جستجوی مقالات مرتبط با کلیدواژه "umbilical artery ph" در نشریات گروه "پزشکی"

In many deliveries, determination of umbilical artery PH is considered a suitable tool for predicting the risk of damage to the fetus and determining the likelihood of associated complications. This study was performed in order to investigate the relationship between maternal risk factors and umbilical artery PH in premature infants. In this case-control study, 600 premature neonates (gestational age of 27-37 weeks), were examined in terms of umbilical artery pH within the first 5 minutes after birth. In total, 181 newborns suffering from acidosis with pH> 1.7 (case group) and 419 neonates without acidosis (control group) were compared in terms of maternal history of placental detachment, maternal diabetes, prolonged rupture of membranes, oligohydramnios, chorioamnionitis, multiple birth pregnancy, placental previa, intrauterine growth retardation, and late deceleration of fetal heart rate. Fetal acidosis was reported in 7.2% of cases with intrauterine growth restriction (N=30) (OR=3.1), 8.3% of neonates with placental detachment (N=15) (OR= 2.25), 7.2% of cases with chorioamnionitis (N=13) (OR=4.54) 14.9% of multiple births (N=27) (OR=1.79), 5.5% of cases with maternal anemia (N=10) (OR= 2.64), and 28.6% of newborns with late deceleration of fetal heart rate (N=44) (OR= 57%) (P= 0.001, 0.002, 0.03, 0.03, 0.04, and 0.03, respectively). However, fetal acidosis was not significantly associated with prolonged rupture of membranes, placental previa, oligohydramnios, preeclampsia, maternal diabetes, or diseases of the lung, liver, and kidney. Intrauterine growth retardation, chorioamnionitis, placental detachment, multiple birth pregnancy, maternal anemia, and late deceleration of fetal heart rate increased the risk of fetal acidosis in premature births.

Preterm delivery is a serious problem in pregnancy that its incidence is increasing. It is associated with multiple neonatal and long term complications. The aim of this study was to evaluate the correlation between neonatal outcome and umbilical artery pH in order to predict and prevent the neonatal complications that are most likely to occur if there is acidosis.

This case-control study was performed on 181 preterm neonates (27-37 gestational weeks) with acidosis of pH<7. 1 as a case group and 419 preterm neonates without acidosis as a control group who born at Ayatollah Roohani hospital of Babol during one year. Neonatal complications including admission in NICU، respiratory distress syndrome (RDS)، intraventricular hemorrhage (IVH)، retinopathy of prematurity (ROP)، disseminated intravascular coagulopathy (DIC)، necrotizing enterocolitis (NEC)، bronchopulmonary dysplasia (BPD)، sepsis، and neonatal death were compared and analyzed in both groups.

There was a significant relationship between neonatal acidosis and the complications including admission in NICU (OR=24)، RDS (OR=6. 4)، ROP (OR=8. 5)، also there was a significant relationship between acidosis and sepsis، hypoxic encephalopathy، IVH، DIC and neonatal death (p=0. 001) but no significant relationship was observed between BPD، NEC، and neonatal acidosis.

The results showed that in the case of neonatal necrosis، most neonatal complications following preterm birth are likely to increase.