data from a nationwide project on male reproductive morbidities in 2007. A total of 2296 men within the age range of 25 - 60 years were recruited by systematic cluster sampling from four provinces (i.e., Golestan, Hormozgan, Kermanshah, and Isfahan, Iran). The data on the symptoms of STDs, including genital secretion, pushing out, itching or genital ulcers, and lymphadenopathy of the inguinal area after sexual contact, were collected by trained urologists. Data analysis was carried out using SPSS software (version18.0, Chicago, IL, USA). The independent samples t-test and chi-square test were used for data analysis.

A total of 2296 men with a mean age value of 39.95 ± 10.3 years were interviewed in this study. Two-thirds of all the subjects (75%) were aware of using condoms in suspected sexual relationships; however, only 69% of the aforementioned subjects used condoms in those circumstances. Overall, 14 subjects (0.6%) had one type of STDs at the study time. Moreover, 110 subjects (4.7%) answered “yes” to the question of whether they were referred to a physician for sexual problems.

The prevalence of STDs is still low among the male population in Iran. Careful and well-designed surveillance systems to monitor the incidence of STDs and proper preventive measures to restrict the spread of sexually transmitted pathogens are among the proposed recommendations.

 Sexually transmitted infections (STIs) constitute a major public health problem in both developed and developing countries. Human immunodeficiency virus (HIV) and STIs are linked in their similar mode of transmission, with STIs facilitating the acquisition and transmission of HIV. The prevalence pattern of individual STIs may evolve over time necessitating a corresponding change in management strategies.

 The study was conducted to determine the burden and any change in the etiological trend among attendees of an STIs clinic at a tertiary care hospital.

 This retrospective study analyzed data retrieved from consecutive patients attending an STIs clinic over two years (July 2018 to July 2020).

 Overall, 1916 patients were diagnosed with STIs. The predominant age group was 25 - 44 years (59.23%). Genital ulcer disease was the foremost syndrome (1213, 63.3%). Overall, herpetic genital ulcer was the most common (682, 35.6%), followed by non-herpetic ulcers (531, 27.7%). Vaginal discharge, lower abdominal pain, and urethritis were found in 461 (24%), 219 (11.43%), and 23 (1.27%) of the patients, respectively. Amongst 237 (12.36%) In HIV seropositive attendees, genital ulcer disease (herpetic) was the most common syndrome (179, 75.53%), followed by vaginal discharge (42, 17.72%), lower abdominal pain (9, 3.8%), and urethritis (7, 2.9%).

 A definite change in the profile of STIs was observed with ulcerative STIs (particularly herpes genitalis) constituting the major burden against a discernible back drop of decreasing non-herpetic STIs. A systematic, regional, periodic synopsis would not only help to follow and document the dynamic trends, but also can help to assess the effectiveness of control programs.

Context:

Street children may expose to high-risk behaviors such as unwanted pregnancy, abortion, and sexually transmitted diseases (STDs).

This study aimed to systematically review and present preventive strategies for promoting the sexual and reproductive health (SRH) in domains such as unsafe abortion, STDs, and unwanted pregnancy in the street children.  

Data Source and Selection:

In this systematic review databases such as ScienceDirect, Web of Science [ISI], PubMed, Scopus, Scientific Information Database [SID] and Google Scholar were searched. Published articles between 1990 and 2020 were retrieved. Finally, 41 articles were used to compile the results of this study.

Data Extraction:

Data were extracted from the articles according to the selection criteria by two independent reviewers.

A total of 1522 potentially relevant articles were identified, 275 articles were removed due to the duplication and in abstract screening, 766 articles did not meet inclusion criteria or did no focus on research question. 481 remained articles were screened for full-text and studies which were published each language expect English and Persian, studies presented in conferences and also studies which have no information regarding the SRH among street children were removed. Finally, 41 studies were included in this systematic review. Results of this study were categorized into 2 main tables. In table 1, the SWOT of SRH in street children was shown and in table 2, preventive strategies regarding unwanted pregnancy, unsafe abortion, and STDs in the street child were systematically presented in four categories such as expansion program and promotion of educational services, 2- expansion program and promotion of educational services, 3- Creating secure umbrella and social welfare and 4- expansion program and promotion of social protection. 

In conclusion, due to the lack of information on street children regarding SRH, the government should consider adequate sexual education programs such as protected sexual intercourse and counseling on the prevention of STDs and also unsafe abortion. Considering the affordable, accessible healthcare centers and facilities with providing services with no judgment for these children is an important action.

Cervical cancer is known to be a preventable cancer in which various risk factors play role in increasing the risk of the disease. In this study, we have assessed different risk factors involved in invasive cervical cancer in Northeast of Iran.

In a case control study, 100 patients with advanced cervical cancer were compared to 100 healthy, normal women. In addition, 100 cases of prisoner women who had a high risk profile for cervical cancer were also investigated. Cervical risk factors for these groups were documented using a questionnaire and available medical notes. Univariate analysis was done for each risk factor followed by a multivariate regression analysis to evaluate the most powerful risk factors after adjustment.

Age of first intercourse ≤16 (P<0.001)[OR= 4.18, 95% CI (2.32-7.54)], sexually transmitted diseases (STD) (P<0.001) [OR=8.59,95% CI (4.25-17.37)], passive smoking (P<0.01) [OR= 2.35, 95% CI (1.17-4.72)], smoking (P<0.01) [OR=10.33, 95% CI (2.32-46.17)], age of first pregnancy ≤17 years (P<0.001) [OR= 3.37, 95% CI (1.79-6.33)] were strongly related to the occurrence of cervical cancer. However, STD remained statistically significant (P<0.01) after adjustment.

Homeless women are at high risk of sexually transmitted infections (STIs) due to their adverse early-life experiences.

This study aimed to examine the association between adverse early-life experiences and the risk of acquiring STIs among homeless women in Tehran.
Patients and

A descriptive-analytical cross-sectional study was carried out in 2014. The study recruited 241 homeless women through quota sampling from the drop in centers and shelters affiliated to a local welfare organization in Tehran, Iran. Data were obtained using questionnaires on demographics and adverse early-life experiences. Blood and urine samples were tested for human immunodeficiency virus (HIV), herpes simplex virus 2 (HSV-2), syphilis, Chlamydia trachomatis, and Neisseria gonorrhea. Descriptive statistics including frequency were calculated for all variables. To analyze the data at a significance level of 0.05, binary logistic regression was used.

The prevalence rates of HIV/AIDS, HSV-2, syphilis, Chlamydia trachomatis, and Neisseria gonorrhea were 8.29%, 23.65%, 14.93%, 11.61%, and 6.63%, respectively. The results of logistic regression showed that the risk of acquiring STIs increases by factors such as sexual abuse (OR = 4.06; 95% CI = 1.21 - 13.6, P = 0.02), running away from home (OR = 4.46; 95% CI = 1.67 - 12.89, P = 0.03), drug use (OR = 3.93; 95% CI = 1.13 - 13.58, P = 0.03), alcohol use (OR = 4.12; 95% CI = 1.38 - 12.24, P = 0.01), imprisonment and criminal records (OR = 2.72; 95% CI = 1.01 - 7.52, P = 0.04), premarital sexual activity (OR = 4.71; 95% CI = 1.06 - 13.84, P = 0.05), divorce (OR = 3.47; 95% CI = 1.06 - 11.32, P = 0.03), Nikah mut’ah (OR = 4.33; 95% CI = 1.39 - 13.49, P = 0.01), having multiple sex partners (OR = 5.2; 95% CI = 1.81 - 14.96, P = 0.02), and having unprotected sexual relationships (OR = 3.69; 95% CI = 1.00 - 13.62, P = 0.05).

Homeless women had high rates of adverse early-life experiences and overall 41.49% of them were affected at least by one STI. Future interventions should focus on the reduction of adverse early-life experiences, especially during adolescence, including the promotion of adolescent empowerment, promotion of condom use, and improvement of awareness of STIs.