جستجوی مقالات مرتبط با کلیدواژه « supratentorial » در نشریات گروه « پزشکی »

Ependymomas are glial tumors originate from ependymal cells lining the ventricles and the central canal of the spinal cord. Two thirds of ependymomas arise in the infratentorial or intraventriclesandone-third aredetected in supratentorial area. However supratentorial “cortical” ependymomas are veryuncommon. Ependymomas are usually infratentorial, intraventricular tumor, including 2–9% of all central nervous system tumors. We present a unique case of an anaplastic cortical ependymomain a 48-year-old man. The patient presented with transient amnesia and right weakness and seizure. This tumor was located in the left parieto-occipital region with extension to corpus callosum and thalamus. Microscopy and immunohistochemistry showed grade III differentiation ependymoma.

Ependymomas are glial tumors derived from ependymal cells lining the ventricles and the central canal of the spinal cord. Two thirds of ependymomas arise in the infratentorial or intraventricles, whereas one‑third are located in supratentorial space. But supratentorial “cortical” ependymomas are very rare. We report a case of a cortical ependymoma in a 17‑year‑old boy. The patient presented with transient recurrent right weakness and diplopia. This tumor was located in the left parieto‑occipital region and he had gross total excision. Microscopy and immunohistochemistry showed grade III differentiation ependymoma.

In this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to MAHAK Pediatric Cancer Treatment and Research Center (one of the main national referral centers for childhood malignancies in Iran) for treatment. This cohort (simple sampling) study consisted of 198 children less than 15 year old with CNS tumor referred to MAHAK Pediatric Cancer Treatment and Research Center from 2007 to 2010. The unique checklist contained epidemiological features filled for each individual. Out of studied patients 125(63.1%) were male and 73(36.9%) were female. The mean age of patients was 6.11±3.65 years. Tumors were located in supratentorial (N=60, 30.3%), infratentorial (N=134, 67.7%) and spinal (N=4, 2%) regions. High-grade glioma and medulloblastoma were the most common tumors in supratentorial and infratentorial locations respectively. The majority of patientin medulloblastoma group had T2M0 (N=44, 22.2%) stage. Thirty-one (15.7%) patients had arelapse. There were 38.4% treatment and 41.4% death. The five years survival rate among patients was 28%. The same frequency of CNS tumors in children less than 15 years old referred to MPCTRC was observed compared to other studies. The sex incidence, the mean age at presentation, tumor sites, brain tumor’s pathologies, signs and symptoms, metastases and relapses were also in line with other studies. There were significant differences in terms of high consanguinity rate and high incidence of familial cancer history as compared to reports from others.