جستجوی مقالات مرتبط با کلیدواژه "sumac extract" در نشریات گروه "پزشکی"

Beef meat is highly prone to microbial spoilage as it is rich in essential nutrients and putrefying in nature. Nowadays, consumers are applicant to usage of natural replacements causing to side effects of synthetic preservatives such as carcinogenicity and teratogenicity.
In this study the influence of hydro alcohol sumac extract (SE) and chitosan coating alone or in combination with Z. multiflora Boiss essential oil (ZEO) added, on microbial attributes of beef meat were investigated during refrigerated storage in normal and modified atmosphere packaging (MAP: 80% oxygen and 20% dioxide carbon). The samples were stored at 4 °C for 20 days and microbial analysis were conducted at zero, four, eight, 12, 16 and 20 days.
Total viable counts, lactic acid bacteria, Pseudomonas spp., Enterobacteriaceae and yeasts- molds were significantly lower in all treatments than control over the storage time. The highest level of antimicrobial effect of chitosan, SE 4% and ZEO were found on TVC (by 3.69 and 4.04 log CFU/g (colony forming unit / gram) reduction compared with control), Enterobacteriaceae (3.61 and 3.73 log CFU/g reduction) and lactic acid bacteria (2.67 and 2.53 log CFU/g reduction), in normal packaging and MAP, respectively.
These results suggest the potential of chitosan, SE and ZEO as biopreservatives under refrigerated storage in normal packaging and MAP.

Herpes simplex virus type 1 (HSV-1) is a common virus in human. The rate of drug resistance is increasing in HSV-1. In this study¡ anti-viral effects of Rhus coriaria L. fruit extract was evaluated against acyclovir resistant HSV-1 before¡ during and after the infection of Hela cell line.
In this experimental study¡ the trypan blue and 3-[4¡5-dimethylthiazol-2-yl]-2¡5 diphenyltetrazolium bromide (MTT) tests were used to rule out the potential toxic effects extract on the Hela cell line. Antiviral effects of the extract on acyclovir resistant HSV-1 were evaluated before the infection and at different concentrations of the extract. The effective minimal cytotoxic concentration was assessed at different times of virus replication after virus adsorption. Virus titer was determined by tissue culture infectious dose 50 (TCID50) method.
The CC50 value and effective minimal cytotoxic concentration were determined at 780 µg/ml and 390 µg/ml respectively. Treatment of HSV-1 with extract resulted in 1 log10 TCID50 reduction in virus titers after 3 and 4 hour. The highest reduction in acyclovir resistant HSV-1 infectivity was obtained 2 and 4 hour after the infection of the cells with virus resulting in 1.7 log10 TCID50 reduction as compared with control.
The antiviral effects of Rhus coriaria L. fruit extract on acyclovir resistant HSV-1 after virus infection was more remarkable than the treatment of virus with the extract before virus adsorption. Keywords: Sumac extract¡ Antiviral effects¡ Herpes simplex virus type 1.