جستجوی مقالات مرتبط با کلیدواژه « success rate » در نشریات گروه « پزشکی »

This study aimed to evaluate the effect of different premedication protocols on the success rate of the inferior alveolar nerve block (IANB) technique in mandibular molars with irreversible pulpitis. Two hundred and ten participants were randomly assigned into three groups (n=70) and received one of the following premedications 30 minutes before IANB injection: dexamethasone, pharmapain (containing acetaminophen, ibuprofen, and caffeine), and a placebo lactose capsule. Pain severity was evaluated with the Heft–Parker visual analog scale (VAS) before and 15 minutes after the injection, during dentin removal, and when inserting files into the root canal. The IANB injection was considered successful if VAS values after 15 minutes implied no pain or mild pain.  IANB success rates were comparable in the dexamethasone (51.4%), pharmapain (55.7%), and placebo (41.4%) groups (P=0.222). Pain severity at baseline, 15 minutes post-injection, and during dentin removal was comparable among the groups (P>0.05). However, when inserting endodontic files, the mean pain severity in the pharmapain group was significantly higher than the dexamethasone group (10.27 ± 1.71 versus 7.38 ± 2.24; P=0.002). No significant difference was observed between the placebo with any of the study groups (P>0.05). Premedication with pharmapain (an anti-inflammatory agent) or dexamethasone (a corticosteroid) does not enhance the success rate of the IANB technique in mandibular molars with irreversible pulpitis compared to placebo. However, the use of dexamethasone was significantly more effective than pharmapain in reducing pain severity at inserting endodontic files.

Although the invention of more specialized duodenoscopes helped to develop Endoscopic Retrograde Cholangiopancreatography (ERCP) as a Therapeutic Method in children, there is a general perception that ERCP is practically challenging and dangerous in children. This has limited its widespread use in children. The aim of this meta-analysis is to update the previous reviews and evaluate more recent outcomes and complications of therapeutic ERCP among children with HPB disease.

A systematic literature search based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was performed in Web of Science, Embase, PubMed, and Cochrane library databases to find and evaluate all articles regarding therapeutic ERCP in children with HPB diseases published from January 2017 to July 2022. The analysis included studies that evaluated patients less than 18 years old undergoing ERCP with the objective of HPB diseases, and had reported the success rate and side effects. The main outcome measures were the success and complication rate of therapeutic ERCP. This meta-analysis was performed using STATA version 16 (StataCorp LP, College Station, Texas).

A total of 10 articles consisting of 1924 ERCP, performed on 958 children, were included. Out of all ERCPs, 96% (95%CI: 96-97, I2:95.8%) were conducted with therapeutic goals. The overall success rate among therapeutic ERCPs was 91% (95CI:90-92%, I2:97.1%) ranging from 65% to 95% among different studies. An overall of 9% (95%CI: 8-10, I2:97.8%) of all therapeutic ERCPs were associated with different adverse effects such as postoperative pancreatitis (6%) and Hemorrhage (1%).

Our analysis suggested ERCP as a safe therapeutic method for pediatric patients suffering HPB patients, having a success rate of 91% and a complication rate of 9%, none of which led to in-hospital mortality.

High-quality pit and fissure sealant (PFS) treatment can promote public oral health. The present study aimed to compare the success and survival rates of PFS treatments performed by dental students and postgraduate students in pediatric dentistry, and to evaluate the associated patient-related factors. Patients who had received at least one PFS treatment performed by an undergraduate or postgraduate student during 2016-2018 were recalled. The age and gender of the patients, caries risk, oral hygiene status, DMFT, dmft, and the status of the PFS treatment in terms of retention rate and caries development were evaluated. The chi-square test, multiple logistic regression model, and Weibull accelerated failure time regression model were applied for statistical analysis. The success and survival rates of PFS treatments in the postgraduate group were significantly higher than those in the undergraduate group (P<0.05). Moderate caries risk and permanent tooth type were significantly associated with lower success rates of PFS therapy (P=0.02 and P=0.003, respectively). Additionally, increased dmft, moderate caries risk, and permanent tooth type were associated with shorter survival times (P<0.001, P=0.01, and P=0.009, respectively). High caries risk also decreased both success and survival rates of PFS treatment, but these alterations were not statistically significant (P=0.26, and P=0.55, respectively). The success rate of PFS therapy is influenced by patient-, tooth-, and operator-related factors. PFS treatment is assumed to be more successful when performed by postgraduate students in the primary teeth of patients with low caries risk. (J Dent Mater Tech 2023;12(2):(73-81)

To investigate the Risk factors for AGV ( Ahmed glaucoma valve) failure.

A retrospective review was conducted on the medical records of patients with varying causes of glaucoma who had undergone AGV implantation. The primary measure of success was the cumulative achievement of an intraocular pressure (IOP) between 5 and 21 mmHg, with a 20 % reduction from baseline, with or without medication to lower IOP. The secondary measures of success were the IOP levels and the number of medications used for glaucoma treatment.

The study enrolled a total of 120 participants, with an average age of 48.9 ± 19.6 years and an average follow-up period of 4.5 ± 1.4 years. The mean survival duration was 5.3 ± 0.5 years in patients with high pressure (HP), which was significantly shorter than the 6.4 ± 0.2 years in those without HP. The likelihood of surgical failure increased with higher baseline IOP, with an odds ratio of 1.07 (95 % confidence interval: 1.02-1.12). In a logistic regression model, neovascular glaucoma was the only factor significantly associated with the occurrence of HP, with an odds ratio of 3.14 (95 % confidence interval: 1.2-8.1).

Neovascular glaucoma and a Higher Baseline IOP are risk factors for AGV failure.

Pulp treatment in primary dentition is generally divided into vital and non-vital pulp therapies and assists in the preservation of pulpally involved primary teeth in the dental arch until the affected tooth naturally exfoliates. The success of pulp therapies depends on several factors; e.g.proper case selection, accurate diagnosis and good coronal seal. To date, studies on the success and failure rates of pulp treatments are based on clinical signs and symptoms, radiographic findings and histological analysis. However, the clinical and radiographic evidence may not completely portray the true status of the dental pulp. Histological evidence remains the gold standard in the assessment of pulp condition, whether it is in a healthy or adverse state. The aims of the current research were to summarise the treatment outcomes of pulp therapy in primary dentition based on clinical, radiographic and histological criteria, and to support its relevance in the presence of limited histological evidence to measure authentic treatment success. An electronic database search of dental literature from 1990 to 2022 was carried out using the MEDLINE, i.e. PubMed,database. Current dental literature showed that the success rates of primary tooth pulp therapy are high. The obtained results were based largely on clinical and radiographic studies with narrow histological investigations to assess the treatment outcome(s) of pulp therapy in primary dentition. Despite the scarcity of histological evidence, pulp therapies in primary teeth are still practical due to their statistically empirical success compared to their failure. Consequently, pulp therapy of primary dentition is still relevant, and should continue to be indicated as an important treatment option.

</span> Periapical surgery is a reliable method for treating teeth with periapical lesions for which conventional root canal treatment methods are not effective. The aim of this study is to investigate the results of periapical surgical treatment after a follow-up period of one to five years and the factors related to the success rate of the treatment.</span></span></span>
</span> In this cross-sectional study, complete clinical and radiographic examinations were performed on 128 patients who underwent periapical surgery in the endodontics department of Mashhad Dental School. The success of the treatment was evaluated based on radiographic and clinical criteria for three groups: recovered, recovering and non-recovering. The patients were examined in terms of the relationship between the success rate of periapical surgery and the variables of age, gender, type of tooth, type of jaw, presence of post, type of coronal restoration and the presence of preoperative symptoms.</span></span></span>
</span> From a total of 128 patients, 64 patients including 35 women and 29 men were studied. The results showed that the number of successful treatments is higher in women and in anterior teeth, although their difference was not statistically significant. In the age range of 11 to 30 years, all treatments were successful, with a treatment success rate of 89% in the recovered and recovering groups. In addition, there was no statistically significant difference in the success rate of periapical surgery in terms of factors such as the type of jaw, the presence or absence of a post, the presence of symptoms before treatment, and the type of tooth restoration.</span></span></span>
</span></span> The results of this study showed that periapical surgery can be considered as an effective treatment method for patients. In addition, factors such as age, gender, type of jaw, presence or absence of post, presence of symptoms before treatment and type of tooth restoration do not have a significant effect on the treatment result.</span></span></span></div>

Success in anesthesia administration relieves the perception of pain during surgery. Lidocaine is the most commonly used local anesthetic agent in clinical medicine. Moreover, anesthetic agents’ temperature changes can influence cell membrane permeability. Here, the effectiveness of different temperatures of Lidocaine (Lid.) on anesthesia success rate has been investigated in rats.

Wistar male rats were pretreated by fast injection of lidocaine or saline into the hind paw or intradermal cheek at Room Temperature (RT) and Body Temperature (BT) (22°C and 37°C, respectively). Then, rat behaviors were evaluated by formalin-induced hind paw pain and orofacial pain tests, respectively. Moreover, using a single-unit recording technique, the spontaneous activity of the marginal nerve was recorded at room temperature in the RT-Lid. and BT-Lid. groups.

Data analysis revealed that lidocaine had significant antinociceptive effects in both the BT-Lid. and RT-Lid. groups compared to the control groups (P<0.05). Also, the number of spikes in the BT-Lid. and RT-Lid. groups were significantly lower than their baselines (P<0.05). However, lidocaine at body temperature decreased the total time spent licking the hind paw, the number of lip rubbings, and the number of spikes firing by about 10%-15% compared to room temperature.

In both behavioral and neural levels of the study, our results showed that an increase in the temperature of lidocaine toward body temperature could increase anesthesia success rate compared to administration of lidocaine at room temperature. These findings can be considered in the treatment of patients.

Renal stone disease is a very common disease, and its lifetime prevalence is 1 - 15%, with a gradual rise in incidence and disease prevalence. There are significant financial implications of its management. Nowadays, for big (typically > 2 cm) renal and upper ureteric stones, PCNL is widely regarded as the first-line treatment. Because most of the intrarenal collecting systems can be accessed by superior calyceal puncture in PCNL, good stone clearance can be achieved. The “Guy’s Stone Score” is a useful technique for categorizing the complexity of PCNL.

This study aimed to evaluate the role of Guys Stone Score based on KUB and intravenous urography to predict the success rate, grading, and complexity of PCNL, which are performed via the upper pole access.

The present prospective, non-randomized observational study was undertaken in the Department of Urology and Renal transplantation, SCBMCH, Cuttack, from 1st November 2017 to 31st October 2019. A total of 104 patients were enrolled in the study in whom PCNL was performed through superior calyceal puncture, based on preoperative intravenous pyelogram. The Guy’s Stone Score was calculated, and the complexity of the procedure was graded using radiological studies, then the outcome was determined accordingly.

In this study, 59.6% of the patients had immediate success among them 29.0% had grade 3, and 6.5% had grade 4 GSS. Moreover, 38.4% of the patients had clinically significant residual fragments among them, 75.0% had grade 4, and 20.0% had grade 3 GSS.23% of the patients underwent REDO-PCNL and 11.5% of the patients underwent accesory/ancillary procedure of ESWL.

The present study shows that an intravenous pyelogram-based Guy’s Stone Score (GSS) is an easy-to-use tool in predicting the early success rate and potential difficulties and complications in PCNL performed through superior calyceal puncture.

To validate the standard values and evaluate the success rate in the treatment of minor and major trichiasis using thermoablation with a diode green laser.

In this interventional prospective study, individuals with minor or major trichiasis who were treated with thermoablation using diode green laser were included. The patients’ mean age was 72.1 years; the majority were females (54.1%) and Caucasian (98%). The parameters of the diode laser were wavelength of 532 nm, application time of 200 ms, target size of 50 μm, interval between the shots 150 to 200 ms, and power of 600 to 750 mW. The number of shots was defined by the depth of ablation sufficient to reach the pilus hair bulb. The patients were evaluated by slit-lamp every 3 to 4 months, for up to 15 months. The treatment success rate and the association between variables were analyzed.

The study sample was comprised of 98 patients with 135 affected lids and 337 lashes with trichiasis. Minor trichiasis (91.8%), unilateral trichiasis (67.3%), trichiasis affecting the lower eyelid (85.9%), and trichiasis resulting from blepharitis (64.3%) were the most common presentation profiles. The overall cure rate at the end of the study was 85%, with 69% being cured with a single session and 82.8% with two treatment sessions.

Thermoablation using a diode green laser applying the specified parameters to treat minor and major trichiasis is effective and results in high cure rate.

To study the success rate of LASER as a primary modality of treatment in aggressive posterior retinopathy of prematurity (APROP) cases.

This is a prospective case series of 56 eyes of 28 preterm babies (males = 21) with APROP who underwent laser therapy. Babies were divided into groups on the basis of gestational age (GA), birth weight (BW), and postmenstrual age (PMA) at which treatment was performed. GA (in weeks): <28 (n = 7), 28–30 (n = 11), >30 (n = 10). BW (in grams): <1000 (n = 8), 1000–1200 (n = 10), >1200 (n = 10). PMA (in weeks): < 32 (n = 6), 32–34 (n = 18), >34 (n = 4). Success was calculated as complete regression of disease without need for any other modality of treatment such as anti-vascular endothelial growth factor (anti-VEGF) or pars plana vitrectomy.

The overall success rate was 94.64% (53/56). Two babies who needed additional modality of treatment were <28 weeks of GA (one eye) and 28–30 weeks (two eyes). One baby (one eye) was <1000 gm and the other (two eyes) was >1200 gm, while PMA at which additional treatment was needed was 30 weeks in one baby (one eye) and 33 weeks in the other (two eyes).

In this era of anti-VEGF treatment, even in cases of APROP, LASER should still be considered as a primary modality of treatment, as it is a one-time treatment without the concern of systemic side effects and recurrent/persistent avascular zones.

Most deaths occur unpredictably and usually outside of health care facilities; while could be predicted by Cardiopulmonary Resuscitation (CPR). Whatever, the success rate of this procedure is affected by many factors and the aim of this study was to evaluate CPR outcomes and determine theassociated factors. This descriptive retrospective study was conducted in 2018 in a private hospital in Mashhad. Census method was used for sampling, and all the patients who underwent CPR were included in the study. Meanwhile, those who had signs of death and/ or those with incomplete medical records excluded from the study. Moreover, data were provided through the Statistics, Medical Records as well as Quality Improvement units. In this study, 394 medical records were evaluated, out of which 224(56.9%) were male and 170(43.1%) were female. Totally, 96(24.4%) successful and 298(75.6%) unsuccessful CPR were recorded. There was a significant correlation between age of the patientand successful CPR (P=0.011). Results of the study showed that the success rate of CPR will be higher, if the patient is young, duration of CPR is short, and the patient has a non-cardiac underlying disease.

To compare the efficacy of parasagittal interlaminar (PIL) and midline interlaminar (MIL) approaches for epidural block in patients with lower limb orthopedic surgery. This double-blind randomized clinical trial was performed on 40 patients undergoing tibial shaft fracture surgery. In PIL group, an 18-gauge, 3.5 inch, Tuohy needle was placed at the level of L2-3 or L3-4 intervertebral spaces and pushed forward in a posteroanterior (PA) direction vertical to the body surface. After determining the most lateral place for needle arrival in an anteroposterior (AP) view, needle was pushed forward into the epidural space. For the MIL group, needle was pushed forward from the midline interspinous space with the same method. After confirmation of needle position, 1 mL of contrast was injected to confirm the epidural space distribution and then 15 ml lidocaine 2% was injected. The sensory and motor block level, onset, duration, heart rate (HR), mean arterial pressure (MAP), and arterial oxygen saturation (SPO2), and success rate were recorded. Mean patients’ baseline characteristics showed no statistically significant difference between the two groups. (p>0.05). Outcome measures were statistically different and significantly higher in PIL group (p-values for sensory block level <0.001, motor block level <0.001, duration of sensory block: <0.001 and duration of motor block <0.001 and success rate: <0.001). Hemodynamic variables didn’t show statistically significant difference between the two groups (p-values for Systolic pressure: 0.997, diastolic pressure:0.579, MAP:0.585, HR:0.710). Epidural anesthesia with parasagittal interlaminar approach provide deep motor block, high sensory level block, and hemodynamic stability.

Cardiopulmonary resuscitation (CPR) success rate is an important issue for allhealthcare facilities. In the present study, success rate and related factors were assessed in a hospitalin Iran. This descriptive-correlational study was conducted in 2017. By using the conveniencesampling, 156 patients were selected. Variables based on the In-Hospital Utstein-Style were used,which included 3 categories: patients, cardiac arrest and follow-up. Data were analyzed by SPSS 22. Of 156 participants, 92 were male and the average age was 61.4±5.5 years. Most cardiacarrest occurred in night shift (43.6%). The most common cause of cardiac arrest was cancer (33%). Of156 patients, 102 died. Results showed a significant correlation between success rate, a patient’s sex,rhythm type and medication administered during resuscitation (P < 0.001). Success rate in our study was low in comparison to previous studies. Further attentionshould be paid to this issue.

Cardiopulmonary resuscitation (CPR) procedure consists of measures taken to restore the acts of the heart and the brain in a person who has lost their own consciousness. Thus, the purpose of the present study was to investigate the success rate of Cardiopulmonary Resuscitation, survival rate in patients, and their related factors in order to assist in improving effective conditions and measures within hospitals to increase the success rate of CPR.
This cross-sectional analytic study was conducted in 2016. To this end, a total number of 199 patients affected with cardiopulmonary arrest and undergoing the CPR procedure in the emergency wards and other hospitals units in Iran were recruited using a convenience sampling method. Then, patient information was collected through a researcher-designed checklist as well as a review of clinical records. The data were also analyzed via the SPSS.16 software. Data analysis was similarly performed using descriptive statistics and Chi-square and t-test.
The mean age of patients was 44 years. The result of 36.7% of CPR procedures conducted was reported successful, however, only 4% of patients finally survived. In general, the findings revealed that factors such as age, gender, hospital, history of prior diseases, checked initial rhythm, work shift, time of work shift change, pre-resuscitation intubation status, and underlying cause of cardiopulmonary arrest had no effects on the success rate of CPR procedure. However, location of the occurrence of cardiopulmonary arrest (P = 0.03) and specialty of physicians in charge of resuscitation teams (P = 0.01) were among the factors affecting the success rate of CPR procedure. Furthermore, checked initial cardiac rhythm (P Given the simplicity and teachability of the principles of basic life support (BLS), health status, and survival rate in patients can be easily and significantly promoted through the public education of the initial resuscitation measures. Moreover, according to the investigations made in this respect, post-resuscitation measures can dramatically affect the survival rate of individuals. Therefore, it is suggested to investigate post-resuscitation measures in other studies of prospective type in order to propose strategies to improve the survival rate of patients.

The purpose of this study was to evaluate the results of a teamwork revision endoscopic dacryocystorhinostomy (DCR) in eyes with previously failed external DCR.
This retrospective study was performed on 50 failed external DCR subjects who underwent a teamwork revision endoscopic DCR by an ophthalmologist and an otolaryngologist. Paranasal sinus CT scanning was performed for each patient before the revision surgery. During surgery, any abnormal tissue noticed before silicone intubation was sent for pathological evaluation.
Endoscopic revision DCR was performed on 50 failed external DCR subjects with one‑year follow‑up. Of these, 31 were female (62%). The age range of the subjects was 18‑88 years (mean: 59.98 years). Sinus CT showed at least one abnormality in 94% of cases. Revision endoscopy showed septal deviation (66%), scar formation (32%), ostium problems (28%), and sump syndrome (6%). Pathologic and clinical findings showed that chronic inflammation had a significant association with scar tissue and septal synechia (P = 0.001 and 0.008, respectively). At the final follow‑up, anatomical and functional success was achieved in 45 out of 50 (90%) of subjects.
Endoscopic revision DCR when performed as cooperation of otolaryngologists and ophthalmologists may help resolve the endonasal problems and increase the success rate.

To compare the visual outcomes of deep anterior lamellar keratoplasty (DALK) for keratoconus with and without successful big-bubble formation.
In this retrospective comparative study, a total of 289 consecutive eyes from 257 patients underwent DALK using the big-bubble technique. In cases where the big bubble could not be accomplished, manual stromal dissection down to Descemeton membrane (DM) was performed using a crescent knife. Visual acuity and refractive outcomes were compared between the bare DM group (Group 1) and manual dissection group (Group 2).
A bare DM was successfully achieved in 229 (79.2%) eyes and manual dissection was performed in 60 (20.8%) eyes. The study groups were comparable in terms of age (P = 0.79), preoperative best-spectacle corrected visual acuity (BSCVA) (P = 0.15), and follow-up duration (P = 0.73). Postoperative BSCVA was significantly better in Group 1 than in Group 2 throughout follow-up (P Retention of the posterior corneal stroma which occurs with manual dissection during failed big bubble formation in DALK is associated with lower visual acuity as compared to achieving a bare DM.

To compare the visual outcomes of deep anterior lamellar keratoplasty (DALK) for keratoconus with and without successful big‑bubble formation.
In this retrospective comparative study, a total of 289 consecutive eyes from 257 patients underwent DALK using the big‑bubble technique. In cases where the big bubble could not be accomplished, manual stromal dissection down to Descemeton membrane (DM) was performed using a crescent knife. Visual acuity and refractive outcomes were compared between the bare DM group (Group 1) and manual dissection group (Group 2).
A bare DM was successfully achieved in 229 (79.2%) eyes and manual dissection was performed in 60 (20.8%) eyes. The study groups were comparable in terms of age (P = 0.79), preoperative best‑spectacle corrected visual acuity (BSCVA) (P = 0.15), and follow‑up duration (P = 0.73). Postoperative BSCVA was significantly better in Group 1 than in Group 2 throughout follow‑up (P Retention of the posterior corneal stroma which occurs with manual dissection during failed big bubble formation in DALK is associated with lower visual acuity as compared to achieving a bare DM.

To compare trabeculectomy with mitomycin-C (MMC) application before versus after scleral flap dissection in terms of corneal endothelial cell loss and surgical outcomes.
In this double blind clinical trial, patients were randomized to MMC 0.02% application before (group A) or after (group B) scleral flap dissection. The main outcome measure was corneal endothelial cell density; secondary outcome measures included IOP, glaucoma medications, success rates (IOP ≤21 and ≤18 mmHg, defined as criterion 1 and 2, respectively) and complications.
Overall, 99 eyes of 99 subjects including 72 male and 27 female subjects were operated and followed for at least 6 months. The study groups were comparable in terms of baseline variables. Outcomes of surgery were similar at six months in terms of IOP (11.8±5.8 vs. 11.7±5.5 mmHg, P=0.88) and number of medications (0.2 ±0.6 vs 0.1±0.4, P=0.45). Overall success was comparable at months 1 and 3, but higher in group B at month 6 (82.0% vs. 63.3%, P=0.036 for criterion 1 and 78.9% vs. 59.2%, P=0.044 for criterion 2). Hypotony was more prevalent in group B (8.0% versus 2.0%) but the difference was not significant (P 0.38). Endothelial cell density loss (2.2±7.3 vs 0.9±6.3%, P=0.567) was comparable between the study groups.
Corneal endothelial loss following trabeculectomy was comparable with MMC application before and after scleral flap dissection. The sequences were comparable in terms of postoperative IOP and glaucoma medications. Overall success rate was higher at six months in group B and the rate of hypotony was also higher, although insignificantly.